The Wnt/Planar Cell Polarity Protein-tyrosine Kinase-7 (PTK7) Is a Highly Efficient Proteolytic Target of Membrane Type-1 Matrix Metalloproteinase

The tissue inhibitors of metalloproteinases (TIMPs): An ancient family with structural and functional diversity

(2010) Keith Brew et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear

(2010) Anju Paudyal et al.   BMC DEVELOPMENTAL BIOLOGY

Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

(2010) Kai Kessenbrock et al.   CELL

Golgi reassembly stacking protein 55 interacts with membrane-type (MT) 1-matrix metalloprotease (MMP) and furin and plays a role in the activation of the MT1-MMP zymogen

(2010) Christian Roghi et al.   FEBS Journal

Biochemical Characterization of the Cellular Glycosylphosphatidylinositol-linked Membrane Type-6 Matrix Metalloproteinase

(2010) Ilian A. Radichev et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Internal Cleavages of the Autoinhibitory Prodomain Are Required for Membrane Type 1 Matrix Metalloproteinase Activation, although Furin Cleavage Alone Generates Inactive Proteinase

(2010) Vladislav S. Golubkov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rho-ROCK-Myosin Signaling Meditates Membrane Type 1 Matrix Metalloproteinase-induced Cellular Aggregation of Keratinocytes

(2010) Surabhi Dangi-Garimella et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dendritic cell podosomes are protrusive and invade the extracellular matrix using metalloproteinase MMP-14

(2010) C. Gawden-Bone et al.   JOURNAL OF CELL SCIENCE

The planar cell polarity protein Van Gogh-Like 2 regulates tumor cell migration and matrix metalloproteinase-dependent invasion

(2009) V. Ashley Cantrell et al.   CANCER LETTERS

Inhibition of Rho-Associated Kinase Signaling Prevents Breast Cancer Metastasis to Human Bone

(2009) S. Liu et al.   CANCER RESEARCH

Dishevelled: The hub of Wnt signaling

(2009) Chan Gao et al.   CELLULAR SIGNALLING

PTK7 is essential for polarized cell motility and convergent extension during mouse gastrulation

(2009) W. W. Yen et al.   DEVELOPMENT

Wnt signaling pathways meet Rho GTPases

(2009) K. Schlessinger et al.   GENES & DEVELOPMENT

Wnt/Planar cell polarity signaling: A new paradigm for cancer therapy

(2009) Y. Wang   MOLECULAR CANCER THERAPEUTICS

Random versus directionally persistent cell migration

(2009) Ryan J. Petrie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Matrix Metalloproteinase Proteolysis of the Myelin Basic Protein Isoforms Is a Source of Immunogenic Peptides in Autoimmune Multiple Sclerosis

(2009) Sergey A. Shiryaev et al.   PLoS One

Regulation of convergence and extension movements during vertebrate gastrulation by the Wnt/PCP pathway

(2009) Isabelle Roszko et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Noncanonical Wnt/PCP Signaling During Vertebrate Gastrulation

(2009) Masazumi Tada et al.   Zebrafish

The Emerging Role of Wnt/PCP Signaling in Organ Formation

(2009) Rodney M. Dale et al.   Zebrafish

Noncanonical Wnt Signaling in Tumor Progression and Metastasis

(2009) Jason R. Jessen   Zebrafish

Planar Cell Polarity Signaling: The Developing Cell's Compass

(2009) E. K. Vladar et al.   Cold Spring Harbor Perspectives in Biology

Planar Cell Polarity Signaling: From Fly Development to Human Disease

(2008) Matias Simons et al.   Annual Review of Genetics

Soluble PTK7 inhibits tube formation, migration, and invasion of endothelial cells and angiogenesis

(2008) Won-Sik Shin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Molecular Signature of MT1-MMP: Transactivation of the Downstream Universal Gene Network in Cancer

(2008) D. V. Rozanov et al.   CANCER RESEARCH

Mapping proteolytic cancer cell-extracellular matrix interfaces

(2008) Katarina Wolf et al.   CLINICAL & EXPERIMENTAL METASTASIS

PTK7 recruits dsh to regulate neural crest migration

(2008) I. Shnitsar et al.   DEVELOPMENT

Membrane-type 1 matrix metalloproteinase regulates cell migration during zebrafish gastrulation: Evidence for an interaction with non-canonical Wnt signaling

(2008) Rebecca C. Coyle et al.   EXPERIMENTAL CELL RESEARCH

The Plane Facts of PCP in the CNS

(2008) Lisa V. Goodrich   NEURON

MODBASE, a database of annotated comparative protein structure models and associated resources

(2008) U. Pieper et al.   NUCLEIC ACIDS RESEARCH

Role of TGF-  in proliferative vitreoretinal diseases and ROCK as a therapeutic target

(2008) T. Kita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane type 1-matrix metalloproteinase: Substrate diversity in pericellular proteolysis☆

(2007) M BARBOLINA et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY