Nitric Oxide/Reactive Oxygen Species Generation and Nitroso/Redox Imbalance in Heart Failure: From Molecular Mechanisms to Therapeutic Implications

Mitochondrial KATP channels-derived reactive oxygen species activate pro-survival pathway in pravastatin-induced cardioprotection

(2010) Luong Cong Thuc et al.   APOPTOSIS

Glucagon-Like Peptide 1 Prevents Reactive Oxygen Species–Induced Endothelial Cell Senescence Through the Activation of Protein Kinase A

(2010) Hisko Oeseburg et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Redox signaling (cross-talk) from and to mitochondria involves mitochondrial pores and reactive oxygen species

(2010) Andreas Daiber   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The Cardiovascular Nutrapharmacology of Resveratrol: Pharmacokinetics, Molecular Mechanisms and Therapeutic Potential

(2010) Paul A. Kroon et al.   CURRENT MEDICINAL CHEMISTRY

SIRT1 mRNA Expression May Be Associated With Energy Expenditure and Insulin Sensitivity

(2010) J. Rutanen et al.   DIABETES

Switching to Once-Daily Liraglutide From Twice-Daily Exenatide Further Improves Glycemic Control in Patients With Type 2 Diabetes Using Oral Agents

(2010) J. B. Buse et al.   DIABETES CARE

Exenatide is Non-inferior to Insulin in Reducing HbA1c: An Integrated Analysis of 1423 Patients with Type 2 Diabetes

(2010) Thomas Blevins et al.   POSTGRADUATE MEDICINE

Current Status of Stem Cell Therapy in Heart Failure

(2010) Marta Codina et al.   Current Cardiology Reports

Regulation of glucose transporter 4 traffic by energy deprivation from mitochondrial compromise

(2009) A. Klip et al.   Acta Physiologica

Meta-Analysis of Randomized Controlled Trials of Statins Versus Placebo in Patients With Heart Failure

(2009) Michael J. Lipinski et al.   AMERICAN JOURNAL OF CARDIOLOGY

Feed-forward signaling of TNF-α and NF-κB via IKK-β pathway contributes to insulin resistance and coronary arteriolar dysfunction in type 2 diabetic mice

(2009) Jiyeon Yang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Hypersensitivity of excitation-contraction coupling in dystrophic cardiomyocytes

(2009) Nina D. Ullrich et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The Role of Nitric Oxide in Myocardial Repair and Remodeling

(2009) Hajime Otani   ANTIOXIDANTS & REDOX SIGNALING

Angiomyogenesis for Myocardial Repair

(2009) Husnain Kh Haider et al.   ANTIOXIDANTS & REDOX SIGNALING

Redox Regulation of Cell Survival by the Thioredoxin Superfamily: An Implication of Redox Gene Therapy in the Heart

(2009) Md. Kaimul Ahsan et al.   ANTIOXIDANTS & REDOX SIGNALING

Effects of rosuvastatin on myeloperoxidase levels in patients with chronic heart failure: A randomized placebo-controlled study

(2009) Ioannis Andreou et al.   ATHEROSCLEROSIS

The contribution of incretin hormones to the pathogenesis of type 2 diabetes

(2009) Juris J. Meier   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

The role of nitric oxide and reactive oxygen species in the positive inotropic response to mechanical stretch in the mammalian myocardium

(2009) Yin Hua Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Enhanced ROS production by NADPH oxidase is correlated to changes in antioxidant enzyme activity in human heart failure

(2009) Elisabetta Borchi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Emerging concepts in cardiac matrix biologyThis article is one of a selection of papers published in a special issue on Advances in Cardiovascular Research.

(2009) Leon Espira et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Intensive insulin therapy and mortality among critically ill patients: a meta-analysis including NICE-SUGAR study data

(2009) D. E. G. Griesdale et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

Increased Glucose Uptake and Oxidation in Mouse Hearts Prevent High Fatty Acid Oxidation but Cause Cardiac Dysfunction in Diet-Induced Obesity

(2009) Jie Yan et al.   CIRCULATION

Contribution of Impaired Myocardial Insulin Signaling to Mitochondrial Dysfunction and Oxidative Stress in the Heart

(2009) Sihem Boudina et al.   CIRCULATION

Nitric Oxide Increases Cardiac I K1 by Nitrosylation of Cysteine 76 of Kir2.1 Channels

(2009) Ricardo Gómez et al.   CIRCULATION RESEARCH

Cardiac Na + Current Regulation by Pyridine Nucleotides

(2009) Man Liu et al.   CIRCULATION RESEARCH

Monoamine Oxidase A–Mediated Enhanced Catabolism of Norepinephrine Contributes to Adverse Remodeling and Pump Failure in Hearts With Pressure Overload

(2009) Nina Kaludercic et al.   CIRCULATION RESEARCH

Reactive oxygen species and insulin-resistant cardiomyopathy

(2009) Kimberley M Mellor et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

GLP-1R Agonist Liraglutide Activates Cytoprotective Pathways and Improves Outcomes After Experimental Myocardial Infarction in Mice

(2009) M. H. Noyan-Ashraf et al.   DIABETES

One-Year Treatment With Exenatide Improves  -Cell Function, Compared With Insulin Glargine, in Metformin-Treated Type 2 Diabetic Patients: A randomized, controlled trial

(2009) M. C. Bunck et al.   DIABETES CARE

Nebivolol

(2009) Otto Kamp et al.   DRUGS

Effects of rosuvastatin on atrial fibrillation occurrence: ancillary results of the GISSI-HF trial

(2009) A. P. Maggioni et al.   EUROPEAN HEART JOURNAL

Nox proteins in signal transduction

(2009) David I. Brown et al.   FREE RADICAL BIOLOGY AND MEDICINE

Redox sensitive signaling pathways in cardiac remodeling, hypertrophy and failure

(2009) Narayana Anilkumar   Frontiers in Bioscience-Landmark

Mitochondrial nitric oxide synthase: current concepts and controversies

(2009) Zsombor Lacza   Frontiers in Bioscience-Landmark

Evidence for a Causal Role of Oxidative Stress in the Myocardial Complications of Insulin Resistance

(2009) Rebecca H. Ritchie   Heart Lung and Circulation

The L-type Ca2+ Channel as a Potential Mediator of Pathology During Alterations in Cellular Redox State

(2009) Livia C. Hool   Heart Lung and Circulation

Losartan Metabolite EXP3179 Blocks NADPH Oxidase-Mediated Superoxide Production by Inhibiting Protein Kinase C

(2009) Ana Fortuño et al.   HYPERTENSION

Protein Kinase C-Inhibiting Properties of the Losartan Metabolite EXP3179 Make the Difference

(2009) Philip Wenzel et al.   HYPERTENSION

MitoKATP activity in healthy and ischemic hearts

(2009) Alexandre D. T. Costa et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Redox signaling and protein phosphorylation in mitochondria: progress and prospects

(2009) D. Brian Foster et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Palmitate Induces Insulin Resistance in H4IIEC3 Hepatocytes through Reactive Oxygen Species Produced by Mitochondria

(2009) Seiji Nakamura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanosensitive Channels in Striated Muscle and the Cardiovascular System: Not Quite a Stretch Anymore

(2009) Jonathan A Stiber et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Autophagy in transition from hypertrophic cardiomyopathy to heart failure

(2009) A. Fidzianska et al.   Microscopy

NADPH oxidase signaling and cardiac myocyte function

(2009) Ashwin Akki et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Palmitate attenuates myocardial contractility through augmentation of repolarizing Kv currents

(2009) Todd E. Haim et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The inhibition of pyruvate dehydrogenase kinase improves impaired cardiac function and electrical remodeling in two models of right ventricular hypertrophy: resuscitating the hibernating right ventricle

(2009) Lin Piao et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Endogenous Nitric Oxide Contributes to Bradykinin-Stimulated Glucose Uptake but Attenuates Vascular Tissue-Type Plasminogen Activator Release

(2009) M. Pretorius et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The Adrenergic-Fatty Acid Load in Heart Failure

(2009) Lionel H. Opie et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Beta-Blockade With Nebivolol in Elderly Heart Failure Patients With Impaired and Preserved Left Ventricular Ejection Fraction

(2009) Dirk J. van Veldhuisen et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Effects of high-dose versus low-dose losartan on clinical outcomes in patients with heart failure (HEAAL study): a randomised, double-blind trial

(2009) Marvin A Konstam et al.   LANCET

Nitric oxide and nitric oxide synthase isoforms in the normal, hypertrophic, and failing heart

(2009) Soban Umar et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Myocardial remodeling after infarction: the role of myofibroblasts

(2009) Susanne W. M. van den Borne et al.   Nature Reviews Cardiology

Glucagon-like peptide-1 (GLP-1) protects against methylglyoxal-induced PC12 cell apoptosis through the PI3K/Akt/mTOR/GCLc/redox signaling pathway

(2009) R. Kimura et al.   NEUROSCIENCE

Pathophysiology and Clinical Implications of Cardiac Memory

(2009) DARWIN JEYARAJ et al.   PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY

Novel therapeutics for type 2 diabetes: Incretin hormone mimetics (glucagon-like peptide-1 receptor agonists) and dipeptidyl peptidase-4 inhibitors

(2009) E.J. Verspohl   PHARMACOLOGY & THERAPEUTICS

DPP-4 Inhibitors in Clinical Practice

(2009) Anna I. Palalau et al.   POSTGRADUATE MEDICINE

Characterization of Hepatic Mitochondrial Injury Induced by Fatty Acid Oxidation Inhibitors

(2009) Alison E.M. Vickers   TOXICOLOGIC PATHOLOGY

The transcriptional coactivator PGC-1α is essential for maximal and efficient cardiac mitochondrial fatty acid oxidation and lipid homeostasis

(2008) John J. Lehman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Statins in Endothelial Signaling and Activation

(2008) Jeffrey R. Jacobson   ANTIOXIDANTS & REDOX SIGNALING

Crucial role for LKB1 to AMPKα2 axis in the regulation of CD36-mediated long-chain fatty acid uptake into cardiomyocytes☆

(2008) Daphna D.J. Habets et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Loss of PTEN attenuates the development of pathological hypertrophy and heart failure in response to biomechanical stress

(2008) G. Y. Oudit et al.   CARDIOVASCULAR RESEARCH

Potential novel pharmacological therapies for myocardial remodelling

(2008) U. Landmesser et al.   CARDIOVASCULAR RESEARCH

Mitochondrial oxidative stress and dysfunction in myocardial remodelling

(2008) H. Tsutsui et al.   CARDIOVASCULAR RESEARCH

Regulation of sarcolemmal glucose and fatty acid transporters in cardiac disease

(2008) R. W. Schwenk et al.   CARDIOVASCULAR RESEARCH

Metabolic remodelling of the failing heart: beneficial or detrimental?

(2008) M. van Bilsen et al.   CARDIOVASCULAR RESEARCH

Energy metabolism in heart failure and remodelling

(2008) J. S. Ingwall   CARDIOVASCULAR RESEARCH

Insulin signalling in the heart

(2008) L. Bertrand et al.   CARDIOVASCULAR RESEARCH

A Dynamic Pathway for Calcium-Independent Activation of CaMKII by Methionine Oxidation

(2008) Jeffrey R. Erickson et al.   CELL

Cardiac Myocyte–Specific Expression of Inducible Nitric Oxide Synthase Protects Against Ischemia/Reperfusion Injury by Preventing Mitochondrial Permeability Transition

(2008) Matthew B. West et al.   CIRCULATION

Right Ventricular Function in Cardiovascular Disease, Part I

(2008) François Haddad et al.   CIRCULATION

Cardioprotective and Vasodilatory Actions of Glucagon-Like Peptide 1 Receptor Are Mediated Through Both Glucagon-Like Peptide 1 Receptor–Dependent and –Independent Pathways

(2008) Kiwon Ban et al.   CIRCULATION

Redox Modification of Ryanodine Receptors Contributes to Sarcoplasmic Reticulum Ca 2+ Leak in Chronic Heart Failure

(2008) Dmitry Terentyev et al.   CIRCULATION RESEARCH

Activation of AMP-Activated Protein Kinase by Metformin Improves Left Ventricular Function and Survival in Heart Failure

(2008) Susheel Gundewar et al.   CIRCULATION RESEARCH

Reassessing the Cardiovascular Risks and Benefits of Thiazolidinediones

(2008) Andrew Zinn et al.   CLINICAL CARDIOLOGY

Exenatide effects on diabetes, obesity, cardiovascular risk factors and hepatic biomarkers in patients with type 2 diabetes treated for at least 3 years

(2008) David C. Klonoff et al.   CURRENT MEDICAL RESEARCH AND OPINION

Antioxidant supplements to prevent or slow down the progression of AMD: a systematic review and meta-analysis

(2008) J Evans   EYE

Nox5 mediates PDGF-induced proliferation in human aortic smooth muscle cells

(2008) Desmond B. Jay et al.   FREE RADICAL BIOLOGY AND MEDICINE

Distinct roles of Nox1 and Nox4 in basal and angiotensin II-stimulated superoxide and hydrogen peroxide production

(2008) S DIKALOV et al.   FREE RADICAL BIOLOGY AND MEDICINE

Serotonin-mediated protein carbonylation in the right heart

(2008) Lingling Liu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Redox-based regulation of signal transduction: Principles, pitfalls, and promises

(2008) Yvonne M.W. Janssen-Heininger et al.   FREE RADICAL BIOLOGY AND MEDICINE

Bidirectional Actions of Hydrogen Peroxide on Endothelial Nitric-oxide Synthase Phosphorylation and Function

(2008) Zhuangli Hu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glycolytic Oscillations in Isolated Rabbit Ventricular Myocytes

(2008) Jun-Hai Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nitrosative Stress Leads to Protein Glutathiolation, IncreasedS-Nitrosation, and Up-regulation of Peroxiredoxins in the Heart

(2008) Michael Reinartz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ranolazine Inhibits An Oxidative Stress-induced Increase in Myocyte Sodium and Calcium Loading During Simulated-demand Ischemia

(2008) Xiu Q Zhang et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Role of NADPH oxidase in H9c2 cardiac muscle cells exposed to simulated ischaemia-reperfusion

(2008) Elisabetta Borchi et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Tricuspid Annular Motion as a Predictor of Severe Right Ventricular Failure After Left Ventricular Assist Device Implantation

(2008) Sarinya Puwanant et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Increased mitochondrial uncoupling proteins, respiratory uncoupling and decreased efficiency in the chronically infarcted rat heart

(2008) Andrew J. Murray et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Cardioprotective signaling to mitochondria

(2008) Keith D. Garlid et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Time Course of Alterations in Myocardial Glucose Utilization in the Zucker Diabetic Fatty Rat with Correlation to Gene Expression of Glucose Transporters: A Small-Animal PET Investigation

(2008) K. I. Shoghi et al.   JOURNAL OF NUCLEAR MEDICINE

Endothelin-1 Regulates Cardiac L-Type Calcium Channels via NAD(P)H Oxidase-Derived Superoxide

(2008) Q. Zeng et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Hydroxyl radical and glutathione interactions alter calcium sensitivity and maximum force of the contractile apparatus in rat skeletal muscle fibres

(2008) R. M. Murphy et al.   JOURNAL OF PHYSIOLOGY-LONDON

Coenzyme Q10

(2008) Sarah L. Molyneux et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Insulin-Resistant Cardiomyopathy

(2008) Ronald M. Witteles et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Liraglutide versus glimepiride monotherapy for type 2 diabetes (LEAD-3 Mono): a randomised, 52-week, phase III, double-blind, parallel-treatment trial

(2008) Alan Garber et al.   LANCET

The positive inotropic effect of endothelin-1 is mediated by mitochondrial reactive oxygen species

(2008) V.C. De Giusti et al.   LIFE SCIENCES

Nitrite reductase activity of myoglobin regulates respiration and cellular viability in myocardial ischemia-reperfusion injury

(2008) U. B. Hendgen-Cotta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antioxidant treatment for heart failure: friend or foe?

(2008) M. J. Thomson et al.   QJM-AN INTERNATIONAL JOURNAL OF MEDICINE

Mechanisms of Disease: ion channel remodeling in the failing ventricle

(2008) Robert D Nass et al.   Nature clinical practice. Cardiovascular medicine

NF-κB-dependent transcriptional regulation of the cardiac scn5a sodium channel by angiotensin II

(2007) Lijuan L. Shang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Functional coupling of angiotensin II type 1 receptor with insulin resistance of energy substrate uptakes in immortalized cardiomyocytes (HL-1 cells)

(2007) C Alfarano et al.   BRITISH JOURNAL OF PHARMACOLOGY

Thromboxane Receptor Activates the AMP-Activated Protein Kinase in Vascular Smooth Muscle Cells via Hydrogen Peroxide

(2007) Miao Zhang et al.   CIRCULATION RESEARCH

Peptide hormone exendin-4 stimulates subventricular zone neurogenesis in the adult rodent brain and induces recovery in an animal model of parkinson's disease

(2007) Göran Bertilsson et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Late sodium current in failing heart: Friend or foe?

(2007) Victor A. Maltsev et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Protective effects of GLP-1 analogues exendin-4 and GLP-1(9–36) amide against ischemia–reperfusion injury in rat heart

(2007) David P. Sonne et al.   REGULATORY PEPTIDES