Axonal protection by Nmnat3 overexpression with involvement of autophagy in optic nerve degeneration

Lysosomal basification and decreased autophagic flux in oxidatively stressed trabecular meshwork cells

(2013) Kristine Porter et al.   Autophagy

The Pro-Survival Role of Autophagy Depends on Bcl-2 Under Nutrition Stress Conditions

(2013) Hai-Dong Xu et al.   PLoS One

Autophagy protein p62/SQSTM1 is involved in HAMLET-induced cell death by modulating apotosis in U87MG cells

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Molecular chaperones protect against JNK- and Nmnat-regulated axon degeneration in Drosophila

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The role of autophagy in Nmnat-mediated protection against hypoxia-induced dendrite degeneration

(2012) Yuhui Wen et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Activation of autophagy induces retinal ganglion cell death in a chronic hypertensive glaucoma model

(2012) H-Y Lopilly Park et al.   Cell Death & Disease

The Highwire Ubiquitin Ligase Promotes Axonal Degeneration by Tuning Levels of Nmnat Protein

(2012) Xin Xiong et al.   PLOS BIOLOGY

Accumulation of p62 in degenerated spinal cord under chronic mechanical compression

(2011) Fumito Tanabe et al.   Autophagy

Selective autophagy mediated by autophagic adapter proteins

(2011) Terje Johansen et al.   Autophagy

Triage of oxidation-prone proteins by Sqstm1/p62 within the mitochondria

(2011) Minjung Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Autophagy promotes survival of retinal ganglion cells after optic nerve axotomy in mice

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Axonal Protection by 17β-Estradiol through Thioredoxin-1 in Tumor Necrosis Factor-Induced Optic Neuropathy

(2011) Yasushi Kitaoka et al.   ENDOCRINOLOGY

p62 targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding

(2011) Eisuke Itakura et al.   JOURNAL OF CELL BIOLOGY

Calpain-mediated cleavage of Beclin-1 and autophagy deregulation following retinal ischemic injury in vivo

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Autophagy Is a Renoprotective Mechanism During in Vitro Hypoxia and in Vivo Ischemia-Reperfusion Injury

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(2010) Noboru Mizushima et al.   CELL

Pathophysiology of human glaucomatous optic nerve damage: Insights from rodent models of glaucoma

(2010) John C. Morrison et al.   EXPERIMENTAL EYE RESEARCH

Modulation of mitochondria in the axon and soma of retinal ganglion cells in a rat glaucoma model

(2010) Yasunari Munemasa et al.   JOURNAL OF NEUROCHEMISTRY

Selective degradation of p62 by autophagy

(2010) Yoshinobu Ichimura et al.   Seminars in Immunopathology

Endogenous Nmnat2 Is an Essential Survival Factor for Maintenance of Healthy Axons

(2010) Jonathan Gilley et al.   PLOS BIOLOGY

Axonal and Cell Body Protection By Nicotinamide Adenine Dinucleotide in Tumor Necrosis Factor-Induced Optic Neuropathy

(2009) Yasushi Kitaoka et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Nicotinamide Mononucleotide Adenylyltransferase Expression in Mitochondrial Matrix Delays Wallerian Degeneration

(2009) N. Yahata et al.   JOURNAL OF NEUROSCIENCE

Transgenic Mice Expressing the Nmnat1 Protein Manifest Robust Delay in Axonal Degeneration In Vivo

(2009) Y. Sasaki et al.   JOURNAL OF NEUROSCIENCE

Nmnat2 delays axon degeneration in superior cervical ganglia dependent on its NAD synthesis activity

(2009) Tingting Yan et al.   NEUROCHEMISTRY INTERNATIONAL

Redox proteins thioredoxin 1 and thioredoxin 2 support retinal ganglion cell survival in experimental glaucoma

(2008) Y Munemasa et al.   GENE THERAPY

Nmnat Delays Axonal Degeneration Caused by Mitochondrial and Oxidative Stress

(2008) C. Press et al.   JOURNAL OF NEUROSCIENCE

Activation of autophagy in retinal ganglion cells

(2008) Seok Hwan Kim et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE