Statins in traumatic brain injury

Statin Therapy Inhibits Remyelination in the Central Nervous System

(2009) Veronique E. Miron et al.   AMERICAN JOURNAL OF PATHOLOGY

Atorvastatin ameliorates cerebral vasospasm and early brain injury after subarachnoid hemorrhage and inhibits caspase-dependent apoptosis pathway

(2009) Gao Cheng et al.   BMC NEUROSCIENCE

Simvastatin reduces secondary brain injury caused by cortical contusion in rats: Possible involvement of TLR4/NF-κB pathway

(2009) Gang Chen et al.   EXPERIMENTAL NEUROLOGY

Biologic Effects of Simvastatin in Patients with Aneurysmal Subarachnoid Hemorrhage: A Double-Blind, Placebo-Controlled Randomized Trial

(2009) Mervyn DI Vergouwen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Statins may not protect against vasospasm in subarachnoid haemorrhage

(2009) Michael Kern et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Simvastatin for the prevention of symptomatic cerebral vasospasm following aneurysmal subarachnoid hemorrhage: a single-institution prospective cohort study

(2009) Matthew J. McGirt et al.   JOURNAL OF NEUROSURGERY

Combination Therapies for Traumatic Brain Injury: Prospective Considerations

(2009) Susan Margulies et al.   JOURNAL OF NEUROTRAUMA

Reduction in C-reactive protein and LDL cholesterol and cardiovascular event rates after initiation of rosuvastatin: a prospective study of the JUPITER trial

(2009) Paul M Ridker et al.   LANCET

Prior Use of Statins Improves Outcome in Patients With Intracerebral Hemorrhage

(2009) Ronen R. Leker et al.   STROKE

Unique challenges in clinical trials in traumatic brain injury

(2008) David K. Menon   CRITICAL CARE MEDICINE

The Neuroprotection with Statin Therapy for Acute Recovery Trial (Neustart): An Adaptive Design Phase I Dose-Escalation Study of High-Dose Lovastatin in Acute Ischemic Stroke

(2008) Mitchell S. V. Elkind et al.   International Journal of Stroke

Acute Treatment with Rosuvastatin Protects Insulin Resistant (C57BL/6J ob/ob) Mice against Transient Cerebral Ischemia

(2008) Keita Mayanagi et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Simvastatin attenuation of cerebral vasospasm after subarachnoid hemorrhage in rats via increased phosphorylation of Akt and endothelial nitric oxide synthase

(2008) Takashi Sugawara et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Increase in phosphorylation of Akt and its downstream signaling targets and suppression of apoptosis by simvastatin after traumatic brain injury

(2008) Hongtao Wu et al.   JOURNAL OF NEUROSURGERY

Effect of Rosuvastatin on Amnesia and Disorientation after Traumatic Brain Injury (NCT00329758)

(2008) J. Humberto Tapia-Perez et al.   JOURNAL OF NEUROTRAUMA

Simvastatin-Mediated Upregulation of VEGF and BDNF, Activation of the PI3K/Akt Pathway, and Increase of Neurogenesis Are Associated with Therapeutic Improvement after Traumatic Brain Injury

(2008) Hongtao Wu et al.   JOURNAL OF NEUROTRAUMA

Long-Lasting Benefits after Treatment of Traumatic Brain Injury (TBI) in Rats with Combination Therapy of Marrow Stromal Cells (MSCs) and Simvastatin

(2008) Asim Mahmood et al.   JOURNAL OF NEUROTRAUMA

Combination Therapy with Fenofibrate, a Peroxisome Proliferator-Activated Receptor   Agonist, and Simvastatin, a 3-Hydroxy-3-methylglutaryl-Coenzyme A Reductase Inhibitor, on Experimental Traumatic Brain Injury

(2008) X. R. Chen et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

A case control study of statin and magnesium administration in patients after aneurysmal subarachnoid hemorrhage: incidence of delayed cerebral ischemia and mortality

(2008) Thomas Kerz et al.   NEUROLOGICAL RESEARCH

STATIN USE WAS NOT ASSOCIATED WITH LESS VASOSPASM OR IMPROVED OUTCOME AFTER SUBARACHNOID HEMORRHAGE

(2008) Andreas H. Kramer et al.   NEUROSURGERY

Multifunctional drugs for head injury

(2008) Robert Vink et al.   Neurotherapeutics

Effect of Statins on Intracerebral Hemorrhage Outcome and Recurrence

(2008) Emilie FitzMaurice et al.   STROKE

A Randomized, Double-Blind, Placebo-Controlled Pilot Study of Simvastatin in Aneurysmal Subarachnoid Hemorrhage

(2008) Sherry H.-Y. Chou et al.   STROKE

Simvastatin Reduces the Association of NMDA Receptors to Lipid Rafts

(2008) Jovita Ponce et al.   STROKE

Atorvastatin efficiency after traumatic brain injury in rats

(2008) Omer Faruk Turkoglu et al.   SURGICAL NEUROLOGY

Intravenous Rosuvastatin for Acute Stroke Treatment

(2007) Vincent Prinz et al.   STROKE