Overcoming the Limitations of Lithiation Chemistry for Organoboron Compounds with Continuous Processing

Synthesis of Phenylboronic Acids in Continuous Flow by Means of a Multijet Oscillating Disc Reactor System Operating at Cryogenic Temperatures

(2012) Dagfinn Sleveland et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Convergent, Kilogram Scale Synthesis of an Akt Kinase Inhibitor

(2012) Pintipa Grongsaard et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Continuous-Flow Synthesis of Biaryls Enabled by Multistep Solid-Handling in a Lithiation/Borylation/Suzuki-Miyaura Cross-Coupling Sequence

(2011) Wei Shu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cross-Coupling Reactions Of Organoboranes: An Easy Way To Construct CC Bonds (Nobel Lecture)

(2011) Akira Suzuki   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Large-Scale Applications of Transition Metal-Catalyzed Couplings for the Synthesis of Pharmaceuticals

(2011) Javier Magano et al.   CHEMICAL REVIEWS

Flow microreactor synthesis of disubstituted pyridines from dibromopyridines via Br/Li exchange without using cryogenic conditions

(2011) Aiichiro Nagaki et al.   GREEN CHEMISTRY

Highly Efficient One-Pot Access to Functionalized Arylboronic Acids via Noncryogenic Bromine/Magnesium Exchanges

(2011) Timo Leermann et al.   ORGANIC LETTERS

A New Enabling Technology for Convenient Laboratory Scale Continuous Flow Processing at Low Temperatures

(2011) Duncan L. Browne et al.   ORGANIC LETTERS

Noncryogenic Preparation of Functionalized Arylboronic Esters through a Magnesium−Iodine Exchange with in Situ Quench

(2011) Emilien Demory et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Cross-Coupling in a Flow Microreactor: Space Integration of Lithiation and Murahashi Coupling

(2010) Aiichiro Nagaki et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total Synthesis of (+)-Korupensamine B via an Atropselective Intermolecular Biaryl Coupling

(2010) Shenlin Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed, Direct Boronic Acid Synthesis from Aryl Chlorides: A Simplified Route to Diverse Boronate Ester Derivatives

(2010) Gary A. Molander et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

C−H Activation for the Construction of C−B Bonds

(2009) Ibraheem A. I. Mkhalid et al.   CHEMICAL REVIEWS

Trifluoromethyl-substituted pyridyl- and pyrazolylboronic acids and esters: synthesis and Suzuki–Miyaura cross-coupling reactions

(2009) Kate M. Clapham et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Chemical Development of NBI-75043. Use of a Flow Reactor to Circumvent a Batch-Limited Metal−Halogen Exchange Reaction

(2008) Timothy D. Gross et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT