Notch gain of function inhibits chondrocyte differentiation via Rbpj-dependent suppression ofSox9

Notch1 signaling regulates chondrogenic lineage determination through Sox9 activation

(2011) R Haller et al.   CELL DEATH AND DIFFERENTIATION

Sox9 sustains chondrocyte survival and hypertrophy in part through Pik3ca-Akt pathways

(2011) D. Ikegami et al.   DEVELOPMENT

Mutations in NOTCH2 in families with Hajdu-Cheney syndrome

(2011) Jacek Majewski et al.   HUMAN MUTATION

Notch post-translationally regulates β-catenin protein in stem and progenitor cells

(2011) Chulan Kwon et al.   NATURE CELL BIOLOGY

Truncating mutations in the last exon of NOTCH2 cause a rare skeletal disorder with osteoporosis

(2011) Bertrand Isidor et al.   NATURE GENETICS

Alteration of Notch signaling in skeletal development and disease

(2010) Jianning Tao et al.   Annals of the New York Academy of Sciences

Signaling Pathways in Human Skeletal Dysplasias

(2010) Dustin Baldridge et al.   Annual Review of Genomics and Human Genetics

Metamotifs - a generative model for building families of nucleotide position weight matrices

(2010) Matias Piipari et al.   BMC BIOINFORMATICS

Non-canonical activation of Notch signaling/target genes in vertebrates

(2010) Rajendran Sanalkumar et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

RBPj -dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal development

(2010) Y. Dong et al.   DEVELOPMENT

Osteosclerosis owing to Notch gain of function is solely Rbpj-dependent

(2010) Jianning Tao et al.   JOURNAL OF BONE AND MINERAL RESEARCH

E-selectin ligand–1 regulates growth plate homeostasis in mice by inhibiting the intracellular processing and secretion of mature TGF-β

(2010) Tao Yang et al.   JOURNAL OF CLINICAL INVESTIGATION

Activated Notch1 Target Genes during Embryonic Cell Differentiation Depend on the Cellular Context and Include Lineage Determinants and Inhibitors

(2010) Franziska Meier-Stiegen et al.   PLoS One

Notch signaling controls liver development by regulating biliary differentiation

(2009) Y. Zong et al.   DEVELOPMENT

Long-range regulation at the SOX9 locus in development and disease

(2009) C T Gordon et al.   JOURNAL OF MEDICAL GENETICS

Notch and the Skeleton

(2009) S. Zanotti et al.   MOLECULAR AND CELLULAR BIOLOGY

Use of in vivo biotinylation to study protein–protein and protein–DNA interactions in mouse embryonic stem cells

(2009) Jonghwan Kim et al.   Nature Protocols

Notch pathway regulation of chondrocyte differentiation and proliferation during appendicular and axial skeleton development

(2009) T. J. Mead et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sox9, a key transcription factor of bone morphogenetic protein-2-induced chondrogenesis, is activated through BMP pathway and a CCAAT box in the proximal promoter

(2008) Qiuhui Pan et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Regulation of chondrogenesis and chondrocyte differentiation by stress

(2008) Michael J. Zuscik et al.   JOURNAL OF CLINICAL INVESTIGATION

Control of chondrogenesis by the transcription factor Sox9

(2008) Haruhiko Akiyama   Modern Rheumatology

Dimorphic effects of Notch signaling in bone homeostasis

(2008) Feyza Engin et al.   NATURE MEDICINE

Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation

(2008) Matthew J Hilton et al.   NATURE MEDICINE

Notch-Deficient Skin Induces a Lethal Systemic B-Lymphoproliferative Disorder by Secreting TSLP, a Sentinel for Epidermal Integrity

(2008) Shadmehr Demehri et al.   PLOS BIOLOGY