Chemistry as an Expanding Resource in Protein Science: Fully Synthetic and Fully Active Human Parathyroid Hormone-Related Protein (1-141)

Engineering of Therapeutic Polypeptides through Chemical Synthesis: Early Lessons from Human Parathyroid Hormone and Analogues

(2012) Suwei Dong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Luminescent Biosensor with Increased Dynamic Range for Intracellular cAMP

(2011) Brock F. Binkowski et al.   ACS Chemical Biology

Combinatorial library discovery of small molecule inhibitors of lung cancer proliferation and parathyroid hormone-related protein expression

(2011) Randolph H. Hastings et al.   CANCER BIOLOGY & THERAPY

PTHrP stimulates prostate cancer cell growth and upregulates aldo–keto reductase 1C3

(2011) Tracy M. Downs et al.   CANCER LETTERS

PTHrP drives breast tumor initiation, progression, and metastasis in mice and is a potential therapy target

(2011) Jiarong Li et al.   JOURNAL OF CLINICAL INVESTIGATION

An Advance in Proline Ligation

(2011) Shiying Shang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

TAK1-TAB2 Signaling Contributes to Bone Destruction by Breast Carcinoma Cells

(2011) A. Safina et al.   MOLECULAR CANCER RESEARCH

Application of the logic of cysteine-free native chemical ligation to the synthesis of Human Parathyroid Hormone (hPTH)

(2011) S. Shang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insights into the Finer Issues of Native Chemical Ligation: An Approach to Cascade Ligations

(2010) Zhongping Tan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Adding New Chemistries to the Genetic Code

(2010) Chang C. Liu et al.   Annual Review of Biochemistry

Parathyroid Hormone-Related Protein for the Treatment of Postmenopausal Osteoporosis: Defining the Maximal Tolerable Dose

(2010) Mara J. Horwitz et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

A program for ligation at threonine sites: application to the controlled total synthesis of glycopeptides

(2010) Jin Chen et al.   TETRAHEDRON

Structural Basis for Parathyroid Hormone-related Protein Binding to the Parathyroid Hormone Receptor and Design of Conformation-selective Peptides

(2009) Augen A. Pioszak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Native Chemical Ligation at Valine: A Contribution to Peptide and Glycopeptide Synthesis

(2008) Jin Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Native Chemical Ligation at Valine

(2008) Christian Haase et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total chemical synthesis of proteins

(2008) Stephen B. H. Kent   CHEMICAL SOCIETY REVIEWS

PTHrP promotes homotypic aggregation of breast cancer cells in three-dimensional cultures

(2007) Angela Dittmer et al.   CANCER LETTERS

Altered Selectivity of Parathyroid Hormone (PTH) and PTH-Related Protein (PTHrP) for Distinct Conformations of the PTH/PTHrP Receptor

(2007) Thomas Dean et al.   MOLECULAR ENDOCRINOLOGY