Screening of chemicals for human bioaccumulative potential with a physiologically based toxicokinetic model

Comparison of metabolic stability and metabolite identification of 55 ECVAM/ICCVAM validation compounds between human and rat liver homogenates and microsomes - a preliminary analysis

(2016) Olavi Pelkonen   ALTEX-Alternatives to Animal Experimentation

Alternative (non-animal) methods for cosmetics testing: current status and future prospects—2010

(2011) Sarah Adler et al.   ARCHIVES OF TOXICOLOGY

Associations of fat mass and lean mass with bone mineral density differ by levels of persistent organic pollutants: National Health and Nutrition Examination Survey 1999–2004

(2011) M.-R. Cho et al.   CHEMOSPHERE

Modeling bioaccumulation in humans using poly-parameter linear free energy relationships (PPLFERS)

(2011) Emma Undeman et al.   SCIENCE OF THE TOTAL ENVIRONMENT

A Model-Based Prioritisation Exercise for the European Water Framework Directive

(2011) Klaus Daginnus et al.   International Journal of Environmental Research and Public Health

An integrated approach for bioaccumulation assessment in mussels: Towards the development of Environmental Quality Standards for biota

(2010) J.M. Zaldívar et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Bioaccumulation of Organic Contaminants in Humans: A Multimedia Perspective and the Importance of Biotransformation†

(2010) Michael S. McLachlan et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Human Blood Concentrations of Dichlorodiphenyltrichloroethane (DDT) Extrapolated from Metabolism in Rats and Humans and Physiologically Based Pharmacokinetic Modeling

(2010) Hiroshi Yamazaki et al.   JOURNAL OF HEALTH SCIENCE

Evaluation and prediction of pharmacokinetics of PFOA and PFOS in the monkey and human using a PBPK model

(2010) Anne E. Loccisano et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Incorporating Human Dosimetry and Exposure into High-Throughput In Vitro Toxicity Screening

(2010) Daniel M. Rotroff et al.   TOXICOLOGICAL SCIENCES

Physiologically based mechanistic modelling to predict complex drug–drug interactions involving simultaneous competitive and time-dependent enzyme inhibition by parent compound and its metabolite in both liver and gut—The effect of diltiazem on the time-course of exposure to triazolam

(2009) Karen Rowland Yeo et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

The Simcyp®Population-based ADME Simulator

(2009) Masoud Jamei et al.   Expert Opinion on Drug Metabolism & Toxicology

A bioaccumulation model for herbicides in Ulva rigida and Tapes philippinarum in Sacca di Goro lagoon (Northern Adriatic)

(2008) Roberta Carafa et al.   CHEMOSPHERE

ESTIMATING METABOLIC BIOTRANSFORMATION RATES IN FISH FROM LABORATORY DATA

(2008) Jon A. Arnot et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Validation of a Rapid Equilibrium Dialysis Approach for the Measurement of Plasma Protein Binding

(2008) Nigel J. Waters et al.   JOURNAL OF PHARMACEUTICAL SCIENCES