Disruption of Hypoxia-Inducible Transcription Factor-Prolyl Hydroxylase Domain-1 (PHD-1−/−) Attenuates Ex Vivo Myocardial Ischemia/Reperfusion Injury Through Hypoxia-Inducible Factor-1α Transcription Factor and Its Target Genes in Mice

Hypoxia inducible factor 1 (HIF-1) and cardioprotection

(2010) Demet Tekin et al.   ACTA PHARMACOLOGICA SINICA

Thioredoxin-1 Gene Therapy Enhances Angiogenic Signaling and Reduces Ventricular Remodeling in Infarcted Myocardium of Diabetic Rats

(2010) Samson Mathews Samuel et al.   CIRCULATION

Pretreatment with hyperoxia reduces in vivo infarct size and cell death by apoptosis with an early and delayed phase of protection

(2010) Mohsen Foadoddini et al.   EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY

Hearts of Hypoxia-inducible Factor Prolyl 4-Hydroxylase-2 Hypomorphic Mice Show Protection against Acute Ischemia-Reperfusion Injury

(2010) Jaana Hyvärinen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chronic Inhibition of Hypoxia-inducible Factor Prolyl 4-hydroxylase Improves Ventricular Performance, Remodeling, and Vascularity After Myocardial Infarction in the Rat

(2010) Weike Bao et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Inhibition of β-catenin/Tcf signaling by flavonoids

(2010) Seyeon Park et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Exogenous expression of HIF-1α promotes cardiac differentiation of embryonic stem cells

(2010) Kwong-Man Ng et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Nitric oxide and pathogenic mechanisms involved in the development of vascular diseases

(2009) Claudio Napoli et al.   ARCHIVES OF PHARMACAL RESEARCH

Coadministration of Adenoviral Vascular Endothelial Growth Factor and Angiopoietin-1 Enhances Vascularization and Reduces Ventricular Remodeling in the Infarcted Myocardium of Type 1 Diabetic Rats

(2009) S. M. Samuel et al.   DIABETES

Loss or Silencing of the PHD1 Prolyl Hydroxylase Protects Livers of Mice Against Ischemia/Reperfusion Injury

(2009) Martin Schneider et al.   GASTROENTEROLOGY

Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease

(2009) Peter Fraisl et al.   NATURE REVIEWS DRUG DISCOVERY

Bone marrow derived stromal cells modified by adenovirus-mediated HIF-1α double mutant protect cardiac myocytes against CoCl2-induced apoptosis

(2009) Yesong Wang et al.   TOXICOLOGY IN VITRO

In vivofunctions of the prolyl-4-hydroxylase domain oxygen sensors: direct route to the treatment of anaemia and the protection of ischaemic tissues

(2008) D. M. Katschinski   Acta Physiologica

Adeno-sh-β-Catenin Abolishes Ischemic Preconditioning–Mediated Cardioprotection by Downregulation of Its Target Genes VEGF, Bcl-2, and Survivin in Ischemic Rat Myocardium

(2008) Mahesh Thirunavukkarasu et al.   ANTIOXIDANTS & REDOX SIGNALING

Hypoxia-inducible factor-1alpha is a critical mediator of hypoxia induced apoptosis in cardiac H9c2 and kidney epithelial HK-2 cells

(2008) Ricky Malhotra et al.   BMC Cardiovascular Disorders

Hypoxia-Inducible Factor-1 Is Central to Cardioprotection

(2008) Tobias Eckle et al.   CIRCULATION

Akt/FOXO3a/SIRT1-Mediated Cardioprotection byn-Tyrosol against Ischemic Stress in Rat in Vivo Model of Myocardial Infarction: Switching Gears toward Survival and Longevity

(2008) Samson Mathews Samuel et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Heterozygous disruption of Flk-1 receptor leads to myocardial ischaemia reperfusion injury in mice: application of affymetrix gene chip analysis

(2008) M. Thirunavukkarasu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism

(2008) Julián Aragonés et al.   NATURE GENETICS