Antibacterial Mechanisms of Polymyxin and Bacterial Resistance

Pharmacology of polymyxins: new insights into an ‘old’ class of antibiotics

(2013) Tony Velkov et al.   Future Microbiology

The molecular mechanisms and physiological consequences of oxidative stress: lessons from a model bacterium

(2013) James A. Imlay   NATURE REVIEWS MICROBIOLOGY

Rapid Killing of Acinetobacter baumannii by Polymyxins Is Mediated by a Hydroxyl Radical Death Pathway

(2012) Timothy R. Sampson et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Two-Component System CprRS Senses Cationic Peptides and Triggers Adaptive Resistance in Pseudomonas aeruginosa Independently of ParRS

(2012) Lucía Fernández et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Characterization of the Polymyxin B Resistome of Pseudomonas aeruginosa

(2012) Lucía Fernández et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Colistin: an update on the antibiotic of the 21st century

(2012) Silpak Biswas et al.   Expert Review of Anti-Infective Therapy

The PhoP/PhoQ System and Its Role in Serratia marcescens Pathogenesis

(2012) J. Barchiesi et al.   JOURNAL OF BACTERIOLOGY

Reciprocal Control between a Bacterium's Regulatory System and the Modification Status of Its Lipopolysaccharide

(2012) Akinori Kato et al.   MOLECULAR CELL

Intrinsic Negative Feedback Governs Activation Surge in Two-Component Regulatory Systems

(2012) Won-Sik Yeo et al.   MOLECULAR CELL

Insertion Sequence ISAba11Is Involved in Colistin Resistance and Loss of Lipopolysaccharide in Acinetobacter baumannii

(2011) Jennifer H. Moffatt et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

ThepmrCABOperon Mediates Polymyxin Resistance inAcinetobacter baumanniiATCC 17978 and Clinical Isolates through Phosphoethanolamine Modification of Lipid A

(2011) Luis A. Arroyo et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The PmrA/PmrB regulatory system controls the expression of the wzzfepE gene involved in the O-antigen synthesis of Salmonella enterica serovar Typhimurium

(2011) M. d. l. M. Pescaretti et al.   MICROBIOLOGY-SGM

Colistin Resistance in Acinetobacter baumannii Is Mediated by Complete Loss of Lipopolysaccharide Production

(2010) J. H. Moffatt et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Iron Homeostasis Affects Antibiotic-mediated Cell Death inPseudomonasSpecies

(2010) Jinki Yeom et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of PmrA inhibits LpxT-dependent phosphorylation of lipid A promoting resistance to antimicrobial peptides

(2010) Carmen M. Herrera et al.   MOLECULAR MICROBIOLOGY

A two-tier model of polymyxin B resistance in Burkholderia cenocepacia

(2010) Slade A. Loutet et al.   Environmental Microbiology Reports

Klebsiella pneumoniae AcrAB Efflux Pump Contributes to Antimicrobial Resistance and Virulence

(2009) E. Padilla et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Contribution of Each Amino Acid Residue in Polymyxin B3 to Antimicrobial and Lipopolysaccharide Binding Activity

(2009) Kazushi Kanazawa et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Identification of a Polymyxin Synthetase Gene Cluster of Paenibacillus polymyxa and Heterologous Expression of the Gene in Bacillus subtilis

(2009) S.-K. Choi et al.   JOURNAL OF BACTERIOLOGY

Interactions of Lipopolysaccharide and Polymyxin Studied by NMR Spectroscopy

(2009) Jiri Mares et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure−Activity Relationships of Polymyxin Antibiotics

(2009) Tony Velkov et al.   JOURNAL OF MEDICINAL CHEMISTRY

Different effects of transcriptional regulators MarA, SoxS and Rob on susceptibility of Escherichia coli to cationic antimicrobial peptides (CAMPs): Rob-dependent CAMP induction of the marRAB operon

(2009) D. M. Warner et al.   MICROBIOLOGY-SGM

Klebsiella pneumoniae OmpA Confers Resistance to Antimicrobial Peptides

(2008) E. Llobet et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Novel Polymyxin Derivatives Carrying Only Three Positive Charges Are Effective Antibacterial Agents

(2008) M. Vaara et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In vitro pharmacodynamics of colistin against multidrug-resistant Klebsiella pneumoniae

(2008) A. Poudyal et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Capsule polysaccharide is a bacterial decoy for antimicrobial peptides

(2008) E. Llobet et al.   MICROBIOLOGY-SGM

Tolerance to the antimicrobial peptide colistin in Pseudomonas aeruginosa biofilms is linked to metabolically active cells, and depends on the pmr and mexAB-oprM genes

(2008) Sünje Johanna Pamp et al.   MOLECULAR MICROBIOLOGY