Advancing management of hypertension through pharmacogenomics

Cardiovascular Pharmacogenomics of Adrenergic Receptor Signaling: Clinical Implications and Future Directions

(2011) J A Johnson et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Do Genetic Variants of the Renin-Angiotensin System Predict Blood Pressure Response to Renin-Angiotensin System–Blocking Drugs? A Systematic Review of Pharmacogenomics in the Renin-Angiotensin System

(2011) Tadashi Konoshita et al.   CURRENT HYPERTENSION REPORTS

Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study

(2011) Ervin R. Fox et al.   HUMAN MOLECULAR GENETICS

Association of Hypertension Drug Target Genes With Blood Pressure and Hypertension in 86 588 Individuals

(2011) Andrew D. Johnson et al.   HYPERTENSION

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

(2011) Georg B. Ehret et al.   NATURE

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

(2011) Louise V Wain et al.   NATURE GENETICS

Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians

(2011) Norihiro Kato et al.   NATURE GENETICS

Plasma Renin Activity Predicts Blood Pressure Responses to  -Blocker and Thiazide Diuretic as Monotherapy and Add-On Therapy for Hypertension

(2010) S. T. Turner et al.   AMERICAN JOURNAL OF HYPERTENSION

Association Between NEDD4L Gene and Sodium Lithium Countertransport

(2010) Xiaojing Zheng et al.   AMERICAN JOURNAL OF HYPERTENSION

Genetic Variation in the β2 Subunit of the Voltage-Gated Calcium Channel and Pharmacogenetic Association With Adverse Cardiovascular Outcomes in the INternational VErapamil SR-Trandolapril STudy GENEtic Substudy (INVEST-GENES)

(2010) Yuxin Niu et al.   Circulation-Cardiovascular Genetics

Genetic determinants of treatment benefit of the angiotensin-converting enzyme-inhibitor perindopril in patients with stable coronary artery disease

(2010) Jasper Jan Brugts et al.   EUROPEAN HEART JOURNAL

A functional variant of the NEDD4L gene is associated with beneficial treatment response with β-blockers and diuretics in hypertensive patients

(2010) Patrik Svensson-Färbom et al.   JOURNAL OF HYPERTENSION

Common genetic variation of β1- and β2-adrenergic receptor and response to four classes of antihypertensive treatment

(2010) Timo Suonsyrjä et al.   Pharmacogenetics and Genomics

Pharmacogenetic Effect of the Stromelysin (MMP3) Polymorphism on Stroke Risk in Relation to Antihypertensive Treatment

(2010) Richard Sherva et al.   STROKE

Pharmacogenomics of antihypertensive drugs: Rationale and design of the Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) study

(2009) Julie A. Johnson et al.   AMERICAN HEART JOURNAL

A Functional Variant of NEDD4L Is Associated With Hypertension, Antihypertensive Response, and Orthostatic Hypotension

(2009) Fang Luo et al.   HYPERTENSION

Human Nedd4L rs4149601 G Allele Generates Evolutionary New Isoform I With C2 Domain

(2009) Tomoaki Ishigami et al.   HYPERTENSION

Blood pressure control and physicians’ therapeutic behavior in a very elderly Spanish hypertensive population

(2009) Gustavo C Rodríguez-Roca et al.   HYPERTENSION RESEARCH

Antihypertensive drug therapy and blood pressure control in men and women: an international perspective

(2009) M Thoenes et al.   JOURNAL OF HUMAN HYPERTENSION

Genome-wide association study identifies eight loci associated with blood pressure

(2009) Christopher Newton-Cheh et al.   NATURE GENETICS

Genome-wide association study of blood pressure and hypertension

(2009) Daniel Levy et al.   NATURE GENETICS

 1- and  2-Adrenergic Receptor Gene Variation,  -Blocker Use and Risk of Myocardial Infarction and Stroke

(2008) R. N. Lemaitre et al.   AMERICAN JOURNAL OF HYPERTENSION

β-Adrenergic Receptor Gene Polymorphisms and β-Blocker Treatment Outcomes in Hypertension

(2008) MA Pacanowski et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Screening, Treatment, and Control of Hypertension in US Private Physician Offices, 2003–2004

(2008) Jun Ma et al.   HYPERTENSION

Genomic Association Analysis Suggests Chromosome 12 Locus Influencing Antihypertensive Response to Thiazide Diuretic

(2008) Stephen T. Turner et al.   HYPERTENSION