Leucine restores murine hepatic triglyceride accumulation induced by a low-protein diet by suppressing autophagy and excessive endoplasmic reticulum stress

Fructose supplementation impairs rat liver autophagy through mTORC activation without inducing endoplasmic reticulum stress

(2015) Miguel Baena et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Role of endoplasmic reticulum stress and autophagy as interlinking pathways in the pathogenesis of inflammatory bowel disease

(2015) Shuhei Hosomi et al.   CURRENT OPINION IN GASTROENTEROLOGY

Endoplasmic Reticulum Stress in the Diabetic Kidney, the Good, the Bad and the Ugly

(2015) Robyn Cunard   Journal of Clinical Medicine

Insulin injection restored increased insulin receptor substrate (IRS)-2 protein during short-term protein restriction but did not affect reduced insulin-like growth factor (IGF)-I mRNA or increased triglyceride accumulation in the liver of rats

(2014) Yori Ozaki et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

The FXR agonist 6ECDCA reduces hepatic steatosis and oxidative stress induced by ethanol and low-protein diet in mice

(2014) F.A.R. Lívero et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Hepatoprotective and antioxidant activities of extracts from Salvia—Nelumbinis naturalis against nonalcoholic steatohepatitis induced by methionine- and choline-deficient diet in mice

(2014) Yang Liu et al.   Journal of Translational Medicine

The Endoplasmic Reticulum Stress Sensor IRE1  Protects Cells from Apoptosis Induced by the Coronavirus Infectious Bronchitis Virus

(2014) T. S. Fung et al.   JOURNAL OF VIROLOGY

A single daily meal at the beginning of the active or inactive period inhibits food deprivation–induced fatty liver in mice

(2014) Natsumi Aoki et al.   NUTRITION RESEARCH

Role of Hypoxia Inducing Factor-1β in Alcohol-Induced Autophagy, Steatosis and Liver Injury in Mice

(2014) Hong-Min Ni et al.   PLoS One

Acetylcholinesterase (AChE) inhibition aggravates fasting-induced triglyceride accumulation in the mouse liver

(2014) Shin-Ichi Yokota et al.   FEBS Open Bio

Prevention and reversal of hepatic steatosis with a high-protein diet in mice

(2013) Sonia C. Garcia-Caraballo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Distinct effects of leucine or a mixture of the branched-chain amino acids (leucine, isoleucine, and valine) supplementation on resistance to fatigue, and muscle and liver-glycogen degradation, in trained rats

(2013) Patricia L. Campos-Ferraz et al.   NUTRITION

Leucine and mTORC1: a complex relationship

(2012) Kayleigh M. Dodd et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Hepatic steatosis inhibits autophagic proteolysis via impairment of autophagosomal acidification and cathepsin expression

(2011) Yoshihiro Inami et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A quantitative method for detection of spliced X-box binding protein-1 (XBP1) mRNA as a measure of endoplasmic reticulum (ER) stress

(2011) Annemarie van Schadewijk et al.   CELL STRESS & CHAPERONES

Branched-chain amino acids as pharmacological nutrients in chronic liver disease

(2011) Takumi Kawaguchi et al.   HEPATOLOGY

Genetic determinants of hepatic steatosis in man

(2011) Amanda J. Hooper et al.   JOURNAL OF LIPID RESEARCH

p62 Is a Key Regulator of Nutrient Sensing in the mTORC1 Pathway

(2011) Angeles Duran et al.   MOLECULAR CELL

Defective Hepatic Autophagy in Obesity Promotes ER Stress and Causes Insulin Resistance

(2010) Ling Yang et al.   Cell Metabolism

Potential role of branched-chain amino acids in glucose metabolism through the accelerated induction of the glucose-sensing apparatus in the liver

(2010) Nobito Higuchi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Autophagy in liver diseases

(2010) Pierre-Emmanuel Rautou et al.   JOURNAL OF HEPATOLOGY

Dietary protein deprivation upregulates insulin signaling and inhibits gluconeogenesis in rat liver

(2010) Yuka Toyoshima et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Leucine Deprivation Decreases Fat Mass by Stimulation of Lipolysis in White Adipose Tissue and Upregulation of Uncoupling Protein 1 (UCP1) in Brown Adipose Tissue

(2009) Y. Cheng et al.   DIABETES

Hepatic steatosis, carotid atherosclerosis and metabolic syndrome: the STEATO Study

(2009) Claudio Carallo et al.   JOURNAL OF GASTROENTEROLOGY

Mediobasal Hypothalamic Leucine Sensing Regulates Food Intake through Activation of a Hypothalamus-Brainstem Circuit

(2009) C. Blouet et al.   JOURNAL OF NEUROSCIENCE

Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

(2009) Nao Hosokawa et al.   MOLECULAR BIOLOGY OF THE CELL

Autophagy regulates lipid metabolism

(2009) Rajat Singh et al.   NATURE

Inhibition of apolipoprotein B100 secretion by lipid-induced hepatic endoplasmic reticulum stress in rodents

(2008) Tsuguhito Ota et al.   JOURNAL OF CLINICAL INVESTIGATION