Molecular Pathways Regulating Macrovascular Pathology and Vascular Smooth Muscle Cells Phenotype in Type 2 Diabetes

Antioxidant Treatment Prevents Serum Deprivation- and TNF-α-Induced Endothelial Dysfunction through the Inhibition of NADPH Oxidase 4 and the Restoration of β-Oxidation

(2017) Maria Giovanna Scioli et al.   JOURNAL OF VASCULAR RESEARCH

Brain natriuretic peptide modulates calcium homeostasis and epidermal growth factor receptor gene signalling in asthmatic airways smooth muscle cells

(2015) Augusto Orlandi et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Powerful anti-tumor and anti-angiogenic activity of a new anti-vascular endothelial growth factor receptor 1 peptide in colorectal cancer models

(2015) Valeria Cicatiello et al.   Oncotarget

The Contribution of Resident Vascular Stem Cells to Arterial Pathology

(2015) Augusto Orlandi   International Journal of Stem Cells

Advanced Application of Porcine Intramuscular Adipocytes for Evaluating Anti-Adipogenic and Anti-Inflammatory Activities of Immunobiotics

(2015) Masahiko Suzuki et al.   PLoS One

Insulin-like Growth Factor-1 Increases Synthesis of Collagen Type I via Induction of the mRNA-binding Protein LARP6 Expression and Binding to the 5′ Stem-loop ofCOL1a1andCOL1a2mRNA

(2014) Christopher D. Blackstock et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High Insulin-Induced Down-Regulation of Erk-1/IGF-1R/FGFR-1 Signaling Is Required for Oxidative Stress-Mediated Apoptosis of Adipose-Derived Stem Cells

(2014) Maria Giovanna Scioli et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Sortilin Expression Is Essential for Pro-Nerve Growth Factor-Induced Apoptosis of Rat Vascular Smooth Muscle Cells

(2014) Luisa Campagnolo et al.   PLoS One

MicroRNA-133a regulates insulin-like growth factor-1 receptor expression and vascular smooth muscle cell proliferation in murine atherosclerosis

(2013) Song Gao et al.   ATHEROSCLEROSIS

Interferon regulatory factor-1 together with reactive oxygen species promotes the acceleration of cell cycle progression by up-regulating the cyclin E and CDK2 genes during high glucose-induced proliferation of vascular smooth muscle cells

(2013) Xi Zhang et al.   Cardiovascular Diabetology

Production of Reactive Oxygen Species in the Diabetic Heart

(2013) Yasushi Teshima et al.   CIRCULATION JOURNAL

The vascular smooth muscle cell: a therapeutic target in Type 2 diabetes?

(2013) Karen E. Porter et al.   CLINICAL SCIENCE

High Glucose Induces Connective Tissue Growth Factor Expression and Extracellular Matrix Accumulation in Rat Aorta Vascular Smooth Muscle Cells Via Extracellular Signal-Regulated Kinase 1/2

(2013) Yu Mi Ha et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

VEGF in the Crosstalk between Human Adipocytes and Smooth Muscle Cells: Depot-Specific Release from Visceral and Perivascular Adipose Tissue

(2013) Raphaela Schlich et al.   MEDIATORS OF INFLAMMATION

Diabetes and aging: a different phenotypic commitment of circulating and resident stem cells?

(2012) Amedeo Ferlosio et al.   ACTA DIABETOLOGICA

Age-related increase of stem marker expression influences vascular smooth muscle cell properties

(2012) Amedeo Ferlosio et al.   ATHEROSCLEROSIS

Platelet-Rich Plasma Greatly Potentiates Insulin-Induced Adipogenic Differentiation of Human Adipose-Derived Stem Cells Through a Serine/Threonine Kinase Akt-Dependent Mechanism and Promotes Clinical Fat Graft Maintenance

(2012) Valerio Cervelli et al.   Stem Cells Translational Medicine

IGF-1 Has Plaque-Stabilizing Effects in Atherosclerosis by Altering Vascular Smooth Muscle Cell Phenotype

(2011) Jan H. von der Thüsen et al.   AMERICAN JOURNAL OF PATHOLOGY

Epigenetic Control of Smooth Muscle Cell Differentiation and Phenotypic Switching in Vascular Development and Disease

(2011) Matthew R. Alexander et al.   Annual Review of Physiology

Inhibition of Reactive Oxygen Species/Extracellular Signal-Regulated Kinases Pathway by Pioglitazone Attenuates Advanced Glycation End Products-Induced Proliferation of Vascular Smooth Muscle Cells in Rats

(2011) Xiaochen Yuan et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Stem cell marker expression, proliferation and apoptosis of vascular smooth muscle cells

(2011) Augusto Orlandi et al.   CELL CYCLE

The Biflavonoid Amentoflavone Inhibits Neovascularization Preventing the Activity of Proangiogenic Vascular Endothelial Growth Factors

(2011) Valeria Tarallo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Propionyl- l -Carnitine Improves Postischemic Blood Flow Recovery and Arteriogenetic Revascularization and Reduces Endothelial NADPH-Oxidase 4–Mediated Superoxide Production

(2010) Maria Antonietta Stasi et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Progenitor cell-derived smooth muscle cells in vascular disease

(2010) Augusto Orlandi et al.   BIOCHEMICAL PHARMACOLOGY

A Placental Growth Factor Variant Unable to Recognize Vascular Endothelial Growth Factor (VEGF) Receptor-1 Inhibits VEGF-Dependent Tumor Angiogenesis via Heterodimerization

(2010) V. Tarallo et al.   CANCER RESEARCH

The Role of Endoplasmic Reticulum Stress in the Progression of Atherosclerosis

(2010) Ira Tabas   CIRCULATION RESEARCH

Cellular mechanisms by which proinsulin C-peptide prevents insulin-induced neointima formation in human saphenous vein

(2010) R. S. Mughal et al.   DIABETOLOGIA

Oleic acid and adipokines synergize in inducing proliferation and inflammatory signalling in human vascular smooth muscle cells

(2010) Daniela Lamers et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Inhibition of IFN Regulatory Factor-1 Down-Regulate Th1 Cell Function in Patients with Acute Coronary Syndrome

(2010) Min Guo et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Molecular mechanism of angiotensin II-induced insulin resistance in aortic vascular smooth muscle cells: Roles of Protein Tyrosine Phosphatase-1B

(2010) Pimonrat Ketsawatsomkron et al.   VASCULAR PHARMACOLOGY

Inherent differences in morphology, proliferation, and migration in saphenous vein smooth muscle cells cultured from nondiabetic and Type 2 diabetic patients

(2009) Haifa A. Madi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Insulin-Like Growth Factor-1 Receptor Expression Masks the Antiinflammatory and Glucose Uptake Capacity of Insulin in Vascular Smooth Muscle Cells

(2009) Niels Engberding et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Flt-1 expression influences apoptotic susceptibility of vascular smooth muscle cells through the NF-κB/IAP-1 pathway

(2009) Augusto Orlandi et al.   CARDIOVASCULAR RESEARCH

Cardiovascular Effects of Disturbed Insulin Activity in Metabolic Syndrome and in Type 2 Diabetic Patients

(2009) T. Forst et al.   HORMONE AND METABOLIC RESEARCH

The Pathologic Continuum of Diabetic Vascular Disease

(2009) Gabriela Orasanu et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Human proinsulin C-peptide reduces high glucose-induced proliferation and NF-κB activation in vascular smooth muscle cells

(2008) Vincenza Cifarelli et al.   ATHEROSCLEROSIS

Do cardiac and perivascular adipose tissue play a role in atherosclerosis?

(2008) Gianluca Iacobellis et al.   Current Diabetes Reports

Diabetes and atherosclerosis: is there a role for hyperglycemia?

(2008) Alan Chait et al.   JOURNAL OF LIPID RESEARCH