Identification and Small Molecule Inhibition of an Activating Transcription Factor 4 (ATF4)-dependent Pathway to Age-related Skeletal Muscle Weakness and Atrophy

AMPK Activation of Muscle Autophagy Prevents Fasting-Induced Hypoglycemia and Myopathy during Aging

(2015) Adam L. Bujak et al.   Cell Metabolism

Use of mRNA expression signatures to discover small molecule inhibitors of skeletal muscle atrophy

(2015) Christopher M. Adams et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

p53 and ATF4 mediate distinct and additive pathways to skeletal muscle atrophy during limb immobilization

(2014) Daniel K. Fox et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Systems-based Discovery of Tomatidine as a Natural Small Molecule Inhibitor of Skeletal Muscle Atrophy

(2014) Michael C. Dyle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thigh muscle volume in relation to age, sex and femur volume

(2013) T. M. Maden-Wilkinson et al.   AGE

Maintenance of muscle mass and load-induced growth in Muscle RING Finger 1 null mice with age

(2013) Darren T. Hwee et al.   AGING CELL

Skeletal muscle denervation causes skeletal muscle atrophy through a pathway that involves both Gadd45a and HDAC4

(2013) Kale S. Bongers et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Signalling pathways regulating muscle mass in ageing skeletal muscle. The role of the IGF1-Akt-mTOR-FoxO pathway

(2013) M. Sandri et al.   BIOGERONTOLOGY

Sustained Activation of mTORC1 in Skeletal Muscle Inhibits Constitutive and Starvation-Induced Autophagy and Causes a Severe, Late-Onset Myopathy

(2013) Perrine Castets et al.   Cell Metabolism

Mechanisms of skeletal muscle aging: insights from Drosophila and mammalian models

(2013) F. Demontis et al.   Disease Models & Mechanisms

Exercise and Nutrition to Target Protein Synthesis Impairments in Aging Skeletal Muscle

(2013) Jared M. Dickinson et al.   EXERCISE AND SPORT SCIENCES REVIEWS

Regulation of muscle protein synthesis and the effects of catabolic states

(2013) Bradley S. Gordon et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Anticarcinogenic, Cardioprotective, and Other Health Benefits of Tomato Compounds Lycopene, α-Tomatine, and Tomatidine in Pure Form and in Fresh and Processed Tomatoes

(2013) Mendel Friedman   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Rapamycin extends murine lifespan but has limited effects on aging

(2013) Frauke Neff et al.   JOURNAL OF CLINICAL INVESTIGATION

ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death

(2013) Jaeseok Han et al.   NATURE CELL BIOLOGY

Ursolic acid directly promotes protein accretion in myotubes but does not affect myoblast proliferation

(2012) Vandré Casagrande Figueiredo et al.   CELL BIOCHEMISTRY AND FUNCTION

Measuring Protein Synthesis With SUnSET

(2012) Craig A. Goodman et al.   EXERCISE AND SPORT SCIENCES REVIEWS

Stress-induced Skeletal Muscle Gadd45a Expression Reprograms Myonuclei and Causes Muscle Atrophy

(2012) Scott M. Ebert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genomic and Proteomic Profiling Reveals Reduced Mitochondrial Function and Disruption of the Neuromuscular Junction Driving Rat Sarcopenia

(2012) C. Ibebunjo et al.   MOLECULAR AND CELLULAR BIOLOGY

Ursolic Acid Increases Skeletal Muscle and Brown Fat and Decreases Diet-Induced Obesity, Glucose Intolerance and Fatty Liver Disease

(2012) Steven D. Kunkel et al.   PLoS One

Eukaryotic Initiation Factor 2 Phosphorylation and Translational Control in Metabolism

(2012) Thomas D. Baird et al.   Advances in Nutrition

mRNA Expression Signatures of Human Skeletal Muscle Atrophy Identify a Natural Compound that Increases Muscle Mass

(2011) Steven D. Kunkel et al.   Cell Metabolism

The Transcription Factor ATF4 Promotes Skeletal Myofiber Atrophy during Fasting

(2010) Scott M. Ebert et al.   MOLECULAR ENDOCRINOLOGY

Increased muscle PGC-1  expression protects from sarcopenia and metabolic disease during aging

(2009) T. Wenz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Isolation of ursolic acid from apple peels by high speed counter-current chromatography

(2007) Rosa T.S. Frighetto et al.   FOOD CHEMISTRY

Activating transcription factor 4

(2007) Kurosh Ameri et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY