MicroRNAs: Clinical Relevance in Colorectal Cancer

MicroRNA-101 down-regulates sphingosine kinase 1 in colorectal cancer cells

(2015) Min-Bin Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Factors associated with use and non-use of the Fecal Immunochemical Test (FIT) kit for Colorectal Cancer Screening in Response to a 2012 outreach screening program: a survey study

(2015) Nancy P. Gordon et al.   BMC PUBLIC HEALTH

MicroRNAs in cancer: from developmental genes in worms to their clinical application in patients

(2015) M Pichler et al.   BRITISH JOURNAL OF CANCER

MicroRNA214 Is Associated With Progression of Ulcerative Colitis, and Inhibition Reduces Development of Colitis and Colitis-Associated Cancer in Mice

(2015) Christos Polytarchou et al.   GASTROENTEROLOGY

The clinical and biological significance of MIR-224 expression in colorectal cancer metastasis

(2015) Hui Ling et al.   GUT

miRNA-26b Overexpression in Ulcerative Colitis-associated Carcinogenesis

(2015) Natalya Benderska et al.   INFLAMMATORY BOWEL DISEASES

MicroRNA-520g Confers Drug Resistance by Regulating p21 Expression in Colorectal Cancer

(2015) Yang Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Screening for Lynch syndrome and referral to clinical genetics by selective mismatch repair protein immunohistochemistry testing: an audit and cost analysis

(2015) Richard Colling et al.   JOURNAL OF CLINICAL PATHOLOGY

How MicroRNAs Modify Protein Production

(2015) Jessica L Feig et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Identification of a Metastasis-Specific MicroRNA Signature in Human Colorectal Cancer

(2015) Keun Hur et al.   JNCI-Journal of the National Cancer Institute

Novel plasma microRNA biomarkers for the identification of colitis-associated carcinoma

(2015) Maleene Patel et al.   LANCET

Identification of a Metastasis-Specific MicroRNA Signature in Human Colorectal Cancer

(2015) Keun Hur et al.   JNCI-Journal of the National Cancer Institute

MicroRNA-17-5p promotes chemotherapeutic drug resistance and tumour metastasis of colorectal cancer by repressing PTEN expression

(2015) Lekun Fang et al.   Oncotarget

microRNA-221 and microRNA-18a identification in stool as potential biomarkers for the non-invasive diagnosis of colorectal carcinoma

(2014) T O Yau et al.   BRITISH JOURNAL OF CANCER

Colorectal cancer statistics, 2014

(2014) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Polymorphisms in microRNA genes as predictors of clinical outcomes in colorectal cancer patients

(2014) Barbara Pardini et al.   CARCINOGENESIS

MicroRNA-7expression in colorectal cancer is associated with poor prognosis and regulates cetuximab sensitivity viaEGFRregulation

(2014) Toshinaga Suto et al.   CARCINOGENESIS

MicroRNA-96 promotes the proliferation of colorectal cancer cells and targets tumor protein p53 inducible nuclear protein 1, forkhead box protein O1 (FOXO1) and FOXO3a

(2014) FENG GAO et al.   Molecular Medicine Reports

Regulation of microRNA biogenesis

(2014) Minju Ha et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

MicroRNA-147 Induces a Mesenchymal-To-Epithelial Transition (MET) and Reverses EGFR Inhibitor Resistance

(2014) Chang Gong Lee et al.   PLoS One

MiR-143 and MiR-145 Regulate IGF1R to Suppress Cell Proliferation in Colorectal Cancer

(2014) Jiaojiao Su et al.   PLoS One

Determinants of recurrence after intended curative resection for colorectal cancer

(2014) Michael Wilhelmsen et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

MicroRNAs as novel predictive biomarkers and therapeutic targets in colorectal cancer

(2014) Verena Stiegelbauer   WORLD JOURNAL OF GASTROENTEROLOGY

MiR-194 Deregulation Contributes To Colorectal Carcinogenesis via Targeting AKT2 Pathway

(2014) Hui-Jun Zhao et al.   Theranostics

A Plasma MicroRNA Panel for Detection of Colorectal Adenomas

(2013) Ziad Kanaan et al.   ANNALS OF SURGERY

Serum miR-200c Is a Novel Prognostic and Metastasis-Predictive Biomarker in Patients With Colorectal Cancer

(2013) Yuji Toiyama et al.   ANNALS OF SURGERY

MicroRNA-126 and epidermal growth factor-like domain 7–an angiogenic couple of importance in metastatic colorectal cancer. Results from the Nordic ACT trial

(2013) T F Hansen et al.   BRITISH JOURNAL OF CANCER

Identification of serum microRNA profiles in colon cancer

(2013) E Hofsli et al.   BRITISH JOURNAL OF CANCER

Fecal miR-106a Is a Useful Marker for Colorectal Cancer Patients with False-Negative Results in Immunochemical Fecal Occult Blood Test

(2013) Y. Koga et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

MicroRNA Signature in Metastatic Colorectal Cancer Patients Treated With Anti-EGFR Monoclonal Antibodies

(2013) Federico Cappuzzo et al.   Clinical Colorectal Cancer

MicroRNA-92a Functions as an Oncogene in Colorectal Cancer by Targeting PTEN

(2013) Guangjun Zhang et al.   DIGESTIVE DISEASES AND SCIENCES

miR-181a is associated with poor clinical outcome in patients with colorectal cancer treated with EGFR inhibitor

(2013) Martin Pichler et al.   JOURNAL OF CLINICAL PATHOLOGY

miR-203 induces oxaliplatin resistance in colorectal cancer cells by negatively regulating ATM kinase

(2013) Yunfei Zhou et al.   Molecular Oncology

High expression of microRNA-625-3p is associated with poor response to first-line oxaliplatin based treatment of metastatic colorectal cancer

(2013) Mads H. Rasmussen et al.   Molecular Oncology

MicroRNAs and other non-coding RNAs as targets for anticancer drug development

(2013) Hui Ling et al.   NATURE REVIEWS DRUG DISCOVERY

miRNA-27b Targets Vascular Endothelial Growth Factor C to Inhibit Tumor Progression and Angiogenesis in Colorectal Cancer

(2013) Jun Ye et al.   PLoS One

MicroRNA-320a suppresses human colon cancer cell proliferation by directly targeting β-catenin

(2012) Jian-Yong Sun et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Downregulation of miR-145 associated with cancer progression and VEGF transcriptional activation by targeting N-RAS and IRS1

(2012) Yu Yin et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Genetic Polymorphisms in Pre-microRNA Genes as Prognostic Markers of Colorectal Cancer

(2012) J. Xing et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Downregulation of miR-144 is associated with colorectal cancer progression via activation of mTOR signaling pathway

(2012) Takeshi Iwaya et al.   CARCINOGENESIS

MiR-222 modulates multidrug resistance in human colorectal carcinoma by down-regulating ADAM-17

(2012) Ke Xu et al.   EXPERIMENTAL CELL RESEARCH

MicroRNA-200c modulates epithelial-to-mesenchymal transition (EMT) in human colorectal cancer metastasis

(2012) Keun Hur et al.   GUT

Differential MicroRNA expression tracks neoplastic progression in inflammatory bowel disease-associated colorectal cancer

(2012) Ziad Kanaan et al.   HUMAN MUTATION

MiR-21 regulates biological behavior through the PTEN/PI-3 K/Akt signaling pathway in human colorectal cancer cells

(2012) BINGHONG XIONG et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

High Let-7a MicroRNA Levels in KRAS-Mutated Colorectal Carcinomas May Rescue Anti-EGFR Therapy Effects in Patients with Chemotherapy-Refractory Metastatic Disease

(2012) A. Ruzzo et al.   ONCOLOGIST

microRNA-365, down-regulated in colon cancer, inhibits cell cycle progression and promotes apoptosis of colon cancer cells by probably targeting Cyclin D1 and Bcl-2

(2011) Jing Nie et al.   CARCINOGENESIS

MicroRNA-21 induces stemness by downregulating transforming growth factor beta receptor 2 (TGF R2) in colon cancer cells

(2011) Y. Yu et al.   CARCINOGENESIS

MicroRNA 506 regulates expression of PPAR alpha in hydroxycamptothecin-resistant human colon cancer cells

(2011) Jin Lu Tong et al.   FEBS LETTERS

Detection of miR-92a and miR-21 in stool samples as potential screening biomarkers for colorectal cancer and polyps

(2011) Chung Wah Wu et al.   GUT

MicroRNAs in colorectal cancer metastasis

(2011) Inge de Krijger et al.   JOURNAL OF PATHOLOGY

Circulating Plasma MiR-141 Is a Novel Biomarker for Metastatic Colon Cancer and Predicts Poor Prognosis

(2011) Hanyin Cheng et al.   PLoS One

microRNA-195 promotes apoptosis and suppresses tumorigenicity of human colorectal cancer cells

(2010) Lin Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Targeting Wnt Signaling in Colon Cancer Stem Cells

(2010) E. M. F. de Sousa et al.   CLINICAL CANCER RESEARCH

MicroRNAs and colon and rectal cancer: Differential expression by tumor location and subtype

(2010) Martha L. Slattery et al.   GENES CHROMOSOMES & CANCER

miR-21 and miR-31 Converge on TIAM1 to Regulate Migration and Invasion of Colon Carcinoma Cells

(2010) Charisa L. Cottonham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human embryonic stem cells and metastatic colorectal cancer cells shared the common endogenous human microRNA-26b

(2010) Yan-Lei Ma et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

miR-192/miR-215 Influence 5-Fluorouracil Resistance through Cell Cycle-Mediated Mechanisms Complementary to Its Post-transcriptional Thymidilate Synthase Regulation

(2010) Valentina Boni et al.   MOLECULAR CANCER THERAPEUTICS

Role of primary miRNA polymorphic variants in metastatic colon cancer patients treated with 5-fluorouracil and irinotecan

(2010) V Boni et al.   PHARMACOGENOMICS JOURNAL

Modulation of mismatch repair and genomic stability by miR-155

(2010) N. Valeri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

American College of Gastroenterology Guidelines for Colorectal Cancer Screening 2008

(2009) Douglas K Rex et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

MicroRNAs in Cancer

(2009) Ramiro Garzon et al.   Annual Review of Medicine

Annual report to the nation on the status of cancer, 1975-2006, featuring colorectal cancer trends and impact of interventions (risk factors, screening, and treatment) to reduce future rates

(2009) Brenda K. Edwards et al.   CANCER

The miR-18a* microRNA functions as a potential tumor suppressor by targeting on K-Ras

(2009) Wing Pui Tsang et al.   CARCINOGENESIS

MicroRNA-143 reduces viability and increases sensitivity to 5-fluorouracil in HCT116 human colorectal cancer cells

(2009) Pedro M. Borralho et al.   FEBS Journal

Differential expression of microRNAs in plasma of patients with colorectal cancer: a potential marker for colorectal cancer screening

(2009) E K O Ng et al.   GUT

Plasma microRNAs are promising novel biomarkers for early detection of colorectal cancer

(2009) Zhaohui Huang et al.   INTERNATIONAL JOURNAL OF CANCER

Functional screening identifies a microRNA, miR-491 that induces apoptosis by targeting Bcl-XL in colorectal cancer cells

(2009) Haruo Nakano et al.   INTERNATIONAL JOURNAL OF CANCER

Role of miR-143 targeting KRAS in colorectal tumorigenesis

(2009) X Chen et al.   ONCOGENE

Mechanism of chemoresistance mediated by miR-140 in human osteosarcoma and colon cancer cells

(2009) B Song et al.   ONCOGENE

Colorectal Cancer Epidemiology: Incidence, Mortality, Survival, and Risk Factors

(2009) Fatima Haggar et al.   Clinics in Colon and Rectal Surgery

Regulation of the Adenomatous Polyposis Coli Gene by the miR-135 Family in Colorectal Cancer

(2008) R. Nagel et al.   CANCER RESEARCH

miR-192 Regulates Dihydrofolate Reductase and Cellular Proliferation through the p53-microRNA Circuit

(2008) B. Song et al.   CLINICAL CANCER RESEARCH

MicroRNA-21 Targets Sprouty2 and Promotes Cellular Outgrowths

(2008) Danish Sayed et al.   MOLECULAR BIOLOGY OF THE CELL

miR-34a repression of SIRT1 regulates apoptosis

(2008) M. Yamakuchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circulating microRNAs as stable blood-based markers for cancer detection

(2008) P. S. Mitchell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA