Salinosporamide Natural Products: Potent 20 S Proteasome Inhibitors as Promising Cancer Chemotherapeutics
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Title
Salinosporamide Natural Products: Potent 20 S Proteasome Inhibitors as Promising Cancer Chemotherapeutics
Authors
Keywords
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Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 49, Issue 49, Pages 9346-9367
Publisher
Wiley
Online
2010-10-07
DOI
10.1002/anie.201000728
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Note: Only part of the references are listed.- Inhibition of Yin Yang 1-Dependent Repressor Activity of DR5 Transcription and Expression by the Novel Proteasome Inhibitor NPI-0052 Contributes to its TRAIL-Enhanced Apoptosis in Cancer Cells
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- (2010) Ajita V. Singh et al. BRITISH JOURNAL OF HAEMATOLOGY
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- (2010) Henry Nguyen et al. CHEMICAL COMMUNICATIONS
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- (2010) Alessandra S. Eustáquio et al. JOURNAL OF NATURAL PRODUCTS
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- (2009) Christian Bailly BIOCHEMICAL PHARMACOLOGY
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- (2009) D. Chauhan et al. BLOOD
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- (2009) S. Baritaki et al. CANCER RESEARCH
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- (2009) Gordon M. Cragg et al. CHEMICAL REVIEWS
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- Chasing the treasures of the sea—bacterial marine natural products
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- Different roads to discovery; Prontosil (hence sulfa drugs) and penicillin (hence β-lactams)
- (2009) Ronald Bentley JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
- Snapshots of the Fluorosalinosporamide/20S Complex Offer Mechanistic Insights for Fine Tuning Proteasome Inhibition
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- Antiprotealide Is a Natural Product
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- Development of Yondelis® (trabectedin, ET-743). A semisynthetic process solves the supply problem
- (2009) Carmen Cuevas et al. NATURAL PRODUCT REPORTS
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- (2009) Gang Lin et al. NATURE
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- (2009) S Baritaki et al. ONCOGENE
- Natural compounds for cancer treatment and prevention
- (2009) Stefania Nobili et al. PHARMACOLOGICAL RESEARCH
- Nature: a vital source of leads for anticancer drug development
- (2009) G. M. Cragg et al. PHYTOCHEMISTRY REVIEWS
- Biosynthesis of the salinosporamide A polyketide synthase substrate chloroethylmalonyl-coenzyme A from S-adenosyl-L-methionine
- (2009) A. S. Eustaquio et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Carboxylation mechanism and stereochemistry of crotonyl-CoA carboxylase/reductase, a carboxylating enoyl-thioester reductase
- (2009) T. J. Erb et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- A concise and straightforward total synthesis of (±)-salinosporamide A, based on a biosynthesis model
- (2008) Nicholas P Mulholland et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Total Synthesis of Salinosporamide A
- (2008) Takeo Fukuda et al. ORGANIC LETTERS
- Marine Actinomycetes: A New Source of Compounds against the Human Malaria Parasite
- (2008) Jacques Prudhomme et al. PLoS One
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- (2008) Isabel Villanueva Margalef et al. TETRAHEDRON
- New synthetic route to access (±) salinosporamide A via an oxazolone-mediated ene-type reaction
- (2008) Robert A. Mosey et al. TETRAHEDRON LETTERS
- Panning for chemical gold: marine bacteria as a source of new therapeutics
- (2008) Philip G. Williams TRENDS IN BIOTECHNOLOGY
- Proteasome inhibitors: Poisons and remedies
- (2007) Silke Meiners et al. MEDICINAL RESEARCH REVIEWS
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