Dietary Compound Isoliquiritigenin Inhibits Breast Cancer Neoangiogenesis via VEGF/VEGFR-2 Signaling Pathway

Angiogenesis as a therapeutic target in cancer

(2013) G. Kumaran et al.   CLINICAL MEDICINE

Ellagic acid, a phenolic compound, exerts anti-angiogenesis effects via VEGFR-2 signaling pathway in breast cancer

(2012) Neng Wang et al.   BREAST CANCER RESEARCH AND TREATMENT

Emerging Glycolysis Targeting and Drug Discovery from Chinese Medicine in Cancer Therapy

(2012) Zhiyu Wang et al.   Evidence-based Complementary and Alternative Medicine

Isoliquiritigenin from licorice root suppressed neovascularisation in experimental ocular angiogenesis models

(2011) V. Jhanji et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Design, synthesis, and evaluation of 5-methyl-4-phenoxy-5H-pyrrolo[3,2-d]pyrimidine derivatives: Novel VEGFR2 kinase inhibitors binding to inactive kinase conformation

(2010) Yuya Oguro et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Cancer Chemopreventive Activity and Metabolism of Isoliquiritigenin, a Compound Found in Licorice

(2010) M. Cuendet et al.   Cancer Prevention Research

Differential Effects of VEGFR-1 and VEGFR-2 Inhibition on Tumor Metastases Based on Host Organ Environment

(2010) Y.-J. Lee et al.   CANCER RESEARCH

VEGFR-3 ligand-binding and kinase activity are required for lymphangiogenesis but not for angiogenesis

(2010) Luqing Zhang et al.   CELL RESEARCH

Bevacizumab toxicities and their management in ovarian cancer

(2010) Leslie M. Randall et al.   GYNECOLOGIC ONCOLOGY

Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs): Positive and negative regulators in tumor cell adhesion

(2010) Dimitra Bourboulia et al.   SEMINARS IN CANCER BIOLOGY

Tissue factor in cancer progression and angiogenesis

(2010) Wolfram Ruf et al.   THROMBOSIS RESEARCH

Use of anti-VEGF adjuvant therapy in cancer: challenges and rationale

(2010) Anil Bagri et al.   TRENDS IN MOLECULAR MEDICINE

VEGF receptor trafficking in angiogenesis: Figure 1

(2009) Alice Scott et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Isoliquiritigenin induces G2 and M phase arrest by inducing DNA damage and by inhibiting the metaphase/anaphase transition

(2009) Iha Park et al.   CANCER LETTERS

Induction of Cell Cycle Arrest in Prostate Cancer Cells by the Dietary Compound Isoliquiritigenin

(2009) Yeo Myeong Lee et al.   JOURNAL OF MEDICINAL FOOD

Licorice isoliquiritigenin dampens angiogenic activity via inhibition of MAPK-responsive signaling pathways leading to induction of matrix metalloproteinases

(2009) Sang-Wook Kang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Targeting angiogenesis: progress with anti-VEGF treatment with large molecules

(2009) Axel Grothey et al.   Nature Reviews Clinical Oncology

AKT Signaling in Regulating Angiogenesis

(2008) Bing-Hua Jiang et al.   CURRENT CANCER DRUG TARGETS

Isoliquiritigenin induces monocytic differentiation of HL-60 cells

(2008) Defang Li et al.   FREE RADICAL BIOLOGY AND MEDICINE

Dietary administration of the licorice flavonoid isoliquiritigenin deters the growth of MCF-7 cells overexpressing aromatase

(2008) Lan Ye et al.   INTERNATIONAL JOURNAL OF CANCER

Adenovirus-mediated transfer of siRNA against MMP-2 mRNA results in impaired invasion and tumor-induced angiogenesis, induces apoptosis in vitro and inhibits tumor growth in vivo in glioblastoma

(2008) O Kargiotis et al.   ONCOGENE