Genetic Risk Prediction: Individualized Variability in Susceptibility to Toxicants

Programming of DNA Methylation Patterns

(2012) Howard Cedar et al.   Annual Review of Biochemistry

Differential Expression of MicroRNAs in Different Disease States

(2012) Maha Abdellatif   CIRCULATION RESEARCH

Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits

(2012) Jian Yang et al.   NATURE GENETICS

Rare and common variants: twenty arguments

(2012) Greg Gibson   NATURE REVIEWS GENETICS

Chromatin replication and epigenome maintenance

(2012) Constance Alabert et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

PharmGKB summary

(2012) Ellen M. McDonagh et al.   Pharmacogenetics and Genomics

Individualized risk for statin-induced myopathy: current knowledge, emerging challenges and potential solutions

(2012) QiPing Feng et al.   PHARMACOGENOMICS

Genetic and Environmental Contributions to Weight, Height, and BMI from Birth to 19 Years of Age: An International Study of Over 12,000 Twin Pairs

(2012) Lise Dubois et al.   PLoS One

The mystery of missing heritability: Genetic interactions create phantom heritability

(2012) O. Zuk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role ofATG16L,NOD2andIL23Rin Crohn’s disease pathogenesis

(2012) Saleh A Naser   WORLD JOURNAL OF GASTROENTEROLOGY

Genetic Architecture of Highly Complex Chemical Resistance Traits across Four Yeast Strains

(2012) Ian M. Ehrenreich et al.   PLoS Genetics

Genome-Wide Association Study Identifies Chromosome 10q24.32 Variants Associated with Arsenic Metabolism and Toxicity Phenotypes in Bangladesh

(2012) Brandon L. Pierce et al.   PLoS Genetics

The Impact of Classification of Interest on Predictive Toxicogenomics

(2012) Robnet T. Kerns et al.   Frontiers in Genetics

Relationship between HLA-DRB1 polymorphism and susceptibility or resistance to multiple sclerosis in Caucasians: A meta-analysis of non-family-based studies

(2011) Qiong Zhang et al.   AUTOIMMUNITY REVIEWS

Recent advances in renal urate transport: characterization of candidate transporters indicated by genome-wide association studies

(2011) Naohiko Anzai et al.   Clinical and Experimental Nephrology

The challenge of predicting macular degeneration

(2011) Beatrix Feigl et al.   CURRENT MEDICAL RESEARCH AND OPINION

Environmental epigenomics and disease susceptibility

(2011) Michael K Skinner   EMBO REPORTS

HGV2011: Personalized genomic medicine meets the incidentalome

(2011) Melissa A. Wilson Sayres et al.   HUMAN MUTATION

Initial impact of the sequencing of the human genome

(2011) Eric S. Lander   NATURE

Next-generation association studies for complex traits

(2011) Eleftheria Zeggini   NATURE GENETICS

Identification of low-frequency variants associated with gout and serum uric acid levels

(2011) Patrick Sulem et al.   NATURE GENETICS

Genome partitioning of genetic variation for complex traits using common SNPs

(2011) Jian Yang et al.   NATURE GENETICS

Epigenome-wide association studies for common human diseases

(2011) Vardhman K. Rakyan et al.   NATURE REVIEWS GENETICS

Exome sequencing as a tool for Mendelian disease gene discovery

(2011) Michael J. Bamshad et al.   NATURE REVIEWS GENETICS

The Importance of Synthetic Associations Will Only Be Resolved Empirically

(2011) David B. Goldstein   PLOS BIOLOGY

Synthetic Associations Created by Rare Variants Do Not Explain Most GWAS Results

(2011) Naomi R. Wray et al.   PLOS BIOLOGY

Synthetic Associations Are Unlikely to Account for Many Common Disease Genome-Wide Association Signals

(2011) Carl A. Anderson et al.   PLOS BIOLOGY

Genome-Wide Meta-Analysis Identifies Regions on 7p21 (AHR) and 15q24 (CYP1A2) As Determinants of Habitual Caffeine Consumption

(2011) Marilyn C. Cornelis et al.   PLoS Genetics

Common Variants Show Predicted Polygenic Effects on Height in the Tails of the Distribution, Except in Extremely Short Individuals

(2011) Yingleong Chan et al.   PLoS Genetics

DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines

(2011) Jordana T Bell et al.   GENOME BIOLOGY

Hepatitis C pharmacogenetics: State of the art in 2010

(2010) Nezam H. Afdhal et al.   HEPATOLOGY

Genetic risk sum score comprised of common polygenic variation is associated with body mass index

(2010) Roseann E. Peterson et al.   HUMAN GENETICS

Clinical assessment incorporating a personal genome

(2010) Euan A Ashley et al.   LANCET

Epigenetics as a unifying principle in the aetiology of complex traits and diseases

(2010) Arturas Petronis   NATURE

Hundreds of variants clustered in genomic loci and biological pathways affect human height

(2010) Hana Lango Allen et al.   NATURE

Hints of hidden heritability in GWAS

(2010) Greg Gibson   NATURE GENETICS

Estimation of effect size distribution from genome-wide association studies and implications for future discoveries

(2010) Ju-Hyun Park et al.   NATURE GENETICS

Common SNPs explain a large proportion of the heritability for human height

(2010) Jian Yang et al.   NATURE GENETICS

Statistical interaction in human genetics: how should we model it if we are looking for biological interaction?

(2010) Xuefeng Wang et al.   NATURE REVIEWS GENETICS

Genome-wide association studies in diverse populations

(2010) Noah A. Rosenberg et al.   NATURE REVIEWS GENETICS

Uncovering the roles of rare variants in common disease through whole-genome sequencing

(2010) Elizabeth T. Cirulli et al.   NATURE REVIEWS GENETICS

Genomewide Association Studies and Assessment of the Risk of Disease

(2010) Teri A. Manolio   NEW ENGLAND JOURNAL OF MEDICINE

Chipping Away the ‘Missing Heritability’: GIANT Steps Forward in the Molecular Elucidation of Obesity – but Still Lots to Go

(2010) Johannes Hebebrand et al.   Obesity Facts

Examination of All Type 2 Diabetes GWAS Loci Reveals HHEX-IDE as a Locus Influencing Pediatric BMI

(2009) J. Zhao et al.   DIABETES

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

DNA methylation profiles in monozygotic and dizygotic twins

(2009) Zachary A Kaminsky et al.   NATURE GENETICS

Decanalization and the origin of complex disease

(2009) Greg Gibson   NATURE REVIEWS GENETICS

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

(2009) L. A. Hindorff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Life After GWA Studies

(2009) E. T. Dermitzakis et al.   SCIENCE

Interpretation of Genetic Association Studies: Markers with Replicated Highly Significant Odds Ratios May Be Poor Classifiers

(2009) Johanna Jakobsdottir et al.   PLoS Genetics

A Genome-Wide Investigation of SNPs and CNVs in Schizophrenia

(2009) Anna C. Need et al.   PLoS Genetics

From Human Genetics and Genomics to Pharmacogenetics and Pharmacogenomics: Past Lessons, Future Directions

(2008) Daniel W. Nebert et al.   DRUG METABOLISM REVIEWS

Genome-wide association analysis identifies 20 loci that influence adult height

(2008) Michael N Weedon et al.   NATURE GENETICS

Many sequence variants affecting diversity of adult human height

(2008) Daniel F Gudbjartsson et al.   NATURE GENETICS

Identification of ten loci associated with height highlights new biological pathways in human growth

(2008) Guillaume Lettre et al.   NATURE GENETICS

Genome-wide association studies for complex traits: consensus, uncertainty and challenges

(2008) Mark I. McCarthy et al.   NATURE REVIEWS GENETICS

Data and Theory Point to Mainly Additive Genetic Variance for Complex Traits

(2008) William G. Hill et al.   PLoS Genetics