The Asymmetric Hetero-Diels-Alder Reaction in the Syntheses of Biologically Relevant Compounds

An Enantioselective Inverse-Electron-Demand Imino Diels-Alder Reaction

(2014) Vincent Eschenbrenner-Lux et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Treatment with Pyranopyran-1, 8-Dione Attenuates Airway Responses in Cockroach Allergen Sensitized Asthma in Mice

(2014) Soojin Park et al.   PLoS One

Complex Bioactive Alkaloid-Type Polycycles through Efficient Catalytic Asymmetric Multicomponent Aza-Diels-Alder Reaction of Indoles with Oxetane as Directing Group

(2013) Zhilong Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Industrial Applications of the Diels-Alder Reaction

(2013) Jacques-Alexis Funel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cascade Syntheses Routes to the Centrocountins

(2013) Vincent Eschenbrenner-Lux et al.   CHEMISTRY-A EUROPEAN JOURNAL

Concise Synthesis and Biological Assessment of (+)-Neopeltolide and a 16-Member Stereoisomer Library of 8,9-Dehydroneopeltolide: Identification of Pharmacophoric Elements

(2013) Haruhiko Fuwa et al.   CHEMISTRY-A EUROPEAN JOURNAL

Bioinspired Total Synthesis of Bolivianine: A Diels– Alder/Intramolecular Hetero-Diels–Alder Cascade Approach

(2013) Changchun Yuan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective total synthesis of macrolide (+)-neopeltolide

(2013) Arun K. Ghosh et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Application of 2,4,6-trioxo-pyrimidin-5-ylidene alditols in the synthesis of pyrano[2,3-d]pyrimidines containing a sugar moiety by hetero-Diels–Alder reactions and by conjugate Michael addition–cyclizations

(2013) Aleksandra Pałasz et al.   TETRAHEDRON

Asymmetric synthesis of (−)-bissetone via a highly enantioselective hetero-Diels–Alder reaction

(2013) Jakub Majer et al.   TETRAHEDRON

Enantio- and diastereoselective hetero-Diels–Alder reactions between 4-methyl-substituted Rawal’s diene and aldehydes catalyzed by chiral dirhodium(II) carboxamidates: catalytic asymmetric synthesis of (−)-cis-aerangis lactone

(2013) Yudai Watanabe et al.   TETRAHEDRON-ASYMMETRY

On the Origin of Single Chirality of Amino Acids and Sugars in Biogenesis

(2012) Jason E. Hein et al.   ACCOUNTS OF CHEMICAL RESEARCH

Catalytic enantioselective [4 + 2]-cycloaddition: a strategy to access aza-hexacycles

(2012) Géraldine Masson et al.   CHEMICAL SOCIETY REVIEWS

Iminium Ions as Dienophiles in Aza-Diels-Alder Reactions: A Closer Look

(2012) Misal Giuseppe Memeo et al.   CHEMISTRY-A EUROPEAN JOURNAL

Chiral Phosphoric Acid Catalyzed Inverse-Electron-Demand Aza-Diels–Alder Reaction of Isoeugenol Derivatives

(2012) Long He et al.   ORGANIC LETTERS

Application of a Catalytic Asymmetric Povarov Reaction using Chiral Ureas to the Synthesis of a Tetrahydroquinoline Library

(2012) Baudouin Gerard et al.   ACS Combinatorial Science

Step-Economical Synthesis of Tetrahydroquinolines by Asymmetric Relay Catalytic Friedländer Condensation/Transfer Hydrogenation

(2011) Lei Ren et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Synthesis of Tetrahydroquinolines with Quaternary Stereocenters through the Povarov Reaction

(2011) Mingsheng Xie et al.   CHEMISTRY-A EUROPEAN JOURNAL

Carbohydrates and Immunology: Synthetic Oligosaccharide Antigens for Vaccine Formulation

(2011) Laura Morelli et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Biocatalytic Promiscuity

(2011) Maria Svedendahl Humble et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Enzyme-Catalyzed Direct Three-Component Aza-Diels–Alder Reaction Using Hen Egg White Lysozyme

(2011) Yan-Hong He et al.   JOURNAL OF ORGANIC CHEMISTRY

Enzyme-catalysed [4+2] cycloaddition is a key step in the biosynthesis of spinosyn A

(2011) Hak Joong Kim et al.   NATURE

Natural product–inspired cascade synthesis yields modulators of centrosome integrity

(2011) Heiko Dückert et al.   Nature Chemical Biology

What makes an enzyme promiscuous?

(2010) Ann Babtie et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Human Cytochrome P450 Liability Studies oftrans-Dihydronarciclasine: A Readily Available, Potent, and Selective Cancer Cell Growth Inhibitor

(2010) James McNulty et al.   JOURNAL OF NATURAL PRODUCTS

Anguinomycins and Derivatives: Total Syntheses, Modeling, and Biological Evaluation of the Inhibition of Nucleocytoplasmic Transport

(2010) Simone Bonazzi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Role of Complex Carbohydrates in Human Immunodeficiency Virus Type 1 Infection and Resistance to Antibody Neutralization

(2010) J. M. Binley et al.   JOURNAL OF VIROLOGY

Theoretical Investigation of the Rubicordifolin Cascade

(2010) Jean-Philip Lumb et al.   ORGANIC LETTERS

Asymmetric Cooperative Catalysis of Strong Bronsted Acid-Promoted Reactions Using Chiral Ureas

(2010) H. Xu et al.   SCIENCE

Domino Knoevenagel–hetero-Diels–Alder reactions: a stereoselective synthesis of sugar-annulated furo[3,2-b] pyrano[4,3-d]pyran derivatives

(2010) J.S. Yadav et al.   TETRAHEDRON LETTERS

Recent Advances in Monosaccharide Synthesis: A Journey into L-Hexose World

(2009) Daniele D'Alonzo et al.   CURRENT ORGANIC CHEMISTRY

A Flexible Enantioselective Total Synthesis of Diospongins A and B and Their Enantiomers Using Catalytic Hetero-Diels−Alder/Rh-Catalyzed 1,4-Addition and Asymmetric Transfer Hydrogenation Reactions as Key Steps

(2009) Gullapalli Kumaraswamy et al.   JOURNAL OF ORGANIC CHEMISTRY

Total Synthesis of (−)-Platensimycin, a Novel Antibacterial Agent

(2009) Arun K. Ghosh et al.   JOURNAL OF ORGANIC CHEMISTRY

New Syntheses of E7389 C14−C35 and Halichondrin C14−C38 Building Blocks: Double-Inversion Approach

(2009) Dae-Shik Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chiral Brønsted Acid-Catalyzed Enantioselective Three-Component Povarov Reaction

(2009) Hua Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Synthesis of (+)-trans-Dihydronarciclasine by a Catalytic Enantioselective Regiodivergent Nitroso Diels-Alder Reaction

(2008) Chandan Kumar Jana et al.   CHEMISTRY-A EUROPEAN JOURNAL

Stereoselective Synthesis of (+)-Goniodiol, (+)-Goniotriol, (-)-Goniofupyrone, and (+)-Altholactone Using a Catalytic Asymmetric Hetero-Diels-Alder/Allylboration Approach

(2008) Annaïck Favre et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Total Synthesis of (+)-Azaspiracid-1. An Exhibition of the Intricacies of Complex Molecule Synthesis

(2008) David A. Evans et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Azaspiracid Shellfish Poisoning: A Review on the Chemistry, Ecology, and Toxicology with an Emphasis on Human Health Impacts

(2008) Michael Twiner et al.   Marine Drugs