Autophagy-mediated HMGB1 release antagonizes apoptosis of gastric cancer cells induced by vincristine via transcriptional regulation of Mcl-1

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Tumor suppression by autophagy through the management of metabolic stress

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HMGB1 as an autophagy sensor in oxidative stress

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FTY720 produces caspase-independent cell death of acute lymphoblastic leukemia cells

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Following Cytochrome c Release, Autophagy Is Inhibited during Chemotherapy-Induced Apoptosis by Caspase 8-Mediated Cleavage of Beclin 1

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Hypoxia-increased RAGE and P2X7R expression regulates tumor cell invasion through phosphorylation of Erk1/2 and Akt and nuclear translocation of NF-κB

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At the core of survival: Autophagy delays the onset of both apoptotic and necrotic cell death in a model of ischemic cell injury

(2011) B. Loos et al.   EXPERIMENTAL CELL RESEARCH

Functions of Autophagy in Hepatic and Pancreatic Physiology and Disease

(2011) Mark J. Czaja   GASTROENTEROLOGY

SCFFBW7 regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction

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Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7

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Autophagy as a target for anticancer therapy

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The autophagy conundrum in cancer: influence of tumorigenic metabolic reprogramming

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Ets-1 mediates upregulation of Mcl-1 downstream of XBP-1 in human melanoma cells upon ER stress

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Cystatin B inhibition of TRAIL-induced apoptosis is associated with the protection of FLIPL from degradation by the E3 ligase itch in human melanoma cells

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TRAIL receptor signaling and therapeutics

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Endogenous HMGB1 regulates autophagy

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HMGB1-induced autophagy promotes chemotherapy resistance in leukemia cells

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Autophagy gone awry in neurodegenerative diseases

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HMGB1 release and redox regulates autophagy and apoptosis in cancer cells

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Regulation of Mammalian Autophagy in Physiology and Pathophysiology

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Cytotoxicity of apigenin on leukemia cell lines: implications for prevention and therapy

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Regulation of HMGB1 release by autophagy

(2009) Jacqueline Thorburn et al.   Autophagy

Potentiating effects of RAD001 (Everolimus) on vincristine therapy in childhood acute lymphoblastic leukemia

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Release of HMGB1 in Response to Proapoptotic Glioma Killing Strategies: Efficacy and Neurotoxicity

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Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival

(2009) Martin Schwickart et al.   NATURE

Macroautophagy and its role in nutrient homeostasis

(2009) Martha H Stipanuk   NUTRITION REVIEWS

ROLE OF TOLL-LIKE RECEPTORS 2 AND 4, AND THE RECEPTOR FOR ADVANCED GLYCATION END PRODUCTS IN HIGH-MOBILITY GROUP BOX 1-INDUCED INFLAMMATION IN VIVO

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Inhibition of MEK blocks GRP78 up-regulation and enhances apoptosis induced by ER stress in gastric cancer cells

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Unique Biology of Mcl-1: Therapeutic Opportunities in Cancer

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