On the specificity of antibiotics targeting the large ribosomal subunit

Linezolid, the first oxazolidinone antibacterial agent

(2011) Karen L. Leach et al.   Annals of the New York Academy of Sciences

Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit

(2011) M. J. Belousoff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SecM-Stalled Ribosomes Adopt an Altered Geometry at the Peptidyl Transferase Center

(2011) Shashi Bhushan et al.   PLOS BIOLOGY

Binding and Action of CEM-101, a New Fluoroketolide Antibiotic That Inhibits Protein Synthesis

(2010) B. Llano-Sotelo et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Interplay between the Ribosomal Tunnel, Nascent Chain, and Macrolides Influences Drug Inhibition

(2010) Agata L. Starosta et al.   CHEMISTRY & BIOLOGY

Structural Basis for Translational Stalling by Human Cytomegalovirus and Fungal Arginine Attenuator Peptide

(2010) Shashi Bhushan et al.   MOLECULAR CELL

Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action

(2010) J. A. Dunkle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Revisiting the structures of several antibiotics bound to the bacterial ribosome

(2010) D. Bulkley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structures of Triacetyloleandomycin and Mycalamide A Bind to the Large Ribosomal Subunit of Haloarcula marismortui

(2009) G. Gurel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Distinct Mode of Interaction of a Novel Ketolide Antibiotic That Displays Enhanced Antimicrobial Activity

(2009) E. C. Kouvela et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Enhanced SnapShot: Antibiotic Inhibition of Protein Synthesis II

(2009) Daniel Sohmen et al.   CELL

The A–Z of bacterial translation inhibitors

(2009) Daniel N. Wilson   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

U2504 Determines the Species Specificity of the A-Site Cleft Antibiotics:

(2009) Güliz Gürel et al.   JOURNAL OF MOLECULAR BIOLOGY

What recent ribosome structures have revealed about the mechanism of translation

(2009) T. Martin Schmeing et al.   NATURE

Structural Insight into Nascent Polypeptide Chain-Mediated Translational Stalling

(2009) B. Seidelt et al.   SCIENCE

R -01, a New Family of Oxazolidinones That Overcome Ribosome-Based Linezolid Resistance

(2008) E. Skripkin et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Macrolide myths

(2008) Alexander S Mankin   CURRENT OPINION IN MICROBIOLOGY

Crystal Structure of the Oxazolidinone Antibiotic Linezolid Bound to the 50S Ribosomal Subunit∥

(2008) Joseph A. Ippolito et al.   JOURNAL OF MEDICINAL CHEMISTRY

Time-Resolved Binding of Azithromycin to Escherichia coli Ribosomes

(2008) Alexandros D. Petropoulos et al.   JOURNAL OF MOLECULAR BIOLOGY

Translational Regulation via L11: Molecular Switches on the Ribosome Turned On and Off by Thiostrepton and Micrococcin

(2008) Joerg M. Harms et al.   MOLECULAR CELL

The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning

(2008) D. N. Wilson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA