A Small-Molecule FRET Reporter for the Real-Time Visualization of Cell-Surface Proteolytic Enzyme Functions

In Vivo Imaging of Mouse Tumors by a Lipidated Cathepsin S Substrate

(2014) Hai-Yu Hu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Optical Image-Guided Cancer Therapy

(2014) Lihong Bu et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Toward a Chemical Marker for Inflammatory Disease: A Fluorescent Probe for Membrane-Localized Thioredoxin

(2014) Min Hee Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Small-Molecule-Based Protein-Labeling Technology in Live Cell Studies: Probe-Design Concepts and Applications

(2013) Shin Mizukami et al.   ACCOUNTS OF CHEMICAL RESEARCH

Activatable Oligomerizable Imaging Agents for Photoacoustic Imaging of Furin-Like Activity in Living Subjects

(2013) Anca Dragulescu-Andrasi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

High-Resolution Analysis and Functional Mapping of Cleavage Sites and Substrate Proteins of Furin in the Human Proteome

(2013) Sergey A. Shiryaev et al.   PLoS One

Intravital analysis of vascular permeability in mice using two-photon microscopy

(2013) Gyohei Egawa et al.   Scientific Reports

Monitoring β-Secretase Activity in Living Cells with a Membrane-Anchored FRET Probe

(2012) Drew S. Folk et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Spatially Resolved Monitoring of Neutrophil Elastase Activity with Ratiometric Fluorescent Reporters

(2012) Stefanie Gehrig et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Switchable Two-Photon Membrane Tracer Capable of Imaging Membrane-Associated Protein Tyrosine Phosphatase Activities

(2012) Lin Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The biology and therapeutic targeting of the proprotein convertases

(2012) Nabil G. Seidah et al.   NATURE REVIEWS DRUG DISCOVERY

A proprotein convertase/MMP-14 proteolytic cascade releases a novel 40 kDa vasculostatin from tumor suppressor BAI1

(2012) S M Cork et al.   ONCOGENE

Functional imaging of proteases: recent advances in the design and application of substrate-based and activity-based probes

(2011) Laura E Edgington et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

In Vivo Fluorescence Imaging of Bone-Resorbing Osteoclasts

(2011) Toshiyuki Kowada et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Principles for designing fluorescent sensors and reporters

(2011) Edward A Lemke et al.   Nature Chemical Biology

Activatable Photosensitizers for Imaging and Therapy

(2010) Jonathan F. Lovell et al.   CHEMICAL REVIEWS

Imaging proprotein convertase activities and their regulation in the implanting mouse blastocyst

(2010) Daniel Mesnard et al.   JOURNAL OF CELL BIOLOGY

Development and characterisation of an assay for furin activity

(2010) Gemma L. Bourne et al.   JOURNAL OF IMMUNOLOGICAL METHODS

A Femtomol Range FRET Biosensor Reports Exceedingly Low Levels of Cell Surface Furin: Implications for the Processing of Anthrax Protective Antigen

(2010) Katarzyna Gawlik et al.   PLoS One

Lipid Rafts As a Membrane-Organizing Principle

(2010) D. Lingwood et al.   SCIENCE

Two-Photon Absorption and the Design of Two-Photon Dyes

(2009) Miłosz Pawlicki et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tag–probe labeling methods for live-cell imaging of membrane proteins

(2009) Yoshiaki Yano et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

In Vivo Bioluminescence Imaging of Furin Activity in Breast Cancer Cells Using Bioluminogenic Substrates

(2009) Anca Dragulescu-Andrasi et al.   BIOCONJUGATE CHEMISTRY

Intramembrane Proteolysis

(2009) Michael S. Wolfe   CHEMICAL REVIEWS

Accumulation of FITC nearstratum corneum-visualizing epidermal distribution of a strong sensitizer using two-photon microscopy

(2009) Kristin Samuelsson et al.   CONTACT DERMATITIS

Inhibition of Furin/Proprotein Convertase-catalyzed Surface and Intracellular Processing by Small Molecules

(2009) Tomoko Komiyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Membrane-bound FRET probe visualizes MMP12 activity in pulmonary inflammation

(2009) Amanda Cobos-Correa et al.   Nature Chemical Biology

Activity-Based Protein Profiling: From Enzyme Chemistry to Proteomic Chemistry

(2008) Benjamin F. Cravatt et al.   Annual Review of Biochemistry

Two-Photon Fluorescent Probes for Biomembrane Imaging: Effect of Chain Length

(2008) Hwan Myung Kim et al.   CHEMBIOCHEM

Noncovalent Cell Surface Engineering: Incorporation of Bioactive Synthetic Glycopolymers into Cellular Membranes

(2008) David Rabuka et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Efficient Inhibition of the Alzheimer's Disease  -Secretase by Membrane Targeting

(2008) L. Rajendran et al.   SCIENCE