Playing with Cardiac “Redox Switches”: The “HNO Way” to Modulate Cardiac Function

Nitroxyl (HNO) as a Vasoprotective Signaling Molecule

(2010) Michelle L. Bullen et al.   ANTIOXIDANTS & REDOX SIGNALING

Nitric Oxide/Reactive Oxygen Species Generation and Nitroso/Redox Imbalance in Heart Failure: From Molecular Mechanisms to Therapeutic Implications

(2010) Chiara Nediani et al.   ANTIOXIDANTS & REDOX SIGNALING

The new HNO donor, 1-nitrosocyclohexyl acetate, increases contractile force in normal and β-adrenergically desensitized ventricular myocytes

(2010) Ali El-Armouche et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hydrogen sulfide interacts with nitric oxide in the heart: possible involvement of nitroxyl

(2010) Q.-C. Yong et al.   CARDIOVASCULAR RESEARCH

Role of Inotropic Agents in the Treatment of Heart Failure

(2010) Joshua I. Goldhaber et al.   CIRCULATION

Reactions of HNO with Heme Proteins: New Routes to HNO−Heme Complexes and Insight into Physiological Effects

(2010) Murugaeson R. Kumar et al.   INORGANIC CHEMISTRY

Isopropylamine NONOate (IPA/NO) moderates neointimal hyperplasia following vascular injury

(2010) Nick D. Tsihlis et al.   JOURNAL OF VASCULAR SURGERY

Adrenergic Signaling Polymorphisms and Their Impact on Cardiovascular Disease

(2010) Gerald W. Dorn   PHYSIOLOGICAL REVIEWS

JAK redux: a second look at the regulation and role of JAKs in the heart

(2009) Mazen Kurdi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Disulfides as Redox Switches: From Molecular Mechanisms to Functional Significance

(2009) Merridee A. Wouters et al.   ANTIOXIDANTS & REDOX SIGNALING

A role for nitroxyl (HNO) as an endothelium-derived relaxing and hyperpolarizing factor in resistance arteries

(2009) Karen L Andrews et al.   BRITISH JOURNAL OF PHARMACOLOGY

Nitroxyl Activates SERCA in Cardiac Myocytes via Glutathiolation of Cysteine 674

(2009) Steve Lancel et al.   CIRCULATION RESEARCH

Protein Cysteine Modifications: (2) Reactivity Specificity and Topics of Medicinal Chemistry and Protein Engineering

(2009) N. Nagahara et al.   CURRENT MEDICINAL CHEMISTRY

Inotropic therapy for heart failure: paradise lost

(2009) J. N. Cohn   EUROPEAN HEART JOURNAL

The L-type Ca2+ Channel as a Potential Mediator of Pathology During Alterations in Cellular Redox State

(2009) Livia C. Hool   Heart Lung and Circulation

Nitroxyl exacerbates ischemic cerebral injury and oxidative neurotoxicity

(2009) Chi-un Choe et al.   JOURNAL OF NEUROCHEMISTRY

Identification of Nitroxyl-induced Modifications in Human Platelet Proteins Using a Novel Mass Spectrometric Detection Method

(2009) Michael D. Hoffman et al.   MOLECULAR & CELLULAR PROTEOMICS

Xerogel Optical Sensor Films for Quantitative Detection of Nitroxyl

(2008) Kevin P. Dobmeier et al.   ANALYTICAL CHEMISTRY

Oxidation of Myofilament Protein Sulfhydryl Groups Reduces the Contractile Force and Its Ca2+ Sensitivity in Human Cardiomyocytes

(2008) Zita Hertelendi et al.   ANTIOXIDANTS & REDOX SIGNALING

Thiol Chemistry in Peroxidase Catalysis and Redox Signaling

(2008) Alberto Bindoli et al.   ANTIOXIDANTS & REDOX SIGNALING

Phospholamban Thiols Play a Central Role in Activation of the Cardiac Muscle Sarcoplasmic Reticulum Calcium Pump by Nitroxyl†

(2008) Jeffrey P. Froehlich et al.   BIOCHEMISTRY

Redox Modification of Ryanodine Receptors Contributes to Sarcoplasmic Reticulum Ca 2+ Leak in Chronic Heart Failure

(2008) Dmitry Terentyev et al.   CIRCULATION RESEARCH

Generation of nitroxyl by heme protein-mediated peroxidation of hydroxylamine but not N-hydroxy-L-arginine

(2008) Sonia Donzelli et al.   FREE RADICAL BIOLOGY AND MEDICINE