Redox Metabolism in Mitochondria of Trypanosomatids

Tryparedoxin peroxidases and superoxide dismutases expression as well as ROS release are related to Trypanosoma cruzi epimastigotes growth phases

(2012) Eduardo F. Peloso et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Leishmania major Peroxidase Is a Cytochrome c Peroxidase

(2012) Victoria S. Jasion et al.   BIOCHEMISTRY

Leishmania donovani mitochondrial iron superoxide dismutase A is released into the cytosol during miltefosine induced programmed cell death

(2012) Fitsum Getachew et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Basic Principles and Emerging Concepts in the Redox Control of Transcription Factors

(2011) Regina Brigelius-Flohé et al.   ANTIOXIDANTS & REDOX SIGNALING

Peroxiredoxins in Parasites

(2011) Michael C. Gretes et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial Preprotein Translocase of Trypanosomatids Has a Bacterial Origin

(2011) Mascha Pusnik et al.   CURRENT BIOLOGY

A tryparedoxin-dependent peroxidase protects African trypanosomes from membrane damage

(2011) Michael Diechtierow et al.   FREE RADICAL BIOLOGY AND MEDICINE

Multiple roles of proline transport and metabolism in trypanosomatids

(2011) Frederic Bringaud   Frontiers in Bioscience-Landmark

O2 consumption rates along the growth curve: new insights into Trypanosoma cruzi mitochondrial respiratory chain

(2011) Thiago M. Silva et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

A comparative assessment of mitochondrial function in epimastigotes and bloodstream trypomastigotes of Trypanosoma cruzi

(2011) Renata L. S. Gonçalves et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Trypanosoma bruceiMitochondrial Respiratome: Composition and Organization in Procyclic Form

(2011) Nathalie Acestor et al.   MOLECULAR & CELLULAR PROTEOMICS

Mitochondrial dysfunction in Trypanosoma cruzi: the role of Serratia marcescens prodigiosin in the alternative treatment of Chagas disease

(2011) Carlos Genes et al.   Parasites & Vectors

Leishmania Mitochondrial Peroxiredoxin Plays a Crucial Peroxidase-Unrelated Role during Infection: Insight into Its Novel Chaperone Activity

(2011) Helena Castro et al.   PLoS Pathogens

Tafenoquine, an Antiplasmodial 8-Aminoquinoline, Targets Leishmania Respiratory Complex III and Induces Apoptosis

(2010) L. Carvalho et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Tryparedoxin peroxidases from Trypanosoma cruzi: High efficiency in the catalytic elimination of hydrogen peroxide and peroxynitrite

(2010) María Dolores Piñeyro et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Cysteine residues exposed on protein surfaces are the dominant intramitochondrial thiol and may protect against oxidative damage

(2010) Raquel Requejo et al.   FEBS Journal

The Dithiol Glutaredoxins of African Trypanosomes Have Distinct Roles and Are Closely Linked to the Unique Trypanothione Metabolism

(2010) Sevgi Ceylan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Complex I (NADH:ubiquinone oxidoreductase) is active in but non-essential for procyclic Trypanosoma brucei

(2010) Zdeněk Verner et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Ascorbate Peroxidase from Leishmania major Controls the Virulence of Infective Stage of Promastigotes by Regulating Oxidative Stress

(2010) Swati Pal et al.   PLoS One

Mitochondrial Redox Metabolism in Trypanosomatids Is Independent of Tryparedoxin Activity

(2010) Helena Castro et al.   PLoS One

Cloning, Expression, and Characterization of a Dithiol Glutaredoxin from Trypanosoma cruzi

(2009) Vanina E. Marquez et al.   ANTIOXIDANTS & REDOX SIGNALING

Overexpression of MitochondrialLeishmania majorAscorbate Peroxidase Enhances Tolerance to Oxidative Stress-Induced Programmed Cell Death and Protein Damage

(2009) Subhankar Dolai et al.   EUKARYOTIC CELL

Mitochondria and reactive oxygen species

(2009) Alicia J. Kowaltowski et al.   FREE RADICAL BIOLOGY AND MEDICINE

Enzymes of the antioxidant network as novel determiners of Trypanosoma cruzi virulence

(2009) L. Piacenza et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Particularities of mitochondrial structure in parasitic protists (Apicomplexa and Kinetoplastida)

(2009) Wanderley de Souza et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Mitochondrial bioenergetics and redox state are unaltered in Trypanosoma cruzi isolates with compromised mitochondrial complex I subunit genes

(2009) Julio César Carranza et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Phylogenomic analyses support the monophyly of Excavata and resolve relationships among eukaryotic "supergroups"

(2009) V. Hampl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Surprising variety in energy metabolism within Trypanosomatidae

(2009) Aloysius G.M. Tielens et al.   TRENDS IN PARASITOLOGY

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Leishmania infantum: Provision of reducing equivalents to the mitochondrial tryparedoxin/tryparedoxin peroxidase system

(2008) Helena Castro et al.   EXPERIMENTAL PARASITOLOGY

Order within a mosaic distribution of mitochondrial c-type cytochrome biogenesis systems?

(2008) James W. A. Allen et al.   FEBS Journal

Leishmania major ascorbate peroxidase overexpression protects cells against reactive oxygen species-mediated cardiolipin oxidation

(2008) Subhankar Dolai et al.   FREE RADICAL BIOLOGY AND MEDICINE

Were class C iron-containing superoxide dismutases of trypanosomatid parasites initially imported into a complex plastid? A hypothesis based on analyses of their N-terminal targeting signals

(2008) A. BODYŁ et al.   PARASITOLOGY

Complex I of Trypanosomatidae: does it exist?

(2008) Fred R. Opperdoes et al.   TRENDS IN PARASITOLOGY

Cloning, functional analysis, and mitochondrial localization of Trypanosoma brucei monothiol glutaredoxin-1

(2007) Michael Filser et al.   BIOLOGICAL CHEMISTRY

Peroxiredoxins from Trypanosoma cruzi: Virulence factors and drug targets for treatment of Chagas disease?

(2007) María Dolores Piñeyro et al.   GENE