Glucosamine Activates Autophagy In Vitro and In Vivo

Effects of aging on articular cartilage homeostasis

(2012) Martin Lotz et al.   BONE

Is there any scientific evidence for the use of glucosamine in the management of human osteoarthritis?

(2012) Yves Henrotin et al.   ARTHRITIS RESEARCH & THERAPY

Recent progress in understanding molecular mechanisms of cartilage degeneration during osteoarthritis

(2011) Meina Wang et al.   Annals of the New York Academy of Sciences

Autophagy activation by rapamycin reduces severity of experimental osteoarthritis

(2011) Beatriz Caramés et al.   ANNALS OF THE RHEUMATIC DISEASES

Mechanical injury suppresses autophagy regulators and pharmacologic activation of autophagy results in chondroprotection

(2011) Beatriz Caramés et al.   ARTHRITIS AND RHEUMATISM

The epigenetic effect of glucosamine and a nuclear factor-kappa B (NF-kB) inhibitor on primary human chondrocytes – Implications for osteoarthritis

(2011) Kei Imagawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Autophagy and Aging

(2011) David C. Rubinsztein et al.   CELL

Mammalian Target of Rapamycin (mTOR) Inhibitors

(2011) Sofia Sofroniadou et al.   DRUG SAFETY

Long-term oral administration of glucosamine or chondroitin sulfate reduces destruction of cartilage and up-regulation of MMP-3 mRNA in a model of spontaneous osteoarthritis in Hartley guinea pigs

(2011) Shin Taniguchi et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

The role of mitochondria in osteoarthritis

(2011) Francisco J. Blanco et al.   Nature Reviews Rheumatology

Use of complementary and alternative medicine among patients with radiographic-confirmed knee osteoarthritis

(2011) K.L. Lapane et al.   OSTEOARTHRITIS AND CARTILAGE

Mitochondria and the Autophagy-Inflammation-Cell Death Axis in Organismal Aging

(2011) D. R. Green et al.   SCIENCE

Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis

(2010) Beatriz Caramés et al.   ARTHRITIS AND RHEUMATISM

Short-term fasting induces profound neuronal autophagy

(2010) Mehrdad Alirezaei et al.   Autophagy

Glucosamine induces autophagy via an mTOR-independent pathway

(2010) Tomoya Shintani et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

Epidemiology of Osteoarthritis

(2010) Yuqing Zhang et al.   CLINICS IN GERIATRIC MEDICINE

The Complexes of Mammalian Target of Rapamycin

(2010) Hongyu Zhou et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

A comprehensive review of oral glucosamine use and effects on glucose metabolism in normal and diabetic individuals

(2010) R. R. Simon et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Functions and regulation of the 70kDa ribosomal S6 kinases

(2010) Tim R. Fenton et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Pharmacologic therapy for osteoarthritis—the era of disease modification

(2010) David J. Hunter   Nature Reviews Rheumatology

Inhibitors of mTOR

(2010) H.-J. Klumpen et al.   ONCOLOGIST

Glucosamine sulfate reduces experimental osteoarthritis and nociception in rats: association with changes of mitogen-activated protein kinase in chondrocytes

(2010) Z.-H. Wen et al.   OSTEOARTHRITIS AND CARTILAGE

OARSI recommendations for the management of hip and knee osteoarthritis

(2010) W. Zhang et al.   OSTEOARTHRITIS AND CARTILAGE

Aging and osteoarthritis: the role of chondrocyte senescence and aging changes in the cartilage matrix

(2009) R.F. Loeser   OSTEOARTHRITIS AND CARTILAGE

OA clinical trials: current targets and trials for OA. Choosing molecular targets: what have we learned and where we are headed?

(2009) M.-P. Hellio Le Graverand-Gastineau   OSTEOARTHRITIS AND CARTILAGE

The effects of oral glucosamine on joint health: is a change in research approach needed?

(2009) J.A. Block et al.   OSTEOARTHRITIS AND CARTILAGE

The human pharmacokinetics of oral ingestion of glucosamine and chondroitin sulfate taken separately or in combination

(2009) C.G. Jackson et al.   OSTEOARTHRITIS AND CARTILAGE

Glucosamine therapy for knee osteoarthritis: pharmacokinetic considerations

(2009) Roy D Altman   Expert Review of Clinical Pharmacology