Nuclear Factor of Activated T Cells-dependent Down-regulation of the Transcription Factor Glioma-associated Protein 1 (GLI1) Underlies the Growth Inhibitory Properties of Arachidonic Acid

The Transcription Factor GLI1 Interacts with SMAD Proteins to Modulate Transforming Growth Factor β-Induced Gene Expression in a p300/CREB-binding Protein-associated Factor (PCAF)-dependent Manner

(2014) Monica D. Nye et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polyunsaturated fatty acids and gliomas: A critical review of experimental, clinical, and epidemiologic data

(2014) Silvana Silvia Sandrone et al.   NUTRITION

ω-3 Polyunsaturated fatty acids-derived lipid metabolites on angiogenesis, inflammation and cancer

(2014) Weicang Wang et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Inflammation-Induced NFATc1-STAT3 Transcription Complex Promotes Pancreatic Cancer Initiation by KrasG12D

(2014) S. Baumgart et al.   Cancer Discovery

NFAT Gene Family in Inflammation and Cancer

(2013) M.-G. Pan et al.   CURRENT MOLECULAR MEDICINE

Loss of the Transcription Factor GLI1 Identifies a Signaling Network in the Tumor Microenvironment Mediating KRAS Oncogene-induced Transformation

(2013) Lisa D. Mills et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In Vitro and In Vivo Safety Evaluation of Biodegradable Self-Assembled Monomethyl Poly (Ethylene Glycol)–Poly(ε-Caprolactone)–Poly (Trimethylene Carbonate) Micelles

(2013) Xi Yang et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Effects of polyunsaturated fatty acids on the growth of gastric cancer cells in vitro

(2013) Jinfeng Dai et al.   Lipids in Health and Disease

Crosstalk among dietary polyunsaturated fatty acids, urolithiasis, chronic inflammation, and urinary tract tumor risk

(2013) Aldo R. Eynard et al.   NUTRITION

Immunomodulation by dietary long chain omega-3 fatty acids and the potential for adverse health outcomes

(2013) Jenifer I. Fenton et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Current Evidence Linking Polyunsaturated Fatty Acids with Cancer Risk and Progression

(2013) Maria Azrad et al.   Frontiers in Oncology

Fatty acid patterns and risk of prostate cancer in a case-control study nested within the European Prospective Investigation into Cancer and Nutrition

(2012) Christina C Dahm et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

New insights into the health effects of dietary saturated and omega-6 and omega-3 polyunsaturated fatty acids

(2012) Michel de Lorgeril et al.   BMC Medicine

Interaction Between NFκB and NFAT Coordinates Cardiac Hypertrophy and Pathological Remodeling

(2012) Qinghang Liu et al.   CIRCULATION RESEARCH

Novel Interactions between NFATc1 (Nuclear Factor of Activated T Cells c1) and STAT-3 (Signal Transducer and Activator of Transcription-3) Mediate G Protein-coupled Receptor Agonist, Thrombin-induced Biphasic Expression of Cyclin D1, with First Phase Influencing Cell Migration and Second Phase Directing Cell Proliferation

(2012) Venkatesh Kundumani-Sridharan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel AKT1-GLI3-VMP1 Pathway Mediates KRAS Oncogene-induced Autophagy in Cancer Cells

(2012) Andrea E. Lo Ré et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

EPA, an omega-3 fatty acid, induces apoptosis in human pancreatic cancer cells: Role of ROS accumulation, caspase-8 activation, and autophagy induction

(2012) Masayuki Fukui et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Role of mitochondria in programmed cell death mediated by arachidonic acid-derived eicosanoids

(2012) Huiyong Yin et al.   MITOCHONDRION

Selective Induction of Cell Death in Melanoma Cell Lines through Targeting of Mcl-1 and A1

(2012) Daniela Senft et al.   PLoS One

Immunotherapy with HER-2 and VEGF peptide mimics plus metronomic paclitaxel causes superior antineoplastic effects in transplantable and transgenic mouse models of human breast cancer

(2012) Kevin C. Foy et al.   OncoImmunology

Basic aspects of tumor cell fatty acid-regulated signaling and transcription factors

(2011) Andrea Comba et al.   CANCER AND METASTASIS REVIEWS

Restricted Heterochromatin Formation Links NFATc2 Repressor Activity With Growth Promotion in Pancreatic Cancer

(2011) Sandra Baumgart et al.   GASTROENTEROLOGY

GLI2 Transcription Factor Mediates Cytokine Cross-talk in the Tumor Microenvironment

(2011) Sherine F. Elsawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Non-esterified polyunsaturated fatty acids distinctly modulate the mitochondrial and cellular ROS production in normoxia and hypoxia

(2011) Peter Schönfeld et al.   JOURNAL OF NEUROCHEMISTRY

Effect of polyunsaturated fatty acids on drug-sensitive and resistant tumor cells in vitro

(2011) Undurti N Das et al.   Lipids in Health and Disease

MicroRNA profile of polyunsaturated fatty acid treated glioma cells reveal apoptosis-specific expression changes

(2011) Nóra Faragó et al.   Lipids in Health and Disease

Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes

(2011) D. Biswas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The calcineurin/NFAT signaling pathway: A NOVEL therapeutic target in leukemia and solid tumors

(2010) Hind Medyouf et al.   CELL CYCLE

Omega-3 fatty acids in cancer, the protectors of good and the killers of evil?

(2010) Helena Gleissman et al.   EXPERIMENTAL CELL RESEARCH

The CCAAT/Enhancer Binding Protein β (C/EBPβ) Cooperates with NFAT to Control Expression of the Calcineurin Regulatory ProteinRCAN1–4

(2010) Misook Oh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of calcium and ROS in cell death induced by polyunsaturated fatty acids in murine thymocytes

(2010) Aparna Prasad et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Enhancing Cytotoxic Therapies for Breast and Prostate Cancers With Polyunsaturated Fatty Acids

(2010) Irshad A. A. Shaikh et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Primers on Molecular Pathways —The NFAT Transcription Pathway in Pancreatic Cancer

(2010) Alexander König et al.   PANCREATOLOGY

NFAT-Induced Histone Acetylation Relay Switch Promotes c-Myc-Dependent Growth in Pancreatic Cancer Cells

(2009) Alexander Köenig et al.   GASTROENTEROLOGY

GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation

(2009) O. Nolan-Stevaux et al.   GENES & DEVELOPMENT

Gamma-linolenic acid inhibits both tumour cell cycle progression and angiogenesis in the orthotopic C6 glioma model through changes in VEGF, Flt1, ERK1/2, MMP2, cyclin D1, pRb, p53 and p27 protein expression

(2009) Juliano Miyake et al.   Lipids in Health and Disease

Primers on Molecular Pathways — Lipoxygenases: Their Role as an Oncogenic Pathway in Pancreatic Cancer

(2009) A. Comba et al.   PANCREATOLOGY

Arachidonic acid induces Fas and FasL upregulation in human leukemia U937 cells via Ca2+/ROS-mediated suppression of ERK/c-Fos pathway and activation of p38 MAPK/ATF-2 pathway

(2009) Wen-Hsin Liu et al.   TOXICOLOGY LETTERS

Decreased Polyunsaturated Fatty Acid Content Contributes to Increased Survival in Human Colon Cancer

(2009) Manuela Oraldi et al.   Journal of Oncology

Polyunsaturated fatty acids block platelet-activating factor-induced phosphatidylinositol 3 kinase/Akt-mediated apoptosis in intestinal epithelial cells

(2008) Jing Lu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Involvement of PPARα in the growth inhibitory effect of arachidonic acid on breast cancer cells

(2008) Claudia Bocca et al.   BRITISH JOURNAL OF NUTRITION

Primers on Molecular Pathways GLI: More than Just Hedgehog?

(2008) Martín E. Fernández-Zapico   PANCREATOLOGY

Cholecystokinin Activates Pancreatic Calcineurin-NFAT Signaling In Vitro and In Vivo

(2007) Grzegorz T. Gurda et al.   MOLECULAR BIOLOGY OF THE CELL