A Peptidomimetic Antibiotic Targets Outer Membrane Proteins and Disrupts Selectively the Outer Membrane inEscherichia coli

Periplasmic quality control in biogenesis of outer membrane proteins

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Antimicrobial Peptides as an Opportunity Against Bacterial Diseases

(2015) Stefania Galdiero et al.   CURRENT MEDICINAL CHEMISTRY

Assembly of the secretion pores GspD, Wza and CsgG into bacterial outer membranes does not require the Omp85 proteins BamA or TamA

(2015) Rhys A. Dunstan et al.   MOLECULAR MICROBIOLOGY

Supramolecular assemblies underpin turnover of outer membrane proteins in bacteria

(2015) Patrice Rassam et al.   NATURE

The proline-rich antimicrobial peptide Onc112 inhibits translation by blocking and destabilizing the initiation complex

(2015) A Carolin Seefeldt et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin

(2015) Raktim N Roy et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The proline-rich antimicrobial peptide Onc112 inhibits translation by blocking and destabilizing the initiation complex

(2015) A Carolin Seefeldt et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin

(2015) Raktim N Roy et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Antibacterial Mechanisms of Polymyxin and Bacterial Resistance

(2015) Zhiliang Yu et al.   Biomed Research International

Biosynthesis and Export of Bacterial Lipopolysaccharides

(2014) Chris Whitfield et al.   Annual Review of Biochemistry

Probing the Penetration of Antimicrobial Polymyxin Lipopeptides into Gram-Negative Bacteria

(2014) Zakuan Z. Deris et al.   BIOCONJUGATE CHEMISTRY

Salmonellae PhoPQ regulation of the outer membrane to resist innate immunity

(2014) Zachary D Dalebroux et al.   CURRENT OPINION IN MICROBIOLOGY

Discovery and development of new antibacterial agents targeting Gram-negative bacteria in the era of pandrug resistance: is the future promising?

(2014) Malcolm GP Page et al.   CURRENT OPINION IN PHARMACOLOGY

Structural and functional analysis of the β-barrel domain of BamA from Escherichia coli

(2014) Dongchun Ni et al.   FASEB JOURNAL

MicL, a new  E-dependent sRNA, combats envelope stress by repressing synthesis of Lpp, the major outer membrane lipoprotein

(2014) M. S. Guo et al.   GENES & DEVELOPMENT

Proteome-wide identification of predominant subcellular protein localizations in a bacterial model organism

(2014) Daniel J. Stekhoven et al.   Journal of Proteomics

Structural basis for outer membrane lipopolysaccharide insertion

(2014) Haohao Dong et al.   NATURE

Structural basis for lipopolysaccharide insertion in the bacterial outer membrane

(2014) Shuai Qiao et al.   NATURE

Outer membrane  -barrel protein folding is physically controlled by periplasmic lipid head groups and BamA

(2014) D. Gessmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lateral Opening and Exit Pore Formation Are Required for BamA Function

(2014) Nicholas Noinaj et al.   STRUCTURE

Structure of BamA, an essential factor in outer membrane protein biogenesis

(2014) Reinhard Albrecht et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

On the essentiality of lipopolysaccharide to Gram-negative bacteria

(2013) Ge Zhang et al.   CURRENT OPINION IN MICROBIOLOGY

Directed shotgun proteomics guided by saturated RNA-seq identifies a complete expressed prokaryotic proteome

(2013) Ulrich Omasits et al.   GENOME RESEARCH

Structural insight into the biogenesis of β-barrel membrane proteins

(2013) Nicholas Noinaj et al.   NATURE

Response of Burkholderia cenocepacia H111 to Micro-Oxia

(2013) Gabriella Pessi et al.   PLoS One

Dual Molecular Signals Mediate the Bacterial Response to Outer-Membrane Stress

(2013) S. Lima et al.   SCIENCE

Inhibition of Lipopolysaccharide Transport to the Outer Membrane in Pseudomonas aeruginosa by Peptidomimetic Antibiotics

(2012) Martina Werneburg et al.   CHEMBIOCHEM

Analysis of Surface Protein Expression Reveals the Growth Pattern of the Gram-Negative Outer Membrane

(2012) Tristan S. Ursell et al.   PLoS Computational Biology

β-Barrel Membrane Protein Assembly by the Bam Complex

(2011) Christine L. Hagan et al.   Annual Review of Biochemistry

Designing antimicrobial peptides: form follows function

(2011) Christopher D. Fjell et al.   NATURE REVIEWS DRUG DISCOVERY

Real-time attack on single Escherichia coli cells by the human antimicrobial peptide LL-37

(2011) K. A. Sochacki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small RNAs endow a transcriptional activator with essential repressor functions for single-tier control of a global stress regulon

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Ligand-gated diffusion across the bacterial outer membrane

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Damage of the Bacterial Cell Envelope by Antimicrobial Peptides Gramicidin S and PGLa as Revealed by Transmission and Scanning Electron Microscopy

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PSORTb 3.0: improved protein subcellular localization prediction with refined localization subcategories and predictive capabilities for all prokaryotes

(2010) Nancy Y. Yu et al.   BIOINFORMATICS

PeptideClassifier for protein inference and targeted quantitative proteomics

(2010) Ermir Qeli et al.   NATURE BIOTECHNOLOGY

Nonconsecutive disulfide bond formation in an essential integral outer membrane protein

(2010) N. Ruiz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Peptidomimetic Antibiotics Target Outer-Membrane Biogenesis in Pseudomonas aeruginosa

(2010) N. Srinivas et al.   SCIENCE

Structure−Activity Relationships of Polymyxin Antibiotics

(2009) Tony Velkov et al.   JOURNAL OF MEDICINAL CHEMISTRY

Second messenger signalling governsEscherichia colibiofilm induction upon ribosomal stress

(2009) Alex Boehm et al.   MOLECULAR MICROBIOLOGY

β-Hairpin Peptidomimetics: Design, Structures and Biological Activities

(2008) John A. Robinson   ACCOUNTS OF CHEMICAL RESEARCH

Functional Analysis of the Protein Machinery Required for Transport of Lipopolysaccharide to the Outer Membrane of Escherichia coli

(2008) P. Sperandeo et al.   JOURNAL OF BACTERIOLOGY

The Extracytoplasmic Stress Factor, σE, Is Required to Maintain Cell Envelope Integrity in Escherichia coli

(2008) Jennifer D. Hayden et al.   PLoS One

Role of the cell envelope in the antibacterial activities of polymyxin B and polymyxin B nonapeptide against Escherichia coli

(2007) Ahmad Z. Sahalan et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS