The Winding Pathway to Erythropoietin Along the Chemistry-Biology Frontier: A Success At Last

Peptide Ligation-Desulfurization Chemistry at Arginine

(2013) Lara R. Malins et al.   CHEMBIOCHEM

Chemistry as an Expanding Resource in Protein Science: Fully Synthetic and Fully Active Human Parathyroid Hormone-Related Protein (1-141)

(2012) Jianfeng Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Advance in the Chemical Synthesis of Homogeneous N-Linked Glycopolypeptides by Convergent Aspartylation

(2012) Ping Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Convergent Solid-Phase Synthesis of N-Glycopeptides Facilitated by Pseudoprolines at Consensus-Sequence Ser/Thr Residues

(2012) Vera Ullmann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemical Synthesis of an Erythropoietin Glycoform Containing a Complex-type Disialyloligosaccharide

(2012) Masumi Murakami et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

At Last: Erythropoietin as a Single Glycoform

(2012) Ping Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total Synthesis of Homogeneous Antifreeze Glycopeptides and Glycoproteins

(2012) Brendan L. Wilkinson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Sequential native peptide ligation strategies for total chemical protein synthesis

(2012) Laurent Raibaut et al.   CHEMICAL SOCIETY REVIEWS

Engineering of Therapeutic Polypeptides through Chemical Synthesis: Early Lessons from Human Parathyroid Hormone and Analogues

(2012) Suwei Dong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Synthesis of the α-Subunit of Human Glycoprotein Hormones: Toward Fully Synthetic Homogeneous Human Follicle-Stimulating Hormone

(2012) Baptiste Aussedat et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chemical Synthesis of Homogeneous Human Glycosyl-interferon-β That Exhibits Potent Antitumor Activity in Vivo

(2012) Izumi Sakamoto et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stability of Nucleosomes Containing Homogenously Ubiquitylated H2A and H2B Prepared Using Semisynthesis

(2012) Beat Fierz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Native Chemical Ligation at Glutamine

(2012) Peter Siman et al.   ORGANIC LETTERS

Probing the stability of nonglycosylated wild-type erythropoietin protein via reiterative alanine ligations

(2012) J. A. Brailsford et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chemical Synthesis of Ubiquitinated Peptides with Varying Lengths and Types of Ubiquitin Chains to Explore the Activity of Deubiquitinases

(2011) Sudhir N. Bavikar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Convergent Chemical Synthesis of [Lysine24, 38, 83] Human Erythropoietin

(2011) Suhuai Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Probing the Frontiers of Glycoprotein Synthesis: The Fully Elaborated β-Subunit of the Human Follicle-Stimulating Hormone

(2011) Pavel Nagorny et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Toward Homogeneous Erythropoietin: Application of Metal-Free Dethiylation in the Chemical Synthesis of the Ala79-Arg166 Glycopeptide Domain

(2011) Suwei Dong et al.   ISRAEL JOURNAL OF CHEMISTRY

An Advance in Proline Ligation

(2011) Shiying Shang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rational development of a strategy for modifying the aggregatibility of proteins

(2011) Z. Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insights into the Finer Issues of Native Chemical Ligation: An Approach to Cascade Ligations

(2010) Zhongping Tan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The role of erythropoietin and its receptor in growth, survival and therapeutic response of human tumor cells

(2010) Jolanta Szenajch et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Protein Synthesis Assisted by Native Chemical Ligation at Leucine

(2010) Ziv Harpaz et al.   CHEMBIOCHEM

A program for ligation at threonine sites: application to the controlled total synthesis of glycopeptides

(2010) Jin Chen et al.   TETRAHEDRON

Highly Efficient and Chemoselective Peptide Ubiquitylation

(2009) K. S. Ajish Kumar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Semisynthesis of a Homogeneous Glycoprotein Enzyme: Ribonuclease C: Part 1

(2009) Christian Piontek et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Semisynthesis of a Homogeneous Glycoprotein Enzyme: Ribonuclease C: Part 2

(2009) Christian Piontek et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Design and Synthesis of a Homogeneous Erythropoietin Analogue with Two Human Complex-Type Sialyloligosaccharides: Combined Use of Chemical and Bacterial Protein Expression Methods

(2009) Kiriko Hirano et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Toward Homogeneous Erythropoietin: Chemical Synthesis of the Ala1−Gly28Glycopeptide Domain by “Alanine” Ligation

(2009) Cindy Kan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Toward Homogeneous Erythropoietin: Fine Tuning of the C-Terminal Acyl Donor in the Chemical Synthesis of the Cys29−Gly77Glycopeptide Domain

(2009) Yu Yuan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Toward Homogeneous Erythropoietin: Non-NCL-Based Chemical Synthesis of the Gln78−Arg166Glycopeptide Domain

(2009) Zhongping Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dual Native Chemical Ligation at Lysine

(2009) Renliang Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recent departures in the synthesis of peptides and glycopeptides

(2009) Cindy Kan et al.   TETRAHEDRON

Native Chemical Ligation at Valine: A Contribution to Peptide and Glycopeptide Synthesis

(2008) Jin Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Native Chemical Ligation at Valine

(2008) Christian Haase et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Optimisation of chemical protein cleavage for erythropoietin semi-synthesis using native chemical ligation

(2008) Jonathan P. Richardson et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Therapeutic effect against human xenograft tumors in nude mice by the third generation microtubule stabilizing epothilones

(2008) T.-C. Chou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chemical Synthesis of a Glycoprotein Having an Intact Human Complex-Type Sialyloligosaccharide under the Boc and Fmoc Synthetic Strategies

(2007) Naoki Yamamoto et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY