Licochalcone A induces apoptosis through endoplasmic reticulum stress via a phospholipase Cγ1-, Ca2+-, and reactive oxygen species-dependent pathway in HepG2 human hepatocellular carcinoma cells

New directions in ER stress-induced cell death

(2013) Susan E. Logue et al.   APOPTOSIS

Dietary Compound Isoliquiritigenin Inhibits Breast Cancer Neoangiogenesis via VEGF/VEGFR-2 Signaling Pathway

(2013) Zhiyu Wang et al.   PLoS One

Involvement of Endoplasmic Reticulum Stress in Isoliquiritigenin-Induced SKOV-3 Cell Apoptosis

(2013) Xuan Yuan et al.   Recent Patents on Anti-Cancer Drug Discovery

Apicidin induces endoplasmic reticulum stress- and mitochondrial dysfunction-associated apoptosis via phospholipase Cγ1- and Ca2+-dependent pathway in mouse Neuro-2a neuroblastoma cells

(2012) Ji Hyun Choi et al.   APOPTOSIS

Pharmacological targeting of endoplasmic reticulum stress signaling in cancer

(2012) Axel H. Schönthal   BIOCHEMICAL PHARMACOLOGY

VEGF Inhibits Tumor Cell Invasion and Mesenchymal Transition through a MET/VEGFR2 Complex

(2012) Kan V. Lu et al.   CANCER CELL

Molecular mechanisms of sorafenib action in liver cancer cells

(2012) Melchiorre Cervello et al.   CELL CYCLE

Guanylate cyclase activator YC-1 potentiates apoptotic effect of licochalcone A on human epithelial ovarian carcinoma cells via activation of death receptor and mitochondrial pathways

(2012) Chung Soo Lee et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The Chalcone Flavokawain B Induces G2/M Cell-Cycle Arrest and Apoptosis in Human Oral Carcinoma HSC-3 Cells through the Intracellular ROS Generation and Downregulation of the Akt/p38 MAPK Signaling Pathway

(2012) You-Cheng Hseu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Licochalcone A inhibits growth of gastric cancer cells by arresting cell cycle progression and inducing apoptosis

(2011) Xiu-ying Xiao et al.   CANCER LETTERS

Targeting c-Met as a promising strategy for the treatment of hepatocellular carcinoma

(2011) Jianjun Gao et al.   PHARMACOLOGICAL RESEARCH

Linking endoplasmic reticulum stress to cell death in hepatocytes: roles of C/EBP homologous protein and chemical chaperones in palmitate-mediated cell death

(2010) Kyle T. Pfaffenbach et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Antiangiogenic effect of licochalcone A

(2010) Yoon Hee Kim et al.   BIOCHEMICAL PHARMACOLOGY

Molecularly targeted therapy in hepatocellular carcinoma

(2010) Hung Huynh   BIOCHEMICAL PHARMACOLOGY

Antitumor and antimetastatic effects of licochalcone A in mouse models

(2010) Jin-Kyung Kim et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Vascular endothelial growth factor regulates myeloid cell leukemia-1 expression through neuropilin-1-dependent activation of c-MET signaling in human prostate cancer cells

(2010) Shumin Zhang et al.   Molecular Cancer

Molecular Classification and Novel Targets in Hepatocellular Carcinoma: Recent Advancements

(2010) Yujin Hoshida et al.   SEMINARS IN LIVER DISEASE

Mechanisms and Implications of Reactive Oxygen Species Generation During the Unfolded Protein Response: Roles of Endoplasmic Reticulum Oxidoreductases, Mitochondrial Electron Transport, and NADPH Oxidase

(2009) Célio X.C. Santos et al.   ANTIOXIDANTS & REDOX SIGNALING

Licochalcone A significantly suppresses LPS signaling pathway through the inhibition of NF-κB p65 phosphorylation at serine 276

(2009) Jun-ichi Furusawa et al.   CELLULAR SIGNALLING

Sunitinib in solid tumors

(2009) Hui K Gan et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Licorice and Licochalcone-A Induce Autophagy in LNCaP Prostate Cancer Cells by Suppression of Bcl-2 Expression and the mTOR Pathway

(2009) Yi-Te Yo et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Targeted therapy for hepatocellular carcinoma

(2009) Hans Christian Spangenberg et al.   Nature Reviews Gastroenterology & Hepatology

VEGF Stimulates the ERK 1/2 Signaling Pathway and Apoptosis in Cerebral Endothelial Cells After Ischemic Conditions

(2009) Purnima Narasimhan et al.   STROKE

Licochalcone A Inhibits the Growth of Colon Carcinoma and Attenuates Cisplatin-Induced Toxicity without a Loss of Chemotherapeutic Efficacy in Mice

(2008) Chang Ki Lee et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Regulation of the Met Receptor-tyrosine Kinase by the Protein-tyrosine Phosphatase 1B and T-cell Phosphatase

(2008) Veena Sangwan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Overexpressed cyclophilin B suppresses apoptosis associated with ROS and Ca2+ homeostasis after ER stress

(2008) J. Kim et al.   JOURNAL OF CELL SCIENCE

Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

(2008) Inki Kim et al.   NATURE REVIEWS DRUG DISCOVERY