Chemical Synthesis of Ubiquitinated Peptides with Varying Lengths and Types of Ubiquitin Chains to Explore the Activity of Deubiquitinases

Total Chemical Synthesis of a 304 Amino Acid K48-Linked Tetraubiquitin Protein

(2011) K. S. Ajish Kumar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Expanded Click Conjugation of Recombinant Proteins with Ubiquitin-Like Modifiers Reveals Altered Substrate Preference of SUMO2-Modified Ubc9

(2011) Stefanie Sommer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Expeditious Chemical Synthesis of Ubiquitinated Peptides Employing Orthogonal Protection and Native Chemical Ligation

(2011) K. S. Ajish Kumar et al.   BIOCONJUGATE CHEMISTRY

Controlled enzymatic synthesis of natural-linkage, defined-length polyubiquitin chains using lysines with removable protecting groups

(2011) Carlos A. Castañeda et al.   CHEMICAL COMMUNICATIONS

Traceless and Site-Specific Ubiquitination of Recombinant Proteins

(2011) Satpal Virdee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Towards Elucidation of the Role of Ubiquitination in the Pathogenesis of Parkinson’s Disease with Semisynthetic Ubiquitinated α-Synuclein

(2010) Mirva Hejjaoui et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total Chemical Synthesis of Di-ubiquitin Chains

(2010) K. S. Ajish Kumar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Carpe Diubiquitin

(2010) Langdon J. Martin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemical Synthesis of Ubiquitin, Ubiquitin-Based Probes, and Diubiquitin

(2010) Farid El Oualid et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Protecting group variations of δ-mercaptolysine useful in chemical ubiquitylation

(2010) Mahmood Haj-Yahya et al.   BIOPOLYMERS

Biological Applications of Protein Splicing

(2010) Miquel Vila-Perelló et al.   CELL

Generation of Site-Specific and Enzymatically Stable Conjugates of Recombinant Proteins with Ubiquitin-Like Modifiers by the CuI-Catalyzed Azide-Alkyne Cycloaddition

(2010) Nadine D. Weikart et al.   CHEMBIOCHEM

Nonenzymatic Ubiquitylation

(2010) Tomasz Fekner et al.   CHEMBIOCHEM

Synthesis of K48-linked diubiquitin using dual native chemical ligation at lysine

(2010) Renliang Yang et al.   CHEMICAL COMMUNICATIONS

Nonhydrolyzable Ubiquitin−Isopeptide Isosteres as Deubiquitinating Enzyme Probes.

(2010) Anitha Shanmugham et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of Defined Ubiquitin Dimers

(2010) Silvia Eger et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chemically ubiquitylated PCNA as a probe for eukaryotic translesion DNA synthesis

(2010) Junjun Chen et al.   Nature Chemical Biology

Engineered diubiquitin synthesis reveals Lys29-isopeptide specificity of an OTU deubiquitinase

(2010) Satpal Virdee et al.   Nature Chemical Biology

Disulfide-directed histone ubiquitylation reveals plasticity in hDot1L activation

(2010) Champak Chatterjee et al.   Nature Chemical Biology

N-Methylcysteine-mediated total chemical synthesis of ubiquitin thioester

(2010) Lesly A. Erlich et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Highly Efficient and Chemoselective Peptide Ubiquitylation

(2009) K. S. Ajish Kumar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Pyrrolysine Analogue for Site-Specific Protein Ubiquitination

(2009) Xin Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Functional Ubiquitin Conjugates with Lysine-ε-Amino-Specific Linkage by Thioether Ligation of Cysteinyl-Ubiquitin Peptide Building Blocks

(2009) Ji Eun Jung et al.   BIOCONJUGATE CHEMISTRY

Polyubiquitin Binding and Disassembly By Deubiquitinating Enzymes

(2009) Francisca E. Reyes-Turcu et al.   CHEMICAL REVIEWS

Dual Native Chemical Ligation at Lysine

(2009) Renliang Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Modification by Single Ubiquitin Moieties Rather Than Polyubiquitination Is Sufficient for Proteasomal Processing of the p105 NF-κB Precursor

(2009) Yelena Kravtsova-Ivantsiv et al.   MOLECULAR CELL

Native Chemical Ligation at Valine

(2008) Christian Haase et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Atypical ubiquitin chains: new molecular signals. ‘Protein Modifications: Beyond the Usual Suspects’ Review Series

(2008) Fumiyo Ikeda et al.   EMBO REPORTS

Substrate Filtering by the Active Site Crossover Loop in UCHL3 Revealed by Sortagging and Gain-of-function Mutations

(2008) Maximilian W. Popp et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chemically ubiquitylated histone H2B stimulates hDot1L-mediated intranucleosomal methylation

(2008) Robert K. McGinty et al.   NATURE