Organocatalytic Diastereo- and Enantioselective 1,3-Dipolar Cycloaddition of Azlactones and Methyleneindolinones

Recent Advances in Asymmetric Organocatalytic Construction of 3,3′-Spirocyclic Oxindoles

(2013) Liang Hong et al.   ADVANCED SYNTHESIS & CATALYSIS

An asymmetric approach toward chiral multicyclic spirooxindoles from isothiocyanato oxindoles and unsaturated pyrazolones by a chiral tertiary amine thiourea catalyst

(2013) Qiao Chen et al.   CHEMICAL COMMUNICATIONS

Highly stereoselective Michael addition of azlactones to electron-deficient triple bonds under P-spiro chiral iminophosphorane catalysis: importance of protonation pathway

(2013) Daisuke Uraguchi et al.   Chemical Science

Core Scaffold-Inspired Concise Synthesis of Chiral Spirooxindole-Pyranopyrimidines with Broad-Spectrum Anticancer Potency

(2012) Xianxing Jiang et al.   ADVANCED SYNTHESIS & CATALYSIS

A Chiral Bis(betaine) Catalyst for the Mannich Reaction of Azlactones and Aliphatic Imines

(2012) Wen-Quan Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic stereocontrolled synthesis of 3,3′-pyrrolidinyl spirooxindoles by [3+2] annulation of isocyanoesters with methyleneindolinones

(2012) Liang-Liang Wang et al.   CHEMICAL COMMUNICATIONS

Isatins As Privileged Molecules in Design and Synthesis of Spiro-Fused Cyclic Frameworks

(2012) Girija S. Singh et al.   CHEMICAL REVIEWS

Recent advances in organocatalytic methods for the synthesis of disubstituted 2- and 3-indolinones

(2012) Renato Dalpozzo et al.   CHEMICAL SOCIETY REVIEWS

Bispalladacycle-Catalyzed Michael Addition of In Situ Formed Azlactones to Enones

(2012) Manuel Weber et al.   CHEMISTRY-A EUROPEAN JOURNAL

An Organocatalytic Cascade Strategy for the Enantioselective Construction of Spirocyclopentane Bioxindoles Containing Three Contiguous Stereocenters and Two Spiro Quaternary Centers

(2012) Wangsheng Sun et al.   CHEMISTRY-A EUROPEAN JOURNAL

Scaffold-Inspired Enantioselective Synthesis of Biologically Important Spiro[pyrrolidin-3,2′-oxindoles] with Structural Diversity through Catalytic Isatin-Derived 1,3-Dipolar Cycloadditions

(2012) Feng Shi et al.   CHEMISTRY-A EUROPEAN JOURNAL

“Organo-Metal” Synergistic Catalysis: The 1+1>2 Effect for the Construction of Spirocyclopentene Oxindoles

(2012) Wangsheng Sun et al.   CHEMISTRY-A EUROPEAN JOURNAL

Catalytic Asymmetric Michael Addition/Cyclization of Isothiocyanato Oxindoles: Highly Efficient and Versatile Approach for the Synthesis of 3,2′-Pyrrolidinyl Mono- and Bi-spirooxindole Frameworks

(2012) Yi-Ming Cao et al.   CHEMISTRY-A EUROPEAN JOURNAL

Strategies for the enantioselective synthesis of spirooxindoles

(2012) Nicolas R. Ball-Jones et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synergistic Chiral Ion Pair Catalysts for Asymmetric Catalytic Synthesis of Quaternary α,β-Diamino Acids

(2012) Shi-Hui Shi et al.   ORGANIC LETTERS

Enantioselective Michael/Cyclization Reaction Sequence: Scaffold-Inspired Synthesis of Spirooxindoles with Multiple Stereocenters

(2011) Yiming Cao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Core Structure-Based Design of Organocatalytic [3+2]-Cycloaddition Reactions: Highly Efficient and Stereocontrolled Syntheses of 3,3′-Pyrrolidonyl Spirooxindoles

(2011) Bin Tan et al.   CHEMISTRY-A EUROPEAN JOURNAL

Highly Stereoselective [4+2] Cycloaddition of Azlactones to β,γ-Unsaturated α-Ketoesters Catalyzed by an Axially Chiral Guanidine Base

(2011) Masahiro Terada et al.   CHEMISTRY-A EUROPEAN JOURNAL

Oxazolones in Organocatalysis, New Tricks for an Old Reagent

(2011) Andrea-Nekane R. Alba et al.   Chemistry-An Asian Journal

A Dual-Catalysis Approach to the Asymmetric Steglich Rearrangement and Catalytic Enantioselective Addition ofO-Acylated Azlactones to Isoquinolines

(2011) Chandra Kanta De et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Gold(I)-Catalyzed Diastereo- and Enantioselective 1,3-Dipolar Cycloaddition and Mannich Reactions of Azlactones

(2011) Asa D. Melhado et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Aza-Mannich Addition: Synthesis of Modified Chiral 2-(Ethylthio)-thiazolone Derivatives with Anticancer Potency

(2011) Xiaodong Liu et al.   ORGANIC LETTERS

Asymmetric Synthesis of 3,4-Diaminochroman-2-ones Promoted by Guanidine and Bisguanidium Salt

(2011) Shunxi Dong et al.   ORGANIC LETTERS

Bifunctional cinchona alkaloids-catalyzed asymmetric [4+2] cycloaddition reaction of β,γ-unsaturated α-keto esters with oxazolones

(2011) Yin Ying et al.   TETRAHEDRON

Catalytic Asymmetric Synthesis of Oxindoles Bearing a Tetrasubstituted Stereocenter at the C-3 Position

(2010) Feng Zhou et al.   ADVANCED SYNTHESIS & CATALYSIS

Enantioselective Organocatalytic Addition of Azlactones to Maleimides: A Highly Stereocontrolled Entry to 2,2-Disubstituted-2H-oxazol-5-ones

(2010) Andrea-Nekane R. Alba et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis of 1,2,4-Triazolines and Triazoles Utilizing Oxazolones

(2010) Rahman Shah Zaib Saleem et al.   JOURNAL OF ORGANIC CHEMISTRY

Direct Asymmetric Aldol Reaction of 5H-Oxazol-4-ones with Aldehydes Catalyzed by Chiral Guanidines

(2010) Tomonori Misaki et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chiral Bisguanidine-Catalyzed Inverse-Electron-Demand Hetero-Diels−Alder Reaction of Chalcones with Azlactones

(2010) Shunxi Dong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Acyl Phosphonates: Good Hydrogen Bond Acceptors and Ester/Amide Equivalents in Asymmetric Organocatalysis

(2010) Hao Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Unique Approach to the Concise Synthesis of Highly Optically Active Spirooxazolines and the Discovery of a More Potent Oxindole-Type Phytoalexin Analogue

(2010) Xianxing Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly enantioselective synthesis and cellular evaluation of spirooxindoles inspired by natural products

(2010) Andrey P. Antonchick et al.   Nature Chemistry

Asymmetric Aza-Mannich Addition of Oxazolones toN-Tosyl Aldimines: Synthesis of Chiral α-Disubstituted α,β-Diamino Acids

(2010) Xiaodong Liu et al.   ORGANIC LETTERS

Isothiourea-Catalyzed Enantioselective Carboxy Group Transfer

(2009) Caroline Joannesse et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Flexible synthesis, structural determination, and synthetic application of a new C1-symmetric chiral ammonium betaine

(2009) Daisuke Uraguchi et al.   CHEMICAL COMMUNICATIONS

Asymmetric Synthesis of 3-Amino-δ-lactams and Benzo[a]quinolizidines by Catalytic Cyclization Reactions Involving Azlactones

(2009) Jun Jiang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantioselective Direct Aldol-Type Reaction of Azlactone via Protonation of Vinyl Ethers by a Chiral Brønsted Acid Catalyst

(2009) Masahiro Terada et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic Synthesis of Spiro[pyrrolidin-3,3′-oxindoles] with High Enantiopurity and Structural Diversity

(2009) Xiao-Hua Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chiral Organic Ion Pair Catalysts Assembled Through a Hydrogen-Bonding Network

(2009) D. Uraguchi et al.   SCIENCE

Asymmetric Syntheses of Oxindole and Indole Spirocyclic Alkaloid Natural Products

(2009) Barry Trost et al.   SYNTHESIS-STUTTGART

Stereoselective syntheses of quaternary substituted α-amino acids using oxazol-5-(4H)-ones

(2009) Robert A. Mosey et al.   TETRAHEDRON-ASYMMETRY

Site-Directed Asymmetric Quaternization of a Peptide Backbone at a C-Terminal Azlactone

(2008) Daisuke Uraguchi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Copper-Catalyzed 1,3-Dipolar Cycloadditions

(2008) Levi M. Stanley et al.   CHEMICAL REVIEWS

Asymmetric 1,4-Addition of Oxazolones to Nitroalkenes by Bifunctional Cinchona Alkaloid Thiourea Organocatalysts: Synthesis of α,α-Disubstituted α-Amino Acids

(2008) José Alemán et al.   CHEMISTRY-A EUROPEAN JOURNAL

Organocatalytic Asymmetric Synthesis of α,α-Disubstituted α-Amino Acids and Derivatives

(2008) Silvia Cabrera et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chiral Tetraaminophosphonium Carboxylate-Catalyzed Direct Mannich-Type Reaction

(2008) Daisuke Uraguchi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition

(2008) S. Shangary et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA