Misfolding of Luciferase at the Single-Molecule Level

Chaperone Action at the Single-Molecule Level

(2013) Alireza Mashaghi et al.   CHEMICAL REVIEWS

Biophysical Characterization of Two Different Stable Misfolded Monomeric Polypeptides That Are Chaperone-Amenable Substrates

(2013) Antonino Natalello et al.   JOURNAL OF MOLECULAR BIOLOGY

Long-Loop G-Quadruplexes Are Misfolded Population Minorities with Fast Transition Kinetics in Human Telomeric Sequences

(2013) Deepak Koirala et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Reshaping of the conformational search of a protein by the chaperone trigger factor

(2013) Alireza Mashaghi et al.   NATURE

Single-molecule assays for investigating protein misfolding and aggregation

(2013) Armin Hoffmann et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

A Polypeptide-DNA Hybrid with Selective Linking Capability Applied to Single Molecule Nano-Mechanical Measurements Using Optical Tweezers

(2013) Fatemeh Moayed et al.   PLoS One

Single-molecule approaches to prion protein misfolding

(2013) Hao Yu et al.   Prion

Direct observation of multiple misfolding pathways in a single prion protein molecule

(2012) H. Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Energy landscape analysis of native folding of the prion protein yields the diffusion constant, transition path time, and rates

(2012) H. Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular chaperones in targeting misfolded proteins for ubiquitin-dependent degradation

(2011) Franziska Kriegenburg et al.   FEBS Journal

The Complex Folding Network of Single Calmodulin Molecules

(2011) J. Stigler et al.   SCIENCE

Induction of Molecular Chaperones as a Therapeutic Strategy for the Polyglutamine Diseases

(2010) Yoshitaka Nagai et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

The kinetic parameters and energy cost of the Hsp70 chaperone as a polypeptide unfoldase

(2010) Sandeep K Sharma et al.   Nature Chemical Biology

Structural characterization of a misfolded intermediate populated during the folding process of a PDZ domain

(2010) Stefano Gianni et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A Transient and Low-Populated Protein-Folding Intermediate at Atomic Resolution

(2010) Dmitry M. Korzhnev et al.   SCIENCE

Engineered Symmetric Connectivity of Secondary Structure Elements Highlights Malleability of Protein Folding Pathways

(2009) Ylva Ivarsson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The mechanism of folding of Im7 reveals competition between functional and kinetic evolutionary constraints

(2009) Claire T Friel et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The chaperonin TRiC blocks a huntingtin sequence element that promotes the conformational switch to aggregation

(2009) Stephen Tam et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Protein Misfolding in Conformational Disorders: Rescue of Folding Defects and Chemical Chaperoning

(2008) Paula Leandro et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Chaperonin chamber accelerates protein folding through passive action of preventing aggregation

(2008) A. C. Apetri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The folding pathway of an engineered circularly permuted PDZ domain

(2008) Y. Ivarsson et al.   PROTEIN ENGINEERING DESIGN & SELECTION