4.7 Article

Magnetic Purification of Curcumin from Curcuma longa Rhizome by Novel Naked Maghemite Nanoparticles

Journal

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Volume 63, Issue 3, Pages 912-920

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jf504624u

Keywords

magnetic purification; curcumin; Curcuma longa; curcuminoids; magnetic nanoparticles; polyphenols

Funding

  1. Fondazione CARIPARO
  2. Italian Institutional Ministry Grants [60A06-7411, 60A06-8055]

Ask authors/readers for more resources

Naked maghemite nanoparticles, namely, surface active maghemite nanoparticles (SAMNs), characterized by a diameter of about 10 nm, possessing peculiar colloidal stability, surface chemistry, and superparamagnetism, present fundamental requisites for the development of effective magnetic purification processes for biomolecules in complex matrices. Polyphenolic molecules presenting functionalities with different proclivities toward iron chelation were studied as probes for testing SAMN suitability for magnetic purification. Thus, the binding efficiency and reversibility on SAMNs of phenolic compounds of interest in the pharmaceutical and food industries, namely, catechin, tyrosine, hydroxytyrosine, ferulic acid, coumaric acid, rosmarinic acid, naringenin, curcumin, and cyanidin-3-glucoside, were evaluated. Curcumin emerged as an elective compound, suitable for magnetic purification by SAMNs from complex matrices. A combination of curcumin, demethoxycurcumin, and bis-demethoxycurcumin was recovered by a single magnetic purification step from extracts of Curcuma longa rhizomes, with a purity >98% and a purification yield of 45%, curcumin being >80% of the total purified curcuminoids.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.7
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

Article Horticulture

Improvement of biogenic amines in grape juice from Vitis labrusca and hybrid grapes grown in different training systems

Francisco Jose Domingues Neto, Cristine Vanz Borges, Giuseppina Pace Pereira Lima, Adilson Pimentel Junior, Gean Charles Monteiro, Ricardo Figueira, Waldemar Gastoni Venturini Filho, Igor Otavio Minatel, Mara Fernandes Moura, Marco Antonio Tecchio

Summary: This study quantified the biogenic amines and antioxidant activity in different varieties of grapes in Brazil. The results showed that the training system and genotype had an impact on the presence of amino compounds and antioxidants. It is recommended to use a high vertical shoot position system to improve certain biogenic amine levels.

JOURNAL OF HORTICULTURAL SCIENCE & BIOTECHNOLOGY (2023)

Article Cardiac & Cardiovascular Systems

Fructose Consumption Alters Biogenic Amines Associated with Cardiovascular Disease Risk Factors

Fabiane Valentini Francisqueti-Ferron, Matheus Antonio Filiol Belin, Thiago Luiz Novaga Palacio, Artur Junio Togneri Ferron, Jessica Leite Garcia, Juliana Silva Siqueira, Erika Tiemi Nakandakare-Maia, Taynara Aparecida Vieira, Hugo Tadashi Kano, Fernando Moreto, Giuseppina Pace Pereira Lima, Camila Renata Correa, Igor Otavio Minatel

Summary: This study aimed to investigate the association between fructose consumption and biogenic amine (BA) levels, as well as the relationship with cardiovascular disease (CVD) risk factors. The results showed that fructose consumption led to metabolic syndrome, reduced tryptophan and 5-hydroxitryptophan levels, and increased histamine levels. Tryptophan, histamine, and dopamine were correlated with metabolic syndrome parameters.

ARQUIVOS BRASILEIROS DE CARDIOLOGIA (2023)

Article Chemistry, Applied

Biogenic amines and stable isotopes in the quality and authenticity of honeys from Brazil

Giuseppina Pace Pereira Lima, Vladmir Eliodoro Costa, Aline Nunes, Leticia Silva Pereira Basilio, Cristine Vanz Borges, Gean Charles Monteiro, Igor Otavio Minatel, Juliana Celia Denadai, Ricardo Orsi, Fabio Vianello, Marcelo Maraschin

Summary: This study conducted the identification of biogenic amines and some precursor amino acids in 114 honey samples from different regions in Brazil, as well as the detection of honey adulteration through stable isotopes. The results showed the presence of serotonin in all samples, and melatonin in the majority of honey. Higher levels of L-Dopa, dopamine, and histamine were found in honey from certain regions. The stable isotope technique was crucial in detecting adulterated honey.

FOOD CHEMISTRY (2023)

Article Engineering, Environmental

Mechanistic insights into Pb and sulfates retention in ordinary Portland cement and aluminous cement: Assessing the contributions from binders and solid waste

Yikai Liu, Simone Molinari, Maria Chiara Dalconi, Luca Valentini, Maurizio Pietro Bellotto, Giorgio Ferrari, Roberto Pellay, Graziano Rilievo, Fabio Vianello, Gabriella Salviulo, Qiusong Chen, Gilberto Artioli

Summary: A geochemical model combined with parametric fitting techniques was used to investigate the solidification/stabilization mechanisms of Pb-rich pyrite ash in ordinary Portland cement and calcium aluminate cement. The study revealed that ettringite and calcium silicate hydrates have strong affinities for Pb under alkaline conditions. When the hydration products are unable to stabilize all the soluble Pb, part of it may be immobilized as Pb(OH)2. Hematite from pyrite ash and newly-formed ferrihydrite, along with anglesite and cerussite precipitation, are the main controlling factors of Pb under acidic and neutral conditions. This work provides valuable insights for the development of more sustainable mixture formulations in solid waste remediation.

JOURNAL OF HAZARDOUS MATERIALS (2023)

Article Biochemistry & Molecular Biology

Impact of Agronomic Treatments on the Enzymatic Browning of Eggplants (Solanum melongena L.)

Peyman Ebrahimi, Carlo Nicoletto, Paolo Sambo, Federica Tinello, Dasha Mihaylova, Anna Lante

Summary: This study evaluated the effect of fertilization techniques and grafting on polyphenol oxidase (PPO) activity and colorimetric parameters in cultivated eggplants. Fertilization alone significantly increased PPO activity, while fertilization combined with grafting decreased PPO activity. There was a significant positive correlation between PPO activity and the a* values of the eggplants. Additionally, eggplant slices exposed to room temperature for 60 minutes showed a significant increase in PPO activity and color parameters.

ANTIOXIDANTS (2023)

Article Horticulture

Profile of Bioactive Compounds in Orange Juice Related to the Combination of Different Scion/Rootstocks, Packaging and Storage

Rafaelly Calsavara Martins, Sarita Leonel, Jackson Mirellys Azevedo Souza, Giuseppina Pace Pereira Lima, Magali Leonel, Fernando Ferrari Putti, Gean Charles Monteiro, Patricia Graosque uelguim Zuge, Gabriel Maluf Napoleao, Ricardo Figueira, Jaime Duarte Filho

Summary: The concentrations of bioactive compounds in orange juice are affected by different citrus scion/rootstock combinations. Packaging and storage can optimize the shelf life of freshly squeezed juice. The combination of 'Rubi' orange in both 'Rangpur' lime and 'Swingle' citrumelo rootstocks showed higher concentrations of ascorbic acid and dehydroascorbic acid. Overall, scions grafted onto 'Swingle' citrumelo rootstock had higher concentrations of ascorbic acid, dehydroascorbic acid, and some phenolic compounds. Phenolic compounds had the highest concentrations at the time of fruit extraction and decreased during storage. Dark packaging increased the levels of bioactive compounds in juices stored for longer periods. These findings can help diversify scion/rootstock cultivars to produce pasteurized orange juice with higher nutritional value.

HORTICULTURAE (2023)

Article Horticulture

Non-Thermal Plasma and Soilless Nutrient Solution Application: Effects on Nutrient Film Technique Lettuce Cultivation

Carlo Nicoletto, Valentina Falcioni, Silvia Locatelli, Paolo Sambo

Summary: Soilless cultivation is a sustainable intensification practice with high resource use efficiency. Cold plasma applied to the nutrient solution in agriculture can increase safety and reduce chemical use. This study found that cold plasma positively affected nutrient depletion, yield, and quality traits of lettuce.

HORTICULTURAE (2023)

Article Biochemistry & Molecular Biology

Integration of DNA-RNA-triplex-based regulation of transcription into molecular logic gates

Graziano Rilievo, Alessandro Cecconello, Nima Fouladi Ghareshiran, Massimiliano Magro, Friedrich C. Simmel, Fabio Vianello

Summary: In recent years, noncoding RNA molecules have been discovered to play a potential role in gene regulation as components of endogenous DNA-RNA hybrid triplexes. These triplexes, which are involved in complex molecular signaling networks, hold the key to engineering biological computing components. In this study, researchers successfully constructed triplex-based molecular gates, including XOR, XNOR, and a threshold gate, through the transcription of a fluorogenic RNA aptamer. These biomolecular-integrated systems demonstrated precise modulation over a wide range of transcriptional outputs, showcasing the potential for developing molecular gates using DNA-RNA triplex nanostructures.

FEBS LETTERS (2023)

Article Plant Sciences

Maternal-fetal toxicity of Strychnos pseudoquina extract treatment during pregnancy

Maysa Rocha Souza, Evelyn Caroline Barbosa Brito, Linne Stephane Furtado, Vinicius Soares Barco, Larissa Lopes da Cruz, Rafaianne Queiroz Moraes-Souza, Gean Charles Monteiro, Giuseppina Pace Pereira Lima, Debora Cristina Damasceno, Gustavo Tadeu Volpato

Summary: This study evaluated the effect of Strychnos pseudoquina aqueous extract on maternal reproductive toxicity and fetal development. The results showed that the treatment caused elevated liver enzymatic activities, exhibited abortifacient activity at high dosage, and contributed to maternal toxicity and impaired embryofetal development. Therefore, the use of this plant should be completely avoided during pregnancy to prevent unintended abortion and risks to maternal-fetal health.

JOURNAL OF ETHNOPHARMACOLOGY (2023)

Article Agriculture, Multidisciplinary

Training systems improved agronomic characteristics and quality of 'Niagara Rosada' table grapes

Adilson Pimentel, Francisco Jose Domingues Neto, Leticia Silva Pereira Basilio, Gean Charles Monteiro, Giuseppina Pace Pereira Lima, Marco Antonio Tecchio

Summary: Three training systems (conventional, high, and double training) were studied for 'Niagara Rosada vine, and they had different effects on the yield, physicochemical, and antioxidant characteristics of the grapes. The training systems did not influence the fruit production per vine and yield, but they did affect the number of berries per bunch and the fresh mass of berries. Grapes from the double training system had higher soluble solids contents, while the high training system provided grapes with a greater content of bioactive compounds and antioxidant activity.

BRAGANTIA (2023)

Article Business

Urban environmental quality: a study on the economic valuation of urban green areas in Parque do Povo, Presidente Prudente-SP

Claudio Alves Siqueira, Maira Rodrigues Uliana, Alba Regina Azevedo Arana

Summary: This research aimed to quantitatively assess the indirect benefits of Parque do Povo in Presidente Prudente, Brazil, using the Contingent Valuation Method. The study found that 51% of park users are willing to pay for park maintenance and conservation. The park attracts highly educated individuals and is considered an important investment by all respondents. Although the Contingent Valuation Method underestimates the total value, it is effective for determining the monetary value of environmental benefits in urban areas.

REUNIR-REVISTA DE ADMINISTRACAO CONTABILIDADE E SUSTENTABILIDADE (2023)

Article Agriculture, Multidisciplinary

Metabolite profiling reveals the influence of grapevine genetic distance on the chemical signature of juices

Hector Alonzo Gomez Gomez, Guilherme Francio Niederauer, Igor Otavio Minatel, Elisa Ribeiro Miranda Antunes, Mara Junqueira Carneiro, Alexandra Christine Helena Frankland Sawaya, Mauro Celso Zanus, Patricia Silva Ritschel, Vera Quecini, Giuseppina Pace Pereira Lima, Marcia Ortiz Mayo Marques

Summary: The genetic diversity among grapevine cultivars is low, and breeding for agronomic traits increases the contents of soluble sugars, total phenolics, and anthocyanins in grape juices. The metabolic profiles of the juices accurately reflect the genetic distances between cultivars.

JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE (2023)

Article Reproductive Biology

Toxicological effects of the Curatella americana extract in embryo development of female pups from diabetic rats

Larissa Lopes Cruz, Vinicius Soares Barco, Veronyca Goncalves Paula, Maysa Rocha Souza, Franciane Quintanilha Gallego, Gean Charles Monteiro, Giuseppina Pace Pereira Lima, Debora Cristina Damasceno, Gustavo Tadeu Volpato

Summary: Maternal diabetes can affect the development of offspring, both during fetal life and after birth. This study examines the effects of a plant extract, Curatella americana, on the estrous cycle and preimplantation embryos in adult female pups from diabetic rats. The results show that female pups from diabetic mothers exhibited glucose intolerance, irregular estrous cycles, and a higher percentage of embryos in delayed development. Treatment with the plant extract also disrupted the normal estrous cycle and increased levels of certain compounds that could affect embryonic development and implantation. These findings highlight the importance of avoiding indiscriminate use of medicinal plants, especially during pregnancy.

REPRODUCTIVE BIOLOGY (2023)

Meeting Abstract Cardiac & Cardiovascular Systems

CITRUS BERGAMIA (ENDOBERG®) ATTENUATES SYSTOLIC BLOOD PRESSURE AND PREVENTS CARDIAC OXIDATIVE STRESS, CARDIAC REMODELING AND DYSFUNCTION IN OBESE RATS

M. Belin, T. A. Vieira, N. A. Grandini, J. S. Siqueira, T. L. N. Palacio, E. T. N. Maia, F. V. Francisqueti-Ferron, A. J. T. Ferron, S. G. Z. Bazan, D. H. S. Campos, I. O. Minatel, G. P. P. Lima, G. Lombardo, G. Aldini, C. R. Correa

ATHEROSCLEROSIS (2023)

Article Neurosciences

Tryptophan and Biogenic Amines in the Differentiation and Quality of Honey

Cristine Vanz Borges, Aline Nunes, Vladimir Eliodoro Costa, Ricardo de Oliveira Orsi, Leticia Silva Pereira Basilio, Gean Charles Monteiro, Marcelo Maraschin, Giuseppina Pace Pereira Lima

Summary: Honey is a natural product with varying amino acid and biogenic amine profiles depending on its origin and climate conditions, which can serve as indicators of its geographical source.

INTERNATIONAL JOURNAL OF TRYPTOPHAN RESEARCH (2022)

No Data Available