Continuous-Flow Synthesis of Biaryls Enabled by Multistep Solid-Handling in a Lithiation/Borylation/Suzuki-Miyaura Cross-Coupling Sequence

Practical One-Pot Preparation of Magnesium Di(hetero)aryl- and Magnesium Dialkenylboronates for Suzuki-Miyaura Cross-Coupling Reactions

(2011) Benjamin A. Haag et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

One-Flow, Multistep Synthesis of Nucleosides by Brønsted Acid-Catalyzed Glycosylation

(2011) Adam Sniady et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Suzuki-Miyaura Cross-Coupling Reactions in Flow: Multistep Synthesis Enabled by a Microfluidic Extraction

(2011) Timothy Noël et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ten key issues in modern flow chemistry

(2011) Jens Wegner et al.   CHEMICAL COMMUNICATIONS

Recent advances in micro reaction technology

(2011) Charlotte Wiles et al.   CHEMICAL COMMUNICATIONS

A Teflon microreactor with integrated piezoelectric actuator to handle solid forming reactions

(2011) Simon Kuhn et al.   LAB ON A CHIP

A New Enabling Technology for Convenient Laboratory Scale Continuous Flow Processing at Low Temperatures

(2011) Duncan L. Browne et al.   ORGANIC LETTERS

Cross-Coupling in a Flow Microreactor: Space Integration of Lithiation and Murahashi Coupling

(2010) Aiichiro Nagaki et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A flow-based synthesis of Imatinib: the API of Gleevec

(2010) Mark D. Hopkin et al.   CHEMICAL COMMUNICATIONS

Heterogeneous catalytic synthesis using microreactor technology

(2010) Christopher G. Frost et al.   GREEN CHEMISTRY

Palladium-Catalyzed, Direct Boronic Acid Synthesis from Aryl Chlorides: A Simplified Route to Diverse Boronate Ester Derivatives

(2010) Gary A. Molander et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A New Palladium Precatalyst Allows for the Fast Suzuki−Miyaura Coupling Reactions of Unstable Polyfluorophenyl and 2-Heteroaryl Boronic Acids

(2010) Tom Kinzel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Preparation of arylsulfonyl chlorides by chlorosulfonylation of in situ generated diazonium salts using a continuous flow reactor

(2010) Laia Malet-Sanz et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

KMnO4-Mediated Oxidation as a Continuous Flow Process

(2010) Jörg Sedelmeier et al.   ORGANIC LETTERS

Photodimerization of Maleic Anhydride in a Microreactor Without Clogging

(2010) Tomoaki Horie et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Overcoming the Challenges of Solid Bridging and Constriction during Pd-Catalyzed C−N Bond Formation in Microreactors

(2010) Ryan L. Hartman et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Continuous flow multi-step organic synthesis

(2010) Damien Webb et al.   Chemical Science

Palladium-catalyzed amination reactions in flow: overcoming the challenges of clogging via acoustic irradiation

(2010) Timothy Noël et al.   Chemical Science

Multistep Synthesis Using Modular Flow Reactors: Bestmann-Ohira Reagent for the Formation of Alkynes and Triazoles

(2009) Ian R. Baxendale et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Continuous-Flow Synthesis of Ibuprofen

(2009) Andrew R. Bogdan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pd-PEPPSI-IPent: An Active, Sterically Demanding Cross-Coupling Catalyst and Its Application in the Synthesis of Tetra-Ortho-Substituted Biaryls

(2009) Michael G. Organ et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

C−H Activation for the Construction of C−B Bonds

(2009) Ibraheem A. I. Mkhalid et al.   CHEMICAL REVIEWS

Sterically demanding trialkylphosphines for palladium-catalyzed cross coupling reactions—alternatives to PtBu3

(2009) Christoph A. Fleckenstein et al.   CHEMICAL SOCIETY REVIEWS

Synthesis of Original 2-Substituted 4-Arylquinazolines by Microwave-Irradiated Suzuki-Miyaura Cross-Coupling Reactions

(2009) Youssef Kabri et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Combined Directedorthoand Remote Metalation−Suzuki Cross-Coupling Strategies. Efficient Synthesis of Heteroaryl-Fused Benzopyranones from BiarylO-Carbamates

(2009) Clint A. James et al.   JOURNAL OF ORGANIC CHEMISTRY

Microchemical systems for continuous-flow synthesis

(2009) Ryan L. Hartman et al.   LAB ON A CHIP

A Multistep Continuous-Flow System for Rapid On-Demand Synthesis of Receptor Ligands

(2009) Trine P. Petersen et al.   ORGANIC LETTERS

Palladium-Catalyzed Suzuki−Miyaura Cross-Coupling Reactions Employing Dialkylbiaryl Phosphine Ligands

(2008) Ruben Martin et al.   ACCOUNTS OF CHEMICAL RESEARCH

Trimethylaluminium mediated amide bond formation in a continuous flow microreactor as key to the synthesis of rimonabant and efaproxiral

(2008) Tomas Gustafsson et al.   CHEMICAL COMMUNICATIONS

Flash Chemistry: Fast Chemical Synthesis by Using Microreactors

(2008) Jun-ichi Yoshida et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Bifurcated Pathway to Thiazoles and Imidazoles Using a Modular Flow Microreactor

(2008) Ian R. Baxendale et al.   JOURNAL OF COMBINATORIAL CHEMISTRY

An Efficient Synthesis and Substitution of 3-Aroyl-2-bromobenzo[b]furans

(2008) Gurmit S. Gill et al.   JOURNAL OF ORGANIC CHEMISTRY

Rapid Multistep Synthesis of 1,2,4-Oxadiazoles in a Single Continuous Microreactor Sequence

(2008) Daniel Grant et al.   JOURNAL OF ORGANIC CHEMISTRY

An Improved System for the Palladium-Catalyzed Borylation of Aryl Halides with Pinacol Borane

(2008) Kelvin L. Billingsley et al.   JOURNAL OF ORGANIC CHEMISTRY

A modular flow reactor for performing Curtius rearrangements as a continuous flow process

(2008) Marcus Baumann et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Azide monoliths as convenient flow reactors for efficient Curtius rearrangement reactions

(2008) Marcus Baumann et al.   ORGANIC & BIOMOLECULAR CHEMISTRY