Subcellular Distribution of NAD+between Cytosol and Mitochondria Determines the Metabolic Profile of Human Cells

NAD Biosynthesis in Humans - Enzymes, Metabolites and Therapeutic Aspects

(2015) Christian Dölle et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

NAD depletion by FK866 induces autophagy

(2014) Richard A. Billington et al.   Autophagy

Deficiency of Nicotinamide Mononucleotide Adenylyltransferase 3 (Nmnat3) Causes Hemolytic Anemia by Altering the Glycolytic Flow in Mature Erythrocytes

(2014) Keisuke Hikosaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The HumanSLC25A33andSLC25A36Genes of Solute Carrier Family 25 Encode Two Mitochondrial Pyrimidine Nucleotide Transporters

(2014) Maria Antonietta Di Noia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial transporters of the SLC25 family and associated diseases: a review

(2014) Ferdinando Palmieri   JOURNAL OF INHERITED METABOLIC DISEASE

Poly(ADP-ribose) polymerase-dependent energy depletion occurs through inhibition of glycolysis

(2014) S. A. Andrabi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ARTD1/PARP1 Negatively Regulates Glycolysis by Inhibiting Hexokinase 1 Independent of NAD + Depletion

(2014) Elise Fouquerel et al.   Cell Reports

NAD and ADP-ribose metabolism in mitochondria

(2013) Christian Dölle et al.   FEBS Journal

Insight into Molecular and Functional Properties of NMNAT3 Reveals New Hints of NAD Homeostasis within Human Mitochondria

(2013) Roberta Felici et al.   PLoS One

Axonal protection by Nmnat3 overexpression with involvement of autophagy in optic nerve degeneration

(2013) Y Kitaoka et al.   Cell Death & Disease

Pharmacological Inhibition of Nicotinamide Phosphoribosyltransferase (NAMPT), an Enzyme Essential for NAD+Biosynthesis, in Human Cancer Cells

(2012) Bo Tan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The mitochondrial transporter family SLC25: Identification, properties and physiopathology

(2012) Ferdinando Palmieri   MOLECULAR ASPECTS OF MEDICINE

The dynamic regulation of NAD metabolism in mitochondria

(2012) Liana Roberts Stein et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Deletion or Overexpression of Mitochondrial NAD+Carriers inSaccharomyces cerevisiaeAlters Cellular NAD and ATP Contents and Affects Mitochondrial Metabolism and the Rate of Glycolysis

(2011) Gennaro Agrimi et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The human geneSLC25A17encodes a peroxisomal transporter of coenzyme A, FAD and NAD+

(2011) Gennaro Agrimi et al.   BIOCHEMICAL JOURNAL

Mitochondria as a Therapeutic Target for Aging and Neurodegenerative Diseases

(2011) P. H. Reddy et al.   Current Alzheimer Research

Pathways and Subcellular Compartmentation of NAD Biosynthesis in Human Cells

(2011) Andrey Nikiforov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial dysfunction and nicotinamide dinucleotide catabolism as mechanisms of cell death and promising targets for neuroprotection

(2011) Tibor Kristian et al.   JOURNAL OF NEUROSCIENCE RESEARCH

The role of mitochondria in insulin resistance and type 2 diabetes mellitus

(2011) Julia Szendroedi et al.   Nature Reviews Endocrinology

Mitochondria-localized NAD biosynthesis by nicotinamide mononucleotide adenylyltransferase in Jerusalem artichoke (Helianthus tuberosus L.) heterotrophic tissues

(2011) Catello Di Martino et al.   PLANTA

Unique expression pattern of human nicotinamide mononucleotide adenylyltransferase isozymes in red blood cells

(2010) M. Di Stefano et al.   BLOOD CELLS MOLECULES AND DISEASES

The Secret Life of NAD+: An Old Metabolite Controlling New Metabolic Signaling Pathways

(2010) Riekelt H. Houtkooper et al.   ENDOCRINE REVIEWS

Inhibition of Nicotinamide Phosphoribosyltransferase

(2010) Maria Pittelli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NAD+ Depletion Is Necessary and Sufficient forPoly(ADP-Ribose) Polymerase-1-Mediated Neuronal Death

(2010) C. C. Alano et al.   JOURNAL OF NEUROSCIENCE

A Preclinical Study on the Rescue of Normal Tissue by Nicotinic Acid in High-Dose Treatment with APO866, a Specific Nicotinamide Phosphoribosyltransferase Inhibitor

(2010) U. H. Olesen et al.   MOLECULAR CANCER THERAPEUTICS

Jalview Version 2--a multiple sequence alignment editor and analysis workbench

(2009) A. M. Waterhouse et al.   BIOINFORMATICS

Visualization of subcellular NAD pools and intra-organellar protein localization by poly-ADP-ribose formation

(2009) Christian Dölle et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Molecular Identification and Functional Characterization ofArabidopsis thalianaMitochondrial and Chloroplastic NAD+Carrier Proteins

(2009) Ferdinando Palmieri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Catastrophic NAD+ Depletion in Activated T Lymphocytes through Nampt Inhibition Reduces Demyelination and Disability in EAE

(2009) Santina Bruzzone et al.   PLoS One

Emerging Roles of NAD+ and Its Metabolites in Cell Signaling

(2009) F. Koch-Nolte et al.   Science Signaling

Diseases caused by defects of mitochondrial carriers: A review

(2008) Ferdinando Palmieri   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS