Review
Cardiac & Cardiovascular Systems
Sang-Ho Jo, Seung Hwan Han, Sang-Hyun Kim, Robert H. Eckel, Kwang Kon Koh
Summary: The role of omega-3 fatty acids in patients on statin therapy is currently controversial, with conflicting results from different clinical trials. Factors such as the type, dosage, comparator, and severity of CVD risk may contribute to these varied outcomes.
Review
Biochemistry & Molecular Biology
Kamila P. Liput, Adam Lepczynski, Magdalena Ogluszka, Agata Nawrocka, Ewa Polawska, Agata Grzesiak, Brygida Slaska, Chandra S. Pareek, Urszula Czarnik, Mariusz Pierzchala
Summary: It is recommended to reduce saturated fatty acids (SFA) and increase polyunsaturated fatty acids (PUFAs) n-3 and n-6 in the diet to lower the risk of metabolic disorders. Western-type diet often contains excessive n-6 PUFAs and a high n-6/n-3 ratio. Oxylipins derived from n-3 and n-6 PUFAs play a role in inflammation, while PUFAs have varying effects on cell growth, proliferation, and neoplastic lesion progression, as observed in in vitro studies, animal models, and epidemiological studies.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Cardiac & Cardiovascular Systems
Anthony D. Pisaniello, Peter J. Psaltis, Peta M. King, Ge Liu, Robert A. Gibson, Joanne Tm Tan, MyNgan Duong, Tracy Nguyen, Christina A. Bursill, Matthew Worthley, Stephen J. Nicholls, Belinda A. Di Bartolo
Summary: The study demonstrates that EPA supplementation is more effective than DHA in reducing acute and chronic vascular inflammation, providing a rationale for the cardiovascular benefit observed with high-dose omega-3 fatty acid administration.
Review
Nutrition & Dietetics
Ivana Djuricic, Philip C. Calder
Summary: Oxidative stress and inflammation are important contributors to chronic non-communicable diseases. Different types of fatty acids have varying effects on chronic diseases, with moderate intake of Ω-6 fatty acids lowering the risk of cardiovascular diseases and Ω-3 fatty acids helping to reduce inflammation levels.
Article
Obstetrics & Gynecology
J. Stanhiser, A. M. Z. Jukic, D. R. McConnaughey, A. Z. Steiner
Summary: The study found that self-reported use of omega-3 fatty acid supplements was associated with an increased probability of conceiving.
HUMAN REPRODUCTION
(2022)
Review
Biochemistry & Molecular Biology
Roberta Cardim Lessa, Fabio de Abreu Alves, Erika Fortunati, Jun Lu
Summary: Oral mucositis (OM) is a painful condition caused by cancer treatments, impacting patients' quality of life and recovery. Current management strategies are insufficient, necessitating a search for new approaches. Utilizing ω-3 fatty acids to manage OM may be an effective strategy based on preliminary evidence.
Review
Nutrition & Dietetics
Daniel Rodriguez, Carl J. Lavie, Andrew Elagizi, Richard V. Milani
Summary: This paper discusses the importance of using omega-3 fatty acids in cardiovascular diseases and summarizes related research and recommendations.
Review
Psychiatry
Katherine H. O. Deane, Oluseyi F. Jimoh, Priti Biswas, Alex O'Brien, Sarah Hanson, Asmaa S. Abdelhamid, Chris Fox, Lee Hooper
Summary: The study found that increasing long-chain Omega-3 has little or no effect on preventing depression and anxiety symptoms, while increasing alpha-linolenic acid may slightly increase the risk of depression symptoms, but with low-quality evidence.
BRITISH JOURNAL OF PSYCHIATRY
(2021)
Article
Nutrition & Dietetics
Grace Austin, Jessica J. A. Ferguson, Rohith N. Thota, Harjinder Singh, Tracy Burrows, Manohar L. Garg
Summary: The study showed that LCn-3PUFA with or without MCSFA, but not MCSFA alone, are effective in reducing postprandial triglycerides in healthy individuals.
CLINICAL NUTRITION
(2021)
Article
Biochemistry & Molecular Biology
Kaitlyn B. Hartnett, Bradley J. Ferguson, Patrick M. Hecht, Luke E. Schuster, Joel I. Shenker, David R. Mehr, Kevin L. Fritsche, Martha A. Belury, Douglas W. Scharre, Adam J. Horwitz, Briana M. Kille, Briann E. Sutton, Paul E. Tatum, C. Michael Greenlief, David Q. Beversdorf
Summary: This pilot study aimed to explore the relationship between stress exposure and dietary omega-3 fatty acid intake in relation to the risk of Alzheimer's disease (AD). The results showed that among individuals with high stress exposure, healthy controls had significantly higher omega-3 fatty acid intake compared to AD patients. No difference was observed among those with low stress exposure. These preliminary findings suggest that omega-3 fatty acids may mitigate AD risk in the setting of greater stress exposure.
Article
Geriatrics & Gerontology
Roxana Coras, Brian Pedersen, Rekha Narasimhan, Anahy Brandy, Lourdes Mateo, Agueda Prior-Espanol, Arthur Kavanaugh, Aaron M. Armando, Mohit Jain, Oswald Quehenberger, Melania Martinez-Morillo, Monica Guma
Summary: The study revealed that arthritis symptoms in older adults were related to disturbances in serum oxylipins, suggesting that certain oxylipins may be key effectors in arthritis in this population.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2021)
Review
Nutrition & Dietetics
Luisa Martins Miller, Flavia Benetti Piccinin, Ubele van der Velden, Sabrina Carvalho Gomes
Summary: This systematic review examined the additional effect of taking omega-3 supplements on non-surgical periodontal therapy. The results showed a high level of uncertainty and no definitive conclusion about the benefits of omega-3 supplementation. However, two six-month studies showed promising effects, which encourage further research with better-defined protocols and greater methodological rigor.
Article
Immunology
Akira Shikuma, Daisuke Kami, Ryotaro Maeda, Yosuke Suzuki, Arata Sano, Toshihiko Taya, Takehiro Ogata, Anne Konkel, Satoaki Matoba, Wolf-Hagen Schunck, Satoshi Gojo
Summary: EEQ-A exhibits potent anti-inflammatory and immunomodulatory properties, improving survival rate and reducing organ damage in sepsis.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Chemistry, Medicinal
Lena Stiefvatter, Katja Lehnert, Konstantin Frick, Alexander Montoya-Arroyo, Jan Frank, Walter Vetter, Ulrike Schmid-Staiger, Stephan C. Bischoff
Summary: The microalgae Phaeodactylum tricornutum (PT) is a valuable source of nutrients such as proteins, polyunsaturated omega-3 fatty acids (n-3 PUFA), particularly eicosapentaenoic acid (EPA), carotenoids like fucoxanthin (FX), and beta-glucans. Intake of PT leads to an increase in n-3 PUFA and EPA levels, while also decreasing the n-6:n-3 ratio in plasma. The study shows that PT is a safe and effective source of EPA and other nutrients, suggesting its potential as a sustainable food source.
Article
Nutrition & Dietetics
Peng Wang, Kun Xiang, Yuan-Yuan Xu, Yi-Sheng He, Yu-Qian Hu, Jing Ni, Hai-Feng Pan
Summary: This study conducted Mendelian randomization analysis and found a causal relationship between genetically determined increase in omega-3 levels and increased risk for SLE. However, there was no significant causal effect of omega-6 on the risk for SLE. Additionally, there was no significant causal association between genetic predisposition to SLE and changes in omega-3 and omega-6 levels. These findings have implications for dietary recommendations.
FRONTIERS IN NUTRITION
(2022)
Article
Ecology
William R. Brignon, Martin M. Pike, Lars O. E. Ebbesson, Howard A. Schaller, James T. Peterson, Carl B. Schreck
ENVIRONMENTAL BIOLOGY OF FISHES
(2018)
Article
Fisheries
Pablo Balseiro, Oyvind Moe, Ingrid Gamlem, Munetaka Shimizu, Harald Sveier, Tom O. Nilsen, Nobuto Kaneko, Lars Ebbesson, Cindy Pedrosa, Valentina Tronci, Are Nylund, Sigurd O. Handeland
JOURNAL OF FISH BIOLOGY
(2018)
Article
Multidisciplinary Sciences
Marco A. Vindas, Stefanos Fokos, Michail Pavlidis, Erik Hoglund, Sylvia Dionysopoulou, Lars O. E. Ebbesson, Nikolaos Papandroulakis, Catherine R. Dermon
SCIENTIFIC REPORTS
(2018)
Editorial Material
Fisheries
S. D. McCormick, J. M. Shrimpton, T. O. Nilsen, L. O. Ebbesson
JOURNAL OF FISH BIOLOGY
(2018)
Article
Endocrinology & Metabolism
Athanasios Samaras, Carlos Espirito Santo, Nikos Papandroulakis, Nikolaos Mitrizakis, Michail Pavlidis, Erik Hoglund, Thamar N. M. Pelgrim, Jan Zethof, F. A. Tom Spanings, Marco A. Vindas, Lars O. E. Ebbesson, Gert Flik, Marnix Gorissen
FRONTIERS IN ENDOCRINOLOGY
(2018)
Article
Multidisciplinary Sciences
Borge Damsgard, Tor H. Evensen, Oyvind Overli, Marnix Gorissen, Lars O. E. Ebbesson, Sonia Rey, Erik Hoglund
ROYAL SOCIETY OPEN SCIENCE
(2019)
Article
Fisheries
Bernat Morro, Pablo Balseiro, Amaya Albalat, Cindy Pedrosa, Simon Mackenzie, Shu Nakamura, Munetaka Shimizu, Tom O. Nilsen, Harald Sveier, Lars O. Ebbesson, Sigurd O. Handeland
Article
Genetics & Heredity
Elsa Denker, Lars O. E. Ebbesson, David G. Hazlerigg, Daniel J. Macqueen
G3-GENES GENOMES GENETICS
(2019)
Article
Fisheries
Bernat Morro, Pablo Balseiro, Amaya Albalat, Simon Mackenzie, Cindy Pedrosa, Tom O. Nilsen, Shotaro Suzuki, Munetaka Shimizu, Harald Sveier, Marnix Gorissen, Lars O. E. Ebbesson, Sigurd O. Handeland
Article
Biology
Daan Mes, Renske van Os, Marnix Gorissen, Lars O. E. Ebbesson, Bengt Finstad, Ian Mayer, Marco A. Vindas
JOURNAL OF EXPERIMENTAL BIOLOGY
(2019)
Article
Fisheries
Trine Ytrestoyl, Harald Takle, Jelena Kolarevic, Sara Calabrese, Gerrit Timmerhaus, Bjorn O. Rosseland, Hans C. Teien, Tom O. Nilsen, Sigurd O. Handeland, Sigurd O. Stefansson, Lars O. E. Ebbesson, Bendik F. Terjesen
JOURNAL OF THE WORLD AQUACULTURE SOCIETY
(2020)
Article
Multidisciplinary Sciences
Mariann Eilertsen, Benjamin G. J. Clokie, Lars O. E. Ebbesson, Cristina Tanase, Herve Migaud, Jon Vidar Helvik
Summary: Photoreceptive inputs to the teleost brain are perceived as images of the visual world and modulation of neuroendocrine and neuronal signals. This study tested the effects of narrow bandwidth light on brain neural activity in Atlantic salmon, revealing an increase in c-fos expression and activation of specific brain regions following light stimulation. The overlapping expression patterns of c-fos and nonvisual opsins suggest a direct light stimulation of deep brain photoreceptors.
Article
Biochemistry & Molecular Biology
Wenda Cui, Eisuke Takahashi, Bernat Morro, Pablo Balseiro, Amaya Albalat, Cindy Pedrosa, Simon Mackenzie, Tom O. Nilsen, Harald Sveier, Lars O. Ebbesson, Sigurd O. Handeland, Munetaka Shimizu
Summary: The process of smoltification in salmonids, such as rainbow trout, occurs during spring in response to increasing photoperiod to prepare for marine life. This process is associated with increased hypo-osmoregulatory ability and enhanced growth potential, mediated by growth hormone and insulin-like growth factor (IGF)-1. However, rainbow trout is unique in its insensitivity to photoperiod-induced smoltification-associated changes. This study found that circulating IGF-1 and IGF-binding protein (IGFBP)-2b levels were positively correlated with gill Na+,K+-ATPase (NKA) activity in rainbow trout exposed to natural photoperiod. The study also found that the size-dependent activation of gill NKA in yearling rainbow trout during spring is mediated by circulating IGFBP-2b and IGF-1.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY
(2022)
Article
Environmental Sciences
P. A. Tang, N. Gharbi, T. O. Nilsen, M. Gorissen, S. O. Stefansson, L. O. E. Ebbesson
Summary: The successful transfer of farmed post-smolt Atlantic salmon depends on stress responses and cognitive functions, which may be challenged by increasing oceanic temperatures. This study examined the effects of transferring fish to different temperatures on stress responses and cognitive gene expression. The results showed that lower temperatures maintained normal stress responses, while higher temperatures inhibited stress responses and cognitive functions.
FRONTIERS IN MARINE SCIENCE
(2022)
Article
Fisheries
P. A. Tang, S. O. Stefansson, T. O. Nilsen, N. Gharbi, F. Lai, V Tronci, P. Balseiro, M. Gorissen, L. O. E. Ebbesson
Summary: The neural adaptions of post-smolt Atlantic salmon to cold water temperatures impact their stress resilience. Abruptly transferring post-smolt to lower temperatures resulted in altered telencephalic functions and reduced stress response capacities. However, after acclimation and prolonged exposure to lower temperatures, some level of stress resilience is still maintained.
