Integration of Autophagy and Anoikis Resistance in Solid Tumors

Detachment-induced autophagy duringanoikisand lumen formation in epithelial acini

(2014) Jayanta Debnath   Autophagy

Curbing autophagy and histone deacetylases to kill cancer cells

(2012) Noor Gammoh et al.   Autophagy

Hypoxia-Induced Autophagy Promotes Tumor Cell Survival and Adaptation to Antiangiogenic Treatment in Glioblastoma

(2012) Y.-L. Hu et al.   CANCER RESEARCH

Tumor Cell Autophagy as an Adaptive Response Mediating Resistance to Treatments Such as Antiangiogenic Therapy

(2012) Y.-L. Hu et al.   CANCER RESEARCH

ROCK1 and ROCK2 Are Required for Non-Small Cell Lung Cancer Anchorage-Independent Growth and Invasion

(2012) D. Vigil et al.   CANCER RESEARCH

Integrin-linked kinase as a target for ERG-mediated invasive properties in prostate cancer models

(2012) D. D. Becker-Santos et al.   CARCINOGENESIS

Impairment of lysosomal integrity by B10, a glycosylated derivative of betulinic acid, leads to lysosomal cell death and converts autophagy into a detrimental process

(2012) P Gonzalez et al.   CELL DEATH AND DIFFERENTIATION

Relationship between growth arrest and autophagy in midgut programmed cell death in Drosophila

(2012) D Denton et al.   CELL DEATH AND DIFFERENTIATION

Molecules and their functions in autophagy

(2012) Jong-Ok Pyo et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Histone deacetylase 6 functions as a tumor suppressor by activating c-Jun NH2-terminal kinase-mediated beclin 1-dependent autophagic cell death in liver cancer

(2012) Kwang Hwa Jung et al.   HEPATOLOGY

Heme Oxygenase-1 Promotes Survival of Renal Cancer Cells through Modulation of Apoptosis- and Autophagy-regulating Molecules

(2012) Pallavi Banerjee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rad9 Protein Contributes to Prostate Tumor Progression by Promoting Cell Migration and Anoikis Resistance

(2012) Constantinos G. Broustas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy Inhibitor Chloroquine Enhanced the Cell Death Inducing Effect of the Flavonoid Luteolin in Metastatic Squamous Cell Carcinoma Cells

(2012) Lien Verschooten et al.   PLoS One

Atg7 Modulates p53 Activity to Regulate Cell Cycle and Survival During Metabolic Stress

(2012) I. H. Lee et al.   SCIENCE

Akt-Mediated Regulation of Autophagy and Tumorigenesis Through Beclin 1 Phosphorylation

(2012) R. C. Wang et al.   SCIENCE

Study on the Autophagy of Prostate Cancer PC-3 Cells Induced by Oridonin

(2011) Li-Hong Ye et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Autophagic cell death: Loch Ness monster or endangered species?

(2011) Han-Ming Shen et al.   Autophagy

Re-expression of ARHI (DIRAS3) induces autophagy in breast cancer cells and enhances the inhibitory effect of paclitaxel

(2011) Chun-Fang Zou et al.   BMC CANCER

Lysosomal Transmembrane Protein LAPTM4B Promotes Autophagy and Tolerance to Metabolic Stress in Cancer Cells

(2011) Y. Li et al.   CANCER RESEARCH

Autophagy: for better or for worse

(2011) Ellen Wirawan et al.   CELL RESEARCH

microRNA-214 contributes to melanoma tumour progression through suppression of TFAP2C

(2011) Elisa Penna et al.   EMBO JOURNAL

Inhibition of autophagy may suppress the development of hepatoblastoma

(2011) Yanxin Chang et al.   FEBS Journal

Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma

(2011) Satoshi Shimizu et al.   INTERNATIONAL JOURNAL OF CANCER

BCL-2 Modifying Factor (BMF) Is a Central Regulator of Anoikis in Human Intestinal Epithelial Cells

(2011) Martin Hausmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Overcoming anoikis - pathways to anchorage-independent growth in cancer

(2011) M. C. Guadamillas et al.   JOURNAL OF CELL SCIENCE

Anoikis: an emerging hallmark in health and diseases

(2011) ML Taddei et al.   JOURNAL OF PATHOLOGY

WZ4002, a third-generation EGFR inhibitor, can overcome anoikis resistance in EGFR-mutant lung adenocarcinomas more efficiently than Src inhibitors

(2011) Yuji Sakuma et al.   LABORATORY INVESTIGATION

A Pathway for the Control of Anoikis Sensitivity by E-Cadherin and Epithelial-to-Mesenchymal Transition

(2011) S. Kumar et al.   MOLECULAR AND CELLULAR BIOLOGY

PERK Integrates Autophagy and Oxidative Stress Responses To Promote Survival during Extracellular Matrix Detachment

(2011) A. Avivar-Valderas et al.   MOLECULAR AND CELLULAR BIOLOGY

The Role of Autophagy in Cancer: Therapeutic Implications

(2011) Z. J. Yang et al.   MOLECULAR CANCER THERAPEUTICS

Oncogenic Ras-Induced Expression of Noxa and Beclin-1 Promotes Autophagic Cell Death and Limits Clonogenic Survival

(2011) Mohamed Elgendy et al.   MOLECULAR CELL

DEPTOR, an mTOR Inhibitor, Is a Physiological Substrate of SCFβTrCP E3 Ubiquitin Ligase and Regulates Survival and Autophagy

(2011) Yongchao Zhao et al.   MOLECULAR CELL

Combination of N-(4-hydroxyphenyl) retinamide and apigenin suppressed starvation-induced autophagy and promoted apoptosis in malignant neuroblastoma cells

(2011) Nishant Mohan et al.   NEUROSCIENCE LETTERS

Zeb1 is required for TrkB-induced epithelial-mesenchymal transition, anoikis resistance and metastasis

(2011) M A Smit et al.   ONCOGENE

Nutrient starvation elicits an acute autophagic response mediated by Ulk1 dephosphorylation and its subsequent dissociation from AMPK

(2011) L. Shang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Live Free or Die

(2010) Craig Horbinski et al.   AMERICAN JOURNAL OF PATHOLOGY

Curcumin sensitizes non-small cell lung cancer cell anoikis through reactive oxygen species-mediated Bcl-2 downregulation

(2010) Varisa Pongrakhananon et al.   APOPTOSIS

Autophagy potentiates the anti-cancer effects of the histone deacetylase inhibitors in hepatocellular carcinoma

(2010) Yuan-Ling Liu et al.   Autophagy

Autophagy inhibition enhances apoptosis triggered by BO-1051, an N-mustard derivative, and involves the ATM signaling pathway

(2010) Li-Hsin Chen et al.   BIOCHEMICAL PHARMACOLOGY

The RB-E2F1 Pathway Regulates Autophagy

(2010) H. Jiang et al.   CANCER RESEARCH

The Epidermal Growth Factor Receptor Antibody Cetuximab Induces Autophagy in Cancer Cells by Downregulating HIF-1  and Bcl-2 and Activating the Beclin 1/hVps34 Complex

(2010) X. Li et al.   CANCER RESEARCH

Anoikis triggers Mdm2-dependent p53 degradation

(2010) Abhijit Ghosh et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation

(2010) Rebecca Lock et al.   MOLECULAR BIOLOGY OF THE CELL

p66Shc restrains Ras hyperactivation and suppresses metastatic behavior

(2010) Z Ma et al.   ONCOGENE

Autophagy, senescence and tumor dormancy in cancer therapy

(2009) David A. Gewirtz   Autophagy

Mitophagy

(2009) Aviva M. Tolkovsky   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Role and regulation of autophagy in cancer

(2009) Ning Chen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Silencing of TMS1/ASC Promotes Resistance to Anoikis in Breast Epithelial Cells

(2009) M. J. Parsons et al.   CANCER RESEARCH

Superoxide is the major reactive oxygen species regulating autophagy

(2009) Y Chen et al.   CELL DEATH AND DIFFERENTIATION

Autophagy genes as tumor suppressors

(2009) Chengyu Liang et al.   CURRENT OPINION IN CELL BIOLOGY

Autophagy and metastasis: another double-edged sword

(2009) Candia M Kenific et al.   CURRENT OPINION IN CELL BIOLOGY

Oncogenicras-induced Down-regulation of Autophagy Mediator Beclin-1 Is Required for Malignant Transformation of Intestinal Epithelial Cells

(2009) Byong Hoon Yoo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutation of the Rb1 Pathway Leads to Overexpression of mTor, Constitutive Phosphorylation of Akt on Serine 473, Resistance to Anoikis, and a Block in c-Raf Activation

(2009) S. El-Naggar et al.   MOLECULAR AND CELLULAR BIOLOGY

A Twist-Snail Axis Critical for TrkB-Induced Epithelial-Mesenchymal Transition-Like Transformation, Anoikis Resistance, and Metastasis

(2009) M. A. Smit et al.   MOLECULAR AND CELLULAR BIOLOGY

SIK1 Couples LKB1 to p53-Dependent Anoikis and Suppresses Metastasis

(2009) H. Cheng et al.   Science Signaling

Inhibition of histone deacetylase1 induces autophagy

(2008) Meeyeon Oh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Autophagy and cancer: Dynamism of the metabolism of tumor cells and tissues

(2008) Katsuya Tsuchihara et al.   CANCER LETTERS

Suppression of anoikis by the neurotrophic receptor TrkB in human ovarian cancer

(2008) Xiaohui Yu et al.   CANCER SCIENCE

Mitochondrial DNA depletion in prostate epithelial cells promotes anoikis resistance and invasion through activation of PI3K/Akt2

(2008) L Moro et al.   CELL DEATH AND DIFFERENTIATION

Redox regulation of anoikis: reactive oxygen species as essential mediators of cell survival

(2008) E Giannoni et al.   CELL DEATH AND DIFFERENTIATION

Extracellular matrix regulation of autophagy

(2008) Rebecca Lock et al.   CURRENT OPINION IN CELL BIOLOGY

Autophagy inhibition enhances anthocyanin-induced apoptosis in hepatocellular carcinoma

(2008) L. Longo et al.   MOLECULAR CANCER THERAPEUTICS

Induction of Autophagy during Extracellular Matrix Detachment Promotes Cell Survival

(2007) Christopher Fung et al.   MOLECULAR BIOLOGY OF THE CELL