Type I Interferon Signaling Is Decoupled from Specific Receptor Orientation through Lenient Requirements of the Transmembrane Domain
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Type I Interferon Signaling Is Decoupled from Specific Receptor Orientation through Lenient Requirements of the Transmembrane Domain
Authors
Keywords
-
Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 291, Issue 7, Pages 3371-3384
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2015-12-18
DOI
10.1074/jbc.m115.686071
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Interactions of the EGFR juxtamembrane domain with PIP 2 -containing lipid bilayers: Insights from multiscale molecular dynamics simulations
- (2015) Khairul Bariyyah Abd Halim et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands
- (2015) Ignacio Moraga et al. CELL
- Receptor dimerization dynamics as a regulatory valve for plasticity of type I interferon signaling
- (2015) Stephan Wilmes et al. JOURNAL OF CELL BIOLOGY
- The TOPCONS web server for consensus prediction of membrane protein topology and signal peptides
- (2015) Konstantinos D. Tsirigos et al. NUCLEIC ACIDS RESEARCH
- The molecular basis for functional plasticity in type I interferon signaling
- (2015) Gideon Schreiber et al. TRENDS IN IMMUNOLOGY
- Ligand regulation of a constitutively dimeric EGF receptor
- (2015) Daniel M. Freed et al. Nature Communications
- Putting together structures of epidermal growth factor receptors
- (2014) Nicholas J Bessman et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Live cell micropatterning reveals the dynamics of signaling complexes at the plasma membrane
- (2014) Sara Löchte et al. JOURNAL OF CELL BIOLOGY
- Dual Regulatory Roles of Phosphatidylinositol 3-Kinase in IFN Signaling
- (2014) S. Kaur et al. JOURNAL OF IMMUNOLOGY
- Structural basis of recognition of interferon-α receptor by tyrosine kinase 2
- (2014) Heidi J A Wallweber et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Multifaceted Activities of Type I Interferon Are Revealed by a Receptor Antagonist
- (2014) D. Levin et al. Science Signaling
- Structural and Functional Characterization of Alternative Transmembrane Domain Conformations in VEGF Receptor 2 Activation
- (2014) Sandro Manni et al. STRUCTURE
- How IGF-1 activates its receptor
- (2014) Jennifer M Kavran et al. eLife
- PREDDIMER: a web server for prediction of transmembrane helical dimers
- (2013) Anton A. Polyansky et al. BIOINFORMATICS
- Ligand-independent interaction of the type I interferon receptor complex is necessary to observe its biological activity
- (2013) Christopher D. Krause et al. CYTOKINE
- Endocytosis of EGFR requires its kinase activity and N-terminal transmembrane dimerization motif
- (2013) R. Heukers et al. JOURNAL OF CELL SCIENCE
- Structural basis of a unique interferon-β signaling axis mediated via the receptor IFNAR1
- (2013) Nicole A de Weerd et al. NATURE IMMUNOLOGY
- Tryptophan at the transmembrane-cytosolic junction modulates thrombopoietin receptor dimerization and activation
- (2013) J.-P. Defour et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Understanding cytokine and growth factor receptor activation mechanisms
- (2012) Mariya Atanasova et al. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- The JAK-STAT Pathway at Twenty
- (2012) George R. Stark et al. IMMUNITY
- The interferons and their receptors-distribution and regulation
- (2012) Nicole A de Weerd et al. IMMUNOLOGY AND CELL BIOLOGY
- A Common Model for Cytokine Receptor Activation: Combined Scissor-Like Rotation and Self-Rotation of Receptor Dimer Induced by Class I Cytokine
- (2012) Xiaodong Pang et al. PLoS Computational Biology
- Transmembrane helix dimerization: Beyond the search for sequence motifs
- (2011) Edwin Li et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Structural Linkage between Ligand Discrimination and Receptor Activation by Type I Interferons
- (2011) Christoph Thomas et al. CELL
- Orientation-specific signalling by thrombopoietin receptor dimers
- (2011) Judith Staerk et al. EMBO JOURNAL
- Stochastic Receptor Expression Determines Cell Fate upon Interferon Treatment
- (2011) D. Levin et al. MOLECULAR AND CELLULAR BIOLOGY
- USP18-Based Negative Feedback Control Is Induced by Type I and Type III Interferons and Specifically Inactivates Interferon α Response
- (2011) Véronique François-Newton et al. PLoS One
- Interferon alpha regulates MAPK and STAT1 pathways in human hepatoma cells
- (2011) Lan-Juan Zhao et al. Virology Journal
- ConSurf 2010: calculating evolutionary conservation in sequence and structure of proteins and nucleic acids
- (2010) H. Ashkenazy et al. NUCLEIC ACIDS RESEARCH
- Transmembrane domain-mediated orientation of receptor monomers in active VEGFR-2 dimers
- (2009) Debora Dell'Era Dosch et al. FASEB JOURNAL
- Structure and function of VEGF receptors
- (2009) Edward Stuttfeld et al. IUBMB LIFE
- INTREPID: a web server for prediction of functionally important residues by evolutionary analysis
- (2009) S. Sankararaman et al. NUCLEIC ACIDS RESEARCH
- Probing Protein Conformations by in Situ Non-Covalent Fluorescence Labeling
- (2008) Jennifer Julia Strunk et al. BIOCONJUGATE CHEMISTRY
- Interleukin-5 Receptor Subunit Oligomerization and Rearrangement Revealed by Fluorescence Resonance Energy Transfer Imaging
- (2008) Meirav Zaks-Zilberman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Stability of the Ternary Interferon-Receptor Complex Rather than the Affinity to the Individual Subunits Dictates Differential Biological Activities
- (2008) Eyal Kalie et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ligand Binding Induces a Conformational Change in ifnar1 that Is Propagated to Its Membrane-Proximal Domain
- (2008) Jennifer Julia Strunk et al. JOURNAL OF MOLECULAR BIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More