Omuralide and Vibralactone: Differences in the Proteasome- β-Lactone-γ-Lactam Binding Scaffold Alter Target Preferences

Synthesis and Pharmacology of Proteasome Inhibitors

(2013) Andreas Rentsch et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Inhibitors for the Immuno- and Constitutive Proteasome: Current and Future Trends in Drug Development

(2012) Eva Maria Huber et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Covalent and non-covalent reversible proteasome inhibition

(2012) Philipp Beck et al.   BIOLOGICAL CHEMISTRY

Immuno- and Constitutive Proteasome Crystal Structures Reveal Differences in Substrate and Inhibitor Specificity

(2012) Eva M. Huber et al.   CELL

One-shot NMR analysis of microbial secretions identifies highly potent proteasome inhibitor

(2012) M. L. Stein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of Acyl Protein Thioesterases 1 and 2 as the Cellular Targets of the Ras-Signaling Modulators Palmostatin B and M

(2011) Marion Rusch et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Vibralactone as a Tool to Study the Activity and Structure of the ClpP1P2 Complex from Listeria monocytogenes

(2011) Evelyn Zeiler et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Exploiting nature's rich source of proteasome inhibitors as starting points in drug development

(2011) Melissa Ann Gräwert et al.   CHEMICAL COMMUNICATIONS

Proteasome Structure, Function, and Lessons Learned from Beta-Lactone Inhibitors

(2011) Michael Groll et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Natural Products and Their Biological Targets: Proteomic and Metabolomic Labeling Strategies

(2010) Thomas Böttcher et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Salinosporamide Natural Products: Potent 20 S Proteasome Inhibitors as Promising Cancer Chemotherapeutics

(2010) Tobias A. M. Gulder et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Strategies for discovering and derisking covalent, irreversible enzyme inhibitors

(2010) Douglas S Johnson et al.   Future Medicinal Chemistry

Peripheral neuropathy during bortezomib treatment of multiple myeloma: a review of recent studies

(2010) Guido Cavaletti et al.   LEUKEMIA & LYMPHOMA

Small-molecule inhibition of APT1 affects Ras localization and signaling

(2010) Frank J Dekker et al.   Nature Chemical Biology

Reversibility of symptomatic peripheral neuropathy with bortezomib in the phase III APEX trial in relapsed multiple myeloma: impact of a dose-modification guideline

(2009) Paul G. Richardson et al.   BRITISH JOURNAL OF HAEMATOLOGY

Activity-based probes as a tool for functional proteomic analysis of proteases

(2008) Marko Fonović et al.   Expert Review of Proteomics