The metabolic syndrome and neuropathy: Therapeutic challenges and opportunities

The Effects of Salsalate on Glycemic Control in Patients With Type 2 Diabetes

(2013) Allison B. Goldfine   ANNALS OF INTERNAL MEDICINE

JNK inhibitors as anti-inflammatory and neuroprotective agents

(2013) Piotr P Graczyk   Future Medicinal Chemistry

Rapalogs and mTOR inhibitors as anti-aging therapeutics

(2013) Dudley W. Lamming et al.   JOURNAL OF CLINICAL INVESTIGATION

Anti-Inflammatory Therapy in Chronic Disease: Challenges and Opportunities

(2013) I. Tabas et al.   SCIENCE

Pleiotropic Actions of Insulin Resistance and Inflammation in Metabolic Homeostasis

(2013) J. I. Odegaard et al.   SCIENCE

Diabetic cardiac autonomic neuropathy, inflammation and cardiovascular disease

(2013) Aaron I Vinik et al.   Journal of Diabetes Investigation

Blockade of XBP1 splicing by inhibition of IRE1  is a promising therapeutic option in multiple myeloma

(2012) N. Mimura et al.   BLOOD

Mechanisms for Insulin Resistance: Common Threads and Missing Links

(2012) Varman T. Samuel et al.   CELL

The role of mTOR signaling pathway in spinal cord injury

(2012) Haruo Kanno et al.   CELL CYCLE

Diabetic neuropathy

(2012) Brian C. Callaghan et al.   CURRENT OPINION IN NEUROLOGY

Endoplasmic reticulum stress contributes to prediabetic peripheral neuropathy

(2012) Sergey Lupachyk et al.   EXPERIMENTAL NEUROLOGY

Decreased glycolytic and tricarboxylic acid cycle intermediates coincide with peripheral nervous system oxidative stress in a murine model of type 2 diabetes

(2012) Lucy M Hinder et al.   JOURNAL OF ENDOCRINOLOGY

Bioenergetics in diabetic neuropathy: what we need to know

(2012) Lucy M. Hinder et al.   JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM

Diabetic neuropathy: clinical manifestations and current treatments

(2012) Brian C Callaghan et al.   LANCET NEUROLOGY

Fetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin resistance

(2012) Durba Pal et al.   NATURE MEDICINE

Kinases and kinase signaling pathways: Potential therapeutic targets in Parkinson's disease

(2012) Gang Wang et al.   PROGRESS IN NEUROBIOLOGY

Metformin, Independent of AMPK, Induces mTOR Inhibition and Cell-Cycle Arrest through REDD1

(2011) I. Ben Sahra et al.   CANCER RESEARCH

Prevalence and Characteristics of Painful Diabetic Neuropathy in a Large Community-Based Diabetic Population in the U.K.

(2011) C. A. Abbott et al.   DIABETES CARE

Novel C-C chemokine receptor 2 antagonists in metabolic disease: a review of recent developments

(2011) Young Sun Kang et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Potent and Selective Inhibitors of the Inositol-requiring Enzyme 1 Endoribonuclease

(2011) Kori Volkmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Impaired sensory nerve function and axon morphology in mice with diabetic neuropathy

(2011) Richard C. Lennertz et al.   JOURNAL OF NEUROPHYSIOLOGY

National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9·1 million participants

(2011) Mariel M Finucane et al.   LANCET

Diabetic neuropathy: cellular mechanisms as therapeutic targets

(2011) Andrea M. Vincent et al.   Nature Reviews Neurology

Nerve growth factor/p38 signaling increases intraepidermal nerve fiber densities in painful neuropathy of type 2 diabetes

(2011) Hsinlin T. Cheng et al.   NEUROBIOLOGY OF DISEASE

Potential Role of Salicylates in Type 2 Diabetes

(2010) Martha M Rumore et al.   ANNALS OF PHARMACOTHERAPY

Macrophages, Inflammation, and Insulin Resistance

(2010) Jerrold M. Olefsky et al.   Annual Review of Physiology

Prevalence of the metabolic syndrome in Pudong New Area of Shanghai using three proposed definitions among Chinese adults

(2010) Wang-hong Xu et al.   BMC PUBLIC HEALTH

Metformin, Independent of AMPK, Inhibits mTORC1 in a Rag GTPase-Dependent Manner

(2010) Adem Kalender et al.   Cell Metabolism

Effect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial

(2010) Faramarz Ismail-Beigi et al.   LANCET

Elevated Triglycerides Correlate With Progression of Diabetic Neuropathy

(2009) T. D. Wiggin et al.   DIABETES

Prevalence and impact on quality of life of peripheral neuropathy with or without neuropathic pain in type 1 and type 2 diabetic patients attending hospital outpatients clinics

(2009) K. Van Acker et al.   DIABETES & METABOLISM

Subclinical Inflammation and Diabetic Polyneuropathy: MONICA/KORA Survey F3 (Augsburg, Germany)

(2009) C. Herder et al.   DIABETES CARE

Role of Chemokines in CNS Health and Pathology: A Focus on the CCL2/CCR2 and CXCL8/CXCR2 Networks

(2009) Bridgette D Semple et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Microvascular Reactivity and Inflammatory Cytokines in Painful and Painless Peripheral Diabetic Neuropathy

(2009) John Doupis et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Hyperlipidemia: a new therapeutic target for diabetic neuropathy

(2009) Andrea M. Vincent et al.   JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM

Prevalence of metabolic syndrome and factors associated with its components in Chinese adults

(2009) Hui Zuo et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Idiopathic neuropathy patients are at high risk for metabolic syndrome

(2008) A. Gordon Smith et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Glucose Control and Vascular Complications in Veterans with Type 2 Diabetes

(2008) William Duckworth et al.   NEW ENGLAND JOURNAL OF MEDICINE