Artesunate Activates Mitochondrial Apoptosis in Breast Cancer Cells via Iron-catalyzed Lysosomal Reactive Oxygen Species Production

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

(2014) Daniel J. Klionsky et al.   Autophagy

First evidence that the antimalarial drug artesunate inhibits invasion and in vivo metastasis in lung cancer by targeting essential extracellular proteases

(2010) Suhail Ahmed Kabeer Rasheed et al.   INTERNATIONAL JOURNAL OF CANCER

HGF-induced invasion by prostate tumor cells requires anterograde lysosome trafficking and activity of Na+-H+ exchangers

(2010) J. J. Steffan et al.   JOURNAL OF CELL SCIENCE

Dihydroartemisinin inhibits growth of pancreatic cancer cells in vitro and in vivo

(2009) Hua Chen et al.   ANTI-CANCER DRUGS

Gene expression profiling identifies novel key players involved in the cytotoxic effect of Artesunate on pancreatic cancer cells

(2009) Mahmoud Youns et al.   BIOCHEMICAL PHARMACOLOGY

The Role of Downstream Signaling Pathways of the Epidermal Growth Factor Receptor for Artesunates Activity in Cancer Cells

(2009) V. Konkimalla et al.   CURRENT CANCER DRUG TARGETS

Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes

(2009) Anne Simonsen et al.   JOURNAL OF CELL BIOLOGY

Lysosomal involvement in cell death and cancer

(2008) Thomas Kirkegaard et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Artesunate Derived from Traditional Chinese Medicine Induces DNA Damage and Repair

(2008) P. C.H. Li et al.   CANCER RESEARCH

Experimental Therapy of Hepatoma with Artemisinin and Its Derivatives: In vitro and In vivo Activity, Chemosensitization, and Mechanisms of Action

(2008) J. Hou et al.   CLINICAL CANCER RESEARCH

Pharmacokinetics and tolerability of artesunate and amodiaquine alone and in combination in healthy volunteers

(2008) Catherine Orrell et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Mitochondrial dynamics and apoptosis

(2008) D.-F. Suen et al.   GENES & DEVELOPMENT

Translocation of iron from lysosomes into mitochondria is a key event during oxidative stress-induced hepatocellular injury

(2008) Akira Uchiyama et al.   HEPATOLOGY

Lysosomes in iron metabolism, ageing and apoptosis

(2008) Tino Kurz et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Cysteine Cathepsins Trigger Caspase-dependent Cell Death through Cleavage of Bid and Antiapoptotic Bcl-2 Homologues

(2008) Gabriela Droga-Mazovec et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rab5 modulates aggregation and toxicity of mutant huntingtin through macroautophagy in cell and fly models of Huntington disease

(2008) B. Ravikumar et al.   JOURNAL OF CELL SCIENCE

Caspase-8 is activated by cathepsin D initiating neutrophil apoptosis during the resolution of inflammation

(2008) Sébastien Conus et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Lysosomal membrane permeabilization in cell death

(2008) P Boya et al.   ONCOGENE

The Itinerary of Autophagosomes: From Peripheral Formation to Kiss-and-Run Fusion with Lysosomes

(2008) Luca Jahreiss et al.   TRAFFIC

Dual contrasting roles of cysteine cathepsins in cancer progression: Apoptosis versus tumour invasion

(2007) Olga Vasiljeva et al.   BIOCHIMIE

Targeting lysosomal degradation induces p53-dependent cell death and prevents cancer in mouse models of lymphomagenesis

(2007) Kirsteen H. Maclean et al.   JOURNAL OF CLINICAL INVESTIGATION