The Cytosolic Domain of Protein-tyrosine Kinase 7 (PTK7), Generated from Sequential Cleavage by a Disintegrin and Metalloprotease 17 (ADAM17) and γ-Secretase, Enhances Cell Proliferation and Migration in Colon Cancer Cells

The many roles of PTK7: A versatile regulator of cell–cell communication

(2012) Hanna Peradziryi et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Expression Profiling of Liposarcoma Yields a Multigene Predictor of Patient Outcome and Identifies Genes That Contribute to Liposarcomagenesis

(2011) R. M. Gobble et al.   CANCER RESEARCH

Global Gene Expression Profiling and Validation in Esophageal Squamous Cell Carcinoma and Its Association with Clinical Phenotypes

(2011) H. Su et al.   CLINICAL CANCER RESEARCH

RACK1 is a novel interaction partner of PTK7 that is required for neural tube closure

(2011) Peter Wehner et al.   DEVELOPMENT

PTK7/Otk interacts with Wnts and inhibits canonical Wnt signalling

(2011) Hanna Peradziryi et al.   EMBO JOURNAL

PlexinA1 interacts with PTK7 and is required for neural crest migration

(2010) Gabriele Wagner et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The cell polarity PTK7 receptor acts as a modulator of the chemotherapeutic response in acute myeloid leukemia and impairs clinical outcome

(2010) T. Prebet et al.   BLOOD

Protein tyrosine kinase 7 has a conserved role in Wnt/β-catenin canonical signalling

(2010) Francesca Puppo et al.   EMBO REPORTS

The Wnt/Planar Cell Polarity Protein-tyrosine Kinase-7 (PTK7) Is a Highly Efficient Proteolytic Target of Membrane Type-1 Matrix Metalloproteinase

(2010) Vladislav S. Golubkov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Silencing of PTK7 in Colon Cancer Cells: Caspase-10-Dependent Apoptosis via Mitochondrial Pathway

(2010) Ling Meng et al.   PLoS One

Identification of Ligand-Induced Proteolytic Cleavage and Ectodomain Shedding of VEGFR-1/FLT1 in Leukemic Cancer Cells

(2009) N. Rahimi et al.   CANCER RESEARCH

Matrix Metalloproteinases As Novel Biomarker s and Potential Therapeutic Targets in Human Cancer

(2009) Roopali Roy et al.   JOURNAL OF CLINICAL ONCOLOGY

Identification of Serum Biomarkers for Colorectal Cancer Metastasis Using a Differential Secretome Approach

(2009) Hua Xue et al.   JOURNAL OF PROTEOME RESEARCH

Soluble PTK7 inhibits tube formation, migration, and invasion of endothelial cells and angiogenesis

(2008) Won-Sik Shin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Substrate specificity of γ-secretase and other intramembrane proteases

(2008) A. J. Beel et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

PTK7 recruits dsh to regulate neural crest migration

(2008) I. Shnitsar et al.   DEVELOPMENT

The ADAM metalloproteinases

(2008) D EDWARDS et al.   MOLECULAR ASPECTS OF MEDICINE

The “A Disintegrin And Metalloprotease” (ADAM) family of sheddases: Physiological and cellular functions

(2008) Karina Reiss et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY