Vibralactone as a Tool to Study the Activity and Structure of the ClpP1P2 Complex from Listeria monocytogenes

A Conformational Switch Underlies ClpP Protease Function

(2011) Sebastian R. Geiger et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Natural Products and Their Biological Targets: Proteomic and Metabolomic Labeling Strategies

(2010) Thomas Böttcher et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Click-based synthesis and proteomic profiling of lipstatin analogues

(2010) Mun H. Ngai et al.   CHEMICAL COMMUNICATIONS

Strategies for discovering and derisking covalent, irreversible enzyme inhibitors

(2010) Douglas S Johnson et al.   Future Medicinal Chemistry

β-Lactones Decrease the Intracellular Virulence ofListeria monocytogenesin Macrophages

(2009) Thomas Böttcher et al.   ChemMedChem

Structure and Function of a Novel Type of ATP-dependent Clp Protease

(2009) Fredrik I. Andersson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activity-Based Proteome Profiling of Potential Cellular Targets of Orlistat − An FDA-Approved Drug with Anti-Tumor Activities

(2009) Peng-Yu Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Optimal Efficiency of ClpAP and ClpXP Chaperone-Proteases Is Achieved by Architectural Symmetry

(2009) Željka Maglica et al.   STRUCTURE

β-Lactones as Privileged Structures for the Active-Site Labeling of Versatile Bacterial Enzyme Classes

(2008) Thomas Böttcher et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Activity-based probes as a tool for functional proteomic analysis of proteases

(2008) Marko Fonović et al.   Expert Review of Proteomics

β-Lactones as Specific Inhibitors of ClpP Attenuate the Production of Extracellular Virulence Factors ofStaphylococcus aureus

(2008) Thomas Böttcher et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

β-Lactone probes identify a papain-like peptide ligase in Arabidopsis thaliana

(2008) Zheming Wang et al.   Nature Chemical Biology

Synthesis of (±)-Vibralactone

(2008) Quan Zhou et al.   ORGANIC LETTERS