Copper-Catalyzed Site-Selective Intramolecular Amidation of Unactivated C(sp3)H Bonds

Nickel-Catalyzed Site-Selective Alkylation of Unactivated C(sp3)–H Bonds

(2014) Xuesong Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Class D β-Lactamases: A Reappraisal after Five Decades

(2013) David A. Leonard et al.   ACCOUNTS OF CHEMICAL RESEARCH

Stereoselective Synthesis of Chiral α-Amino-β-Lactams through Palladium(II)-Catalyzed Sequential Monoarylation/Amidation of C(sp3)H Bonds

(2013) Qi Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Directed Amination of Non-Acidic Arene CH Bonds by a Copper-Silver Catalytic System

(2013) Ly Dieu Tran et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Use of a Readily Removable Auxiliary Group for the Synthesis of Pyrrolidones by the Palladium-Catalyzed Intramolecular Amination of Unactivated γ C(sp3)H Bonds

(2013) Gang He et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Functionalization of C(sp2)H and C(sp3)H Bonds by Using Bidentate Directing Groups

(2013) Guy Rouquet et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Origins of the β-lactam rings in natural products

(2013) Kapil Tahlan et al.   JOURNAL OF ANTIBIOTICS

β-Arylation of Carboxamides via Iron-Catalyzed C(sp3)–H Bond Activation

(2013) Rui Shang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed, Directing Group-Assisted Fluorination of Arene and Heteroarene C–H Bonds

(2013) Thanh Truong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Divergence between Organometallic and Single-Electron-Transfer Mechanisms in Copper(II)-Mediated Aerobic C–H Oxidation

(2013) Alison M. Suess et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Picolinamide-Directed Alkylation of Unactivated C(sp3)–H Bonds with Alkyl Iodides

(2013) Shu-Yu Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

β-Lactamase Inhibitors: An Update

(2013) Jiao Chen et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Palladium-Catalyzed Unactivated C(sp3)–H Bond Activation and Intramolecular Amination of Carboxamides: A New Approach to β-Lactams

(2013) Wen-Wu Sun et al.   ORGANIC LETTERS

Copper-Catalyzed Etherification of Arene C–H Bonds

(2013) James Roane et al.   ORGANIC LETTERS

3,3-gem-Difluorinated-β-lactams: synthesis pathways and applications

(2013) Thomas Orbegozo et al.   TETRAHEDRON

Ruthenium-catalyzed cyclocarbonylation of aliphatic amides through the regioselective activation of unactivated C(sp3)–H bonds

(2013) Nao Hasegawa et al.   TETRAHEDRON

Pd(ii)-catalyzed alkylation of unactivated C(sp3)–H bonds: efficient synthesis of optically active unnatural α-amino acids

(2013) Kai Chen et al.   Chemical Science

On the Interpretation of Deuterium Kinetic Isotope Effects in CH Bond Functionalizations by Transition-Metal Complexes

(2012) Eric M. Simmons et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Oxazoles through Copper-Mediated Aerobic Oxidative Dehydrogenative Annulation and Oxygenation of Aldehydes and Amines

(2012) Zejun Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nonnatural Amino Acid Synthesis by Using Carbon-Hydrogen Bond Functionalization Methodology

(2012) Ly Dieu Tran et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent advances in copper-catalyzed dehydrogenative functionalization via a single electron transfer (SET) process

(2012) Chun Zhang et al.   CHEMICAL SOCIETY REVIEWS

Anticancer Drug Design Using Scaffolds of β-Lactams, Sulfonamides, Quinoline, Quinoxaline and Natural Products. Drugs Advances in Clinical Trials

(2012) I. Balderas-Renteria et al.   CURRENT MEDICINAL CHEMISTRY

Reappraising the use of β-lactams to treat tuberculosis

(2012) Sebastian G Kurz et al.   Expert Review of Anti-Infective Therapy

Copper-Catalyzed Aerobic [3+2]-Annulation of N-Alkenyl Amidines

(2012) Yi-Feng Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed Aerobic Aliphatic C–H Oxygenation Directed by an Amidine Moiety

(2012) Yi-Feng Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Promoted Sulfenylation of sp2 C–H Bonds

(2012) Ly Dieu Tran et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pd(II)-Catalyzed Primary-C(sp3)–H Acyloxylation at Room Temperature

(2012) Raja K. Rit et al.   ORGANIC LETTERS

Copper-Catalyzed Aliphatic C–H Amination with an Amidine Moiety

(2012) Hui Chen et al.   ORGANIC LETTERS

Adding Aliphatic C-H Bond Oxidations to Synthesis

(2012) M. C. White   SCIENCE

Advances in the chemistry of ?-lactam and its medicinal applications

(2012) Anushree Kamath et al.   TETRAHEDRON

Palladium-catalyzed N-(2-pyridyl)sulfonyl-directed C(sp3)–H γ-arylation of amino acid derivatives

(2012) Nuria Rodríguez et al.   Chemical Science

Rhodium Catalyzed Chelation-Assisted C–H Bond Functionalization Reactions

(2011) Denise A. Colby et al.   ACCOUNTS OF CHEMICAL RESEARCH

A Practical Strategy for the Structural Diversification of Aliphatic Scaffolds through the Palladium-Catalyzed Picolinamide-Directed Remote Functionalization of Unactivated C(sp3)H Bonds

(2011) Gang He et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Catalyzed Intramolecular Dehydrogenative Aminooxygenation: Direct Access to Formyl-Substituted Aromatic N-Heterocycles

(2011) Honggen Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

If CH Bonds Could Talk: Selective CH Bond Oxidation

(2011) Timothy Newhouse et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Catalyzed Aerobic Oxidative CH Functionalizations: Trends and Mechanistic Insights

(2011) Alison E. Wendlandt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bond Formations between Two Nucleophiles: Transition Metal Catalyzed Oxidative Cross-Coupling Reactions

(2011) Chao Liu et al.   CHEMICAL REVIEWS

Catalytic Dehydrogenative Cross-Coupling: Forming Carbon−Carbon Bonds by Oxidizing Two Carbon−Hydrogen Bonds

(2011) Charles S. Yeung et al.   CHEMICAL REVIEWS

C–H Functionalization in organic synthesis

(2011) Huw M. L. Davies et al.   CHEMICAL SOCIETY REVIEWS

C–H functionalization logic in total synthesis

(2011) Will R. Gutekunst et al.   CHEMICAL SOCIETY REVIEWS

Transition metal-catalyzed arylation of unactivated C(sp3)–H bonds

(2011) Olivier Baudoin   CHEMICAL SOCIETY REVIEWS

Regioselectivity of the borylation of alkanes and arenes

(2011) John F. Hartwig   CHEMICAL SOCIETY REVIEWS

Observation and Mechanistic Study of Facile CO Bond Formation between a Well-Defined Aryl-Copper(III) Complex and Oxygen Nucleophiles

(2011) Lauren M. Huffman et al.   CHEMISTRY-A EUROPEAN JOURNAL

Monocyclic β-Lactams: New Structures for New Biological Activities

(2011) P. Galletti et al.   CURRENT MEDICINAL CHEMISTRY

Revisiting Beta-lactams – PK/PD improves dosing of old antibiotics

(2011) Alasdair MacGowan   CURRENT OPINION IN PHARMACOLOGY

Functionalization of Saturated and Unsaturated Heterocycles via Transition Metal Catalyzed C-H Activation Reactions

(2011) Michael Schnurch et al.   CURRENT ORGANIC CHEMISTRY

Highly Regioselective Carbonylation of Unactivated C(sp3)–H Bonds by Ruthenium Carbonyl

(2011) Nao Hasegawa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Direct Ethynylation of C(sp3)–H Bonds in Aliphatic Carboxylic Acid Derivatives

(2011) Yusuke Ano et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Heterocycle Synthesis via Direct C–H/N–H Coupling

(2011) Enrico T. Nadres et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Efficient Syntheses of Azetidines, Pyrrolidines, and Indolines via Palladium Catalyzed Intramolecular Amination of C(sp3)–H and C(sp2)–H Bonds at γ and δ Positions

(2011) Gang He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Mediated Aerobic Synthesis of 3-Azabicyclo[3.1.0]hex-2-enes and 4-Carbonylpyrroles fromN-Allyl/Propargyl Enamine Carboxylates

(2011) Kah Kah Toh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Mediated Chelation-AssistedOrthoNitration of (Hetero)arenes

(2011) Lin Zhang et al.   ORGANIC LETTERS

Palladium-Catalyzed Direct ortho-Alkynylation of Aromatic Carboxylic Acid Derivatives

(2011) Yusuke Ano et al.   ORGANIC LETTERS

Cobalt-Catalyzed, Chelation-Assisted C-H Bond Functionalization

(2011) Naohiko Yoshikai   SYNLETT

Synthesis and reactivity of spiro-fused β-lactams

(2011) Girija S. Singh et al.   TETRAHEDRON

Challenge and progress: palladium-catalyzed sp3 C–H activation

(2011) Hu Li et al.   Catalysis Science & Technology

Copper-Catalyzed Aerobic Oxidative Dehydrogenative Coupling of Anilines Leading to Aromatic Azo Compounds using Dioxygen as an Oxidant

(2010) Chun Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Metal-catalyzed direct alkylations of (hetero)arenes via C–H bond cleavages with unactivated alkyl halides

(2010) Lutz Ackermann   CHEMICAL COMMUNICATIONS

Palladium-Catalyzed Ligand-Directed C−H Functionalization Reactions

(2010) Thomas W. Lyons et al.   CHEMICAL REVIEWS

Functionalization of Organic Molecules by Transition-Metal-Catalyzed C(sp3)H Activation

(2010) Rodolphe Jazzar et al.   CHEMISTRY-A EUROPEAN JOURNAL

Beyond Traditional Cross Couplings: The Scope of the Cross Dehydrogenative Coupling Reaction

(2010) Caroline J. Scheuermann   Chemistry-An Asian Journal

Cross-Coupling of C(sp3)-H Bonds with Organometallic Reagents via Pd(II)/Pd(0) Catalysis

(2010) Masayuki Wasa et al.   ISRAEL JOURNAL OF CHEMISTRY

A Direct Intramolecular C−H Amination Reaction Cocatalyzed by Copper(II) and Iron(III) as Part of an Efficient Route for the Synthesis of Pyrido[1,2-a]benzimidazoles fromN-Aryl-2-aminopyridines

(2010) Honggen Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Auxiliary-Assisted Palladium-Catalyzed Arylation and Alkylation of sp2and sp3Carbon−Hydrogen Bonds

(2010) Dmitry Shabashov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed Aerobic Oxidative Functionalization of an Arene C−H Bond: Evidence for an Aryl-Copper(III) Intermediate

(2010) Amanda E. King et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Facile C−H Bond Cleavage via a Proton-Coupled Electron Transfer Involving a C−H···CuIIInteraction

(2010) Xavi Ribas et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium- and Copper-Catalyzed Arylation of Carbon−Hydrogen Bonds

(2009) Olafs Daugulis et al.   ACCOUNTS OF CHEMICAL RESEARCH

Palladium(II)-Catalyzed CH Activation/CC Cross-Coupling Reactions: Versatility and Practicality

(2009) Xiao Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-catalyzed aerobic phosphonation of sp3 C–H bonds

(2009) Olivier Baslé et al.   CHEMICAL COMMUNICATIONS

Room-temperature aerobic formation of a stable aryl–Cu(iii) complex and its reactions with nucleophiles: highly efficient and diverse arene C–H functionalizations of azacalix[1]arene[3]pyridine

(2009) Bo Yao et al.   CHEMICAL COMMUNICATIONS

Copper-Catalyzed Synthesis of Benzoxazoles via a Regioselective C−H Functionalization/C−O Bond Formation under an Air Atmosphere

(2009) Satoshi Ueda et al.   JOURNAL OF ORGANIC CHEMISTRY

Facile Synthesis of 1,2,4-Triazoles via a Copper-Catalyzed Tandem Addition−Oxidative Cyclization

(2009) Satoshi Ueda et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dioxygen Activation under Ambient Conditions: Cu-Catalyzed Oxidative Amidation−Diketonization of Terminal Alkynes Leading to α-Ketoamides

(2009) Chun Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cross-Dehydrogenative Coupling (CDC): Exploring C−C Bond Formations beyond Functional Group Transformations

(2008) Chao-Jun Li   ACCOUNTS OF CHEMICAL RESEARCH

Synthesis of 2-Arylbenzoxazoles by Copper-Catalyzed Intramolecular Oxidative CO Coupling of Benzanilides

(2008) Satoshi Ueda et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

CH Functionalization/CN Bond Formation: Copper-Catalyzed Synthesis of Benzimidazoles from Amidines

(2008) Gordon Brasche et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Catalyzed Aerobic Oxidative Amidation of Terminal Alkynes:  Efficient Synthesis of Ynamides

(2008) Tetsuya Hamada et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of β-, γ-, and δ-Lactams via Pd(II)-Catalyzed C−H Activation Reactions

(2008) Masayuki Wasa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Carbon−Nitrogen Bond Formation Involving Well-Defined Aryl−Copper(III) Complexes

(2008) Lauren M. Huffman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dehydrogenation of Inert Alkyl Groups via Remote C−H Activation: Converting a Propyl Group into a π-Allylic Complex

(2008) Ramesh Giri et al.   ORGANOMETALLICS