An update of human mesenchymal stem cell biology and their clinical uses
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
An update of human mesenchymal stem cell biology and their clinical uses
Authors
Keywords
Adipogenesis, Bone, Osteogenesis, Stromal stem cells, Regenerative medicine
Journal
ARCHIVES OF TOXICOLOGY
Volume 88, Issue 5, Pages 1069-1082
Publisher
Springer Nature
Online
2014-04-01
DOI
10.1007/s00204-014-1232-8
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The Safety of Embryonic Stem Cell Therapy Relies on Teratoma Removal
- (2015) Oncotarget
- Glycogen synthase kinase 3 alpha phosphorylates and regulates the osteogenic activity of Osterix
- (2013) Hongyan Li et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Calmodulin-dependent kinase II regulates osteoblast differentiation through regulation of Osterix
- (2013) You Hee Choi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Lipin1 regulates PPARγ transcriptional activity
- (2013) Hee Eun Kim et al. BIOCHEMICAL JOURNAL
- MicroRNA-214 suppresses osteogenic differentiation of C2C12 myoblast cells by targeting Osterix
- (2013) Kaikai Shi et al. BONE
- Adipocytes and the Regulation of Bone Remodeling: A Balancing Act
- (2013) Mark E. Nuttall et al. CALCIFIED TISSUE INTERNATIONAL
- Transcription factor Snail is a novel regulator of adipocyte differentiation via inhibiting the expression of peroxisome proliferator-activated receptor γ
- (2013) Yong-ho Lee et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Maternal Obesity Enhances White Adipose Tissue Differentiation and Alters Genome-Scale DNA Methylation in Male Rat Offspring
- (2013) Sarah J. Borengasser et al. ENDOCRINOLOGY
- ESET histone methyltransferase regulates osteoblastic differentiation of mesenchymal stem cells during postnatal bone development
- (2013) Kevin A. Lawson et al. FEBS LETTERS
- miR-145 suppresses osteogenic differentiation by targeting Sp7
- (2013) Jie Jia et al. FEBS LETTERS
- Genetic instability in human embryonic stem cells: prospects and caveats
- (2013) Thierry Nouspikel Future Oncology
- Histone Demethylase Jmjd3 Regulates Osteoblast Differentiation via Transcription FactorsRunx2and Osterix
- (2013) Di Yang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MicroRNA-322 (miR-322) and Its Target Protein Tob2 Modulate Osterix (Osx) mRNA Stability
- (2013) Beatriz Gámez et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PCAF acetylates Runx2 and promotes osteoblast differentiation
- (2013) Chao-Yang Wang et al. JOURNAL OF BONE AND MINERAL METABOLISM
- Glucocorticoids Antagonize RUNX2 During Osteoblast Differentiation in Cultures of ST2 Pluripotent Mesenchymal Cells
- (2013) Theodora Koromila et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Regulation of the osterix (Osx, Sp7) promoter by osterix and its inhibition by parathyroid hormone
- (2013) Richard Barbuto et al. JOURNAL OF MOLECULAR ENDOCRINOLOGY
- The meaning, the sense and the significance: translating the science of mesenchymal stem cells into medicine
- (2013) Paolo Bianco et al. NATURE MEDICINE
- Characterization of Osterix Protein Stability and Physiological Role in Osteoblast Differentiation
- (2013) Yanyan Peng et al. PLoS One
- E3 Ubiquitin Ligase E6AP Negatively Regulates Adipogenesis by Downregulating Proadipogenic Factor C/EBPalpha
- (2013) Pooja Pal et al. PLoS One
- Treatment of Knee Osteoarthritis With Autologous Mesenchymal Stem Cells
- (2013) Lluis Orozco et al. TRANSPLANTATION
- Dexamethasone shifts bone marrow stromal cells from osteoblasts to adipocytes by C/EBPalpha promoter methylation
- (2013) J Li et al. Cell Death & Disease
- Redundant miR-3077-5p and miR-705 mediate the shift of mesenchymal stem cell lineage commitment to adipocyte in osteoporosis bone marrow
- (2013) L Liao et al. Cell Death & Disease
- Arid5b facilitates chondrogenesis by recruiting the histone demethylase Phf2 to Sox9-regulated genes
- (2013) Kenji Hata et al. Nature Communications
- Prospective Isolation of Murine and Human Bone Marrow Mesenchymal Stem Cells Based on Surface Markers
- (2013) Yo Mabuchi et al. Stem Cells International
- Adult Bone Marrow Cell Therapy Improves Survival and Induces Long-Term Improvement in Cardiac Parameters
- (2012) Vinodh Jeevanantham et al. CIRCULATION
- L-Sox5 and Sox6 Proteins Enhance Chondrogenic miR-140 MicroRNA Expression by Strengthening Dimeric Sox9 Activity
- (2012) Satoshi Yamashita et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Basic Helix-Loop-Helix Transcription Factor Twist1 Inhibits Transactivator Function of Master Chondrogenic Regulator Sox9
- (2012) Shoujun Gu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- miR-93/Sp7 function loop mediates osteoblast mineralization
- (2012) Li Yang et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Notch gain of function inhibits chondrocyte differentiation via Rbpj-dependent suppression ofSox9
- (2012) Shan Chen et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Genetic and molecular control of osterix in skeletal formation
- (2012) Krishna M. Sinha et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Lessons from human teratomas to guide development of safe stem cell therapies
- (2012) Justine J Cunningham et al. NATURE BIOTECHNOLOGY
- Isolation of mouse mesenchymal stem cells on the basis of expression of Sca-1 and PDGFR-α
- (2012) Diarmaid D Houlihan et al. Nature Protocols
- One-Step Derivation of Mesenchymal Stem Cell (MSC)-Like Cells from Human Pluripotent Stem Cells on a Fibrillar Collagen Coating
- (2012) Yongxing Liu et al. PLoS One
- The Adult Human Brain Harbors Multipotent Perivascular Mesenchymal Stem Cells
- (2012) Gesine Paul et al. PLoS One
- Human Stromal (Mesenchymal) Stem Cells from Bone Marrow, Adipose Tissue and Skin Exhibit Differences in Molecular Phenotype and Differentiation Potential
- (2012) May Al-Nbaheen et al. Stem Cell Reviews and Reports
- Derivation of Stromal (Skeletal and Mesenchymal) Stem-Like Cells from Human Embryonic Stem Cells
- (2012) Amer Mahmood et al. STEM CELLS AND DEVELOPMENT
- Silencing of microRNA-101 prevents IL-1β-induced extracellular matrix degradation in chondrocytes
- (2012) Linghui Dai et al. ARTHRITIS RESEARCH & THERAPY
- Consecutive Positive Feedback Loops Create a Bistable Switch that Controls Preadipocyte-to-Adipocyte Conversion
- (2012) Byung Ouk Park et al. Cell Reports
- Mesenchymal Stem Cells Isolated from Adipose and Other Tissues: Basic Biological Properties and Clinical Applications
- (2012) Hakan Orbay et al. Stem Cells International
- Safety of Mesenchymal Stem Cells for Clinical Application
- (2012) Youwei Wang et al. Stem Cells International
- Senescence-associated intrinsic mechanisms of osteoblast dysfunctions
- (2011) Moustapha Kassem et al. AGING CELL
- miR-125b Regulates Calcification of Vascular Smooth Muscle Cells
- (2011) Claudia Goettsch et al. AMERICAN JOURNAL OF PATHOLOGY
- Osterix is regulated by Erk1/2 during osteoblast differentiation
- (2011) You Hee Choi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Akt phosphorylates and regulates the osteogenic activity of Osterix
- (2011) You Hee Choi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Anti-inflammatory protein TSG-6 secreted by activated MSCs attenuates zymosan-induced mouse peritonitis by decreasing TLR2/NF- B signaling in resident macrophages
- (2011) H. Choi et al. BLOOD
- CD146 expression on primary nonhematopoietic bone marrow stem cells is correlated with in situ localization
- (2011) A. Tormin et al. BLOOD
- Short- and long-term outcomes of intracoronary and endogenously mobilized bone marrow stem cells in the treatment of ST-segment elevation myocardial infarction: a meta-analysis of randomized control trials
- (2011) Hendrik Zimmet et al. EUROPEAN JOURNAL OF HEART FAILURE
- Allogeneic mesenchymal stem cell transplantation in seven patients with refractory inflammatory bowel disease
- (2011) Jun Liang et al. GUT
- Regulation of Human Chondrocyte Function through Direct Inhibition of Cartilage Master Regulator SOX9 by MicroRNA-145 (miRNA-145)
- (2011) Aida Martinez-Sanchez et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Unraveling the transcriptional regulatory machinery in chondrogenesis
- (2011) Haruhiko Akiyama et al. JOURNAL OF BONE AND MINERAL METABOLISM
- Global Cardiovascular Health
- (2011) Valentin Fuster et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- MiR-637 maintains the balance between adipocytes and osteoblasts by directly targeting Osterix
- (2011) Jin-fang Zhang et al. MOLECULAR BIOLOGY OF THE CELL
- Encapsulated native and glucagon-like peptide-1 transfected human mesenchymal stem cells in a transgenic mouse model of Alzheimer's disease
- (2011) Petra M. Klinge et al. NEUROSCIENCE LETTERS
- Radiation Rescue: Mesenchymal Stromal Cells Protect from Lethal Irradiation
- (2011) Claudia Lange et al. PLoS One
- MicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo
- (2011) T. Eskildsen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Coexpression of VEGF and angiopoietin-1 promotes angiogenesis and cardiomyocyte proliferation reduces apoptosis in porcine myocardial infarction (MI) heart
- (2011) Zhengxian Tao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MiRNA-20a promotes osteogenic differentiation of human mesenchymal stem cells by co-regulating BMP signaling
- (2011) Jin-fang Zhang et al. RNA Biology
- The Role of Chemokines in Mesenchymal Stem Cell Homing to Myocardium
- (2011) Yaojiong Wu et al. Stem Cell Reviews and Reports
- Selective Removal of Undifferentiated Human Embryonic Stem Cells Using Magnetic Activated Cell Sorting Followed by a Cytotoxic Antibody
- (2011) Kornelia Schriebl et al. TISSUE ENGINEERING PART A
- SOX9 Governs Differentiation Stage-Specific Gene Expression in Growth Plate Chondrocytes via Direct Concomitant Transactivation and Repression
- (2011) Victor Y. L. Leung et al. PLoS Genetics
- Mesenchymal stem cells as therapeutics and vehicles for gene and drug delivery
- (2010) Christopher D. Porada et al. ADVANCED DRUG DELIVERY REVIEWS
- Autologous Bone Marrow–Derived Mesenchymal Stem Cells Versus Autologous Chondrocyte Implantation
- (2010) Hossein Nejadnik et al. AMERICAN JOURNAL OF SPORTS MEDICINE
- Engineered mesenchymal stem cells with self-assembled vesicles for systemic cell targeting
- (2010) Debanjan Sarkar et al. BIOMATERIALS
- Selective isolation and differentiation of a stromal population of human embryonic stem cells with osteogenic potential
- (2010) Linda Harkness et al. BONE
- Mesenchymal stem cell as salvage treatment for refractory chronic GVHD
- (2010) J Y Weng et al. BONE MARROW TRANSPLANTATION
- Functional Mesenchymal Stem Cells Derived From Human Induced Pluripotent Stem Cells Attenuate Limb Ischemia in Mice
- (2010) Qizhou Lian et al. CIRCULATION
- Genetic Modification of Mesenchymal Stem Cells Overexpressing CCR1 Increases Cell Viability, Migration, Engraftment, and Capillary Density in the Injured Myocardium
- (2010) Jing Huang et al. CIRCULATION RESEARCH
- Bone Marrow Mesenchymal Stem Cells Stimulate Cardiac Stem Cell Proliferation and Differentiation
- (2010) Konstantinos E. Hatzistergos et al. CIRCULATION RESEARCH
- Autologous bone marrow-derived mesenchymal stromal cell treatment for refractory luminal Crohn's disease: results of a phase I study
- (2010) Marjolijn Duijvestein et al. GUT
- p38 Regulates Expression of Osteoblast-specific Genes by Phosphorylation of Osterix
- (2010) María José Ortuño et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- 1,25-dihydroxyvitamin D3 potentiates fluoride-stimulated collagen type I production in cultures of human bone marrow stromal osteoblast-like cells
- (2010) Moustapha Kassem et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Enhanced differentiation of human embryonic stem cells to mesenchymal progenitors by inhibition of TGF-β/activin/nodal signaling using SB-431542
- (2010) Amer Mahmood et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Paracrine mechanisms of stem cell reparative and regenerative actions in the heart
- (2010) Maria Mirotsou et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Mesenchymal Stem Cells Expressing Osteogenic and Angiogenic Factors Synergistically Enhance Bone Formation in a Mouse Model of Segmental Bone Defect
- (2010) Sanjay Kumar et al. MOLECULAR THERAPY
- Identification of SOX9 Interaction Sites in the Genome of Chondrocytes
- (2010) Chun-do Oh et al. PLoS One
- Mapping the first stages of mesoderm commitment during differentiation of human embryonic stem cells
- (2010) D. Evseenko et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A circadian-regulated gene, Nocturnin, promotes adipogenesis by stimulating PPAR- nuclear translocation
- (2010) M. Kawai et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Changes in left ventricular filling patterns after repeated injection of autologous bone marrow cells in heart failure patients
- (2010) Axel C. P. Diederichsen et al. SCANDINAVIAN CARDIOVASCULAR JOURNAL
- Osteogenic Potential of Human Mesenchymal Stem Cells and Human Embryonic Stem Cell-Derived Mesodermal Progenitors: A Tissue Engineering Perspective
- (2010) Giuseppe Maria de Peppo et al. TISSUE ENGINEERING PART A
- Adult Human Mesenchymal Stem Cells Added to Corticosteroid Therapy for the Treatment of Acute Graft-versus-Host Disease
- (2009) Partow Kebriaei et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Mesenchymal Stem Cell Homing: The Devil Is in the Details
- (2009) Jeffrey M. Karp et al. Cell Stem Cell
- Combined Treatment of Intrapancreatic Autologous Bone Marrow Stem Cells and Hyperbaric Oxygen in Type 2 Diabetes Mellitus
- (2009) Esteban J. Estrada et al. CELL TRANSPLANTATION
- A Pilot Trial to Assess Potential Effects of Selective Intracoronary Bone Marrow–Derived Progenitor Cell Infusion in Patients With Nonischemic Dilated Cardiomyopathy
- (2009) Ulrich Fischer-Rasokat et al. Circulation-Heart Failure
- Molecular switching of osteoblastogenesis versus adipogenesis: implications for targeted therapies
- (2009) Ichiro Takada et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- A Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation Study of Intravenous Adult Human Mesenchymal Stem Cells (Prochymal) After Acute Myocardial Infarction
- (2009) Joshua M. Hare et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Variation in the safety of induced pluripotent stem cell lines
- (2009) Kyoko Miura et al. NATURE BIOTECHNOLOGY
- Wnt and PPARγ signaling in osteoblastogenesis and adipogenesis
- (2009) Ichiro Takada et al. Nature Reviews Rheumatology
- Cerebral transplantation of encapsulated mesenchymal stem cells improves cellular pathology after experimental traumatic brain injury
- (2009) Anna M.B. Heile et al. NEUROSCIENCE LETTERS
- Teratoma formation by human embryonic stem cells: Evaluation of essential parameters for future safety studies
- (2009) Hannes Hentze et al. Stem Cell Research
- Efficacy of Autologous Bone Marrow–Derived Stem Cell Transplantation in Patients With Type 2 Diabetes Mellitus
- (2009) Anil Bhansali et al. STEM CELLS AND DEVELOPMENT
- Immunomodulatory Properties of Mesenchymal Stromal Cells and Their Therapeutic Consequences for Immune-Mediated Disorders
- (2009) Senming Zhao et al. STEM CELLS AND DEVELOPMENT
- MicroRNA hsa-miR-135b Regulates Mineralization in Osteogenic Differentiation of Human Unrestricted Somatic Stem Cells
- (2009) Aneta M. Schaap-Oziemlak et al. STEM CELLS AND DEVELOPMENT
- Human Embryonic Stem Cell–Derived Mesoderm-like Epithelium Transitions to Mesenchymal Progenitor Cells
- (2009) Nolan L. Boyd et al. TISSUE ENGINEERING PART A
- Transcription factors controlling osteoblastogenesis
- (2008) Pierre J. Marie ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- The Derivation of Mesenchymal Stem Cells from Human Embryonic Stem Cells
- (2008) Shelley E. Brown et al. CELLS TISSUES ORGANS
- Paracrine Mechanisms in Adult Stem Cell Signaling and Therapy
- (2008) Massimiliano Gnecchi et al. CIRCULATION RESEARCH
- IGF-1–Overexpressing Mesenchymal Stem Cells Accelerate Bone Marrow Stem Cell Mobilization via Paracrine Activation of SDF-1α/CXCR4 Signaling to Promote Myocardial Repair
- (2008) Husnain Kh Haider et al. CIRCULATION RESEARCH
- Virtual karyotyping with SNP microarrays reduces uncertainty in the diagnosis of renal epithelial tumors
- (2008) Jill M Hagenkord et al. Diagnostic Pathology
- Characterization of the paracrine effects of human skeletal myoblasts transplanted in infarcted myocardium
- (2008) Maitane Perez-Ilzarbe et al. EUROPEAN JOURNAL OF HEART FAILURE
- Controversial issue: Is it safe to employ mesenchymal stem cells in cell-based therapies?
- (2008) Günter Lepperdinger et al. EXPERIMENTAL GERONTOLOGY
- Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study
- (2008) Katarina Le Blanc et al. LANCET
- Efficient tumour formation by single human melanoma cells
- (2008) Elsa Quintana et al. NATURE
- Characterization and Genetic Manipulation of Human Umbilical Cord Vein Mesenchymal Stem Cells: Potential Application in Cell-Based Gene Therapy
- (2008) Abbas Jafari Kermani et al. REJUVENATION RESEARCH
- Bone Tissue Formation from Human Embryonic Stem Cells In Vivo
- (2008) J.L. Tremoleda et al. Cloning Stem Cells
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now