MicroRNA (miRNA) Signaling in the Human CNS in Sporadic Alzheimer’s Disease (AD)-Novel and Unique Pathological Features

Environmental control of microRNAs in the nervous system: Implications in plasticity and behavior

(2016) Juan F. Codocedo et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

microRNA-34a-Mediated Down-Regulation of the Microglial-Enriched Triggering Receptor and Phagocytosis-Sensor TREM2 in Age-Related Macular Degeneration

(2016) Surjyadipta Bhattacharjee et al.   PLoS One

Re-thinking miRNA-mRNA interactions: Intertwining issues confound target discovery

(2015) Nicole Cloonan   BIOESSAYS

Principles of miRNA–mRNA interactions: beyond sequence complementarity

(2015) Fabian Afonso-Grunz et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Pre-analytical and analytical factors influencing Alzheimer's disease cerebrospinal fluid biomarker variability

(2015) Anthony Fourier et al.   CLINICA CHIMICA ACTA

MicroRNA Landscape in Alzheimer’s Disease

(2015) Carlo Cogoni et al.   CNS & Neurological Disorders-Drug Targets

Reactive Oxygen Species, Redox Signaling and Neuroinflammation in Alzheimer's Disease: The NF-κB Connection

(2015) Upinder Kaur et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

MicroRNAs are essential for differentiation of the retinal pigmented epithelium and maturation of adjacent photoreceptors

(2015) R. Ohana et al.   DEVELOPMENT

Targeting MicroRNAs in Prevention and Treatment of Neurodegenerative Disorders

(2015) Smriti Gupta et al.   DRUG DEVELOPMENT RESEARCH

Significance of NF-κB as a pivotal therapeutic target in the neurodegenerative pathologies of Alzheimer’s disease and multiple sclerosis

(2015) Mythily Srinivasan et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

The Long, the Short, and the Unstructured: A Unifying Model of miRNA Biogenesis

(2015) Rémy Denzler et al.   MOLECULAR CELL

The Menu of Features that Define Primary MicroRNAs and Enable De Novo Design of MicroRNA Genes

(2015) Wenwen Fang et al.   MOLECULAR CELL

Analysis of RNA from Alzheimer’s Disease Post-mortem Brain Tissues

(2015) Christian Clement et al.   MOLECULAR NEUROBIOLOGY

microRNA (miRNA)-Mediated Pathogenetic Signaling in Alzheimer’s Disease (AD)

(2015) James M. Hill et al.   NEUROCHEMICAL RESEARCH

General hallmarks of microRNAs in brain evolution and development

(2015) Wei Chen et al.   RNA Biology

The regulation of exosome function in the CNS: implications for neurodegeneration

(2015) F Properzi et al.   SWISS MEDICAL WEEKLY

Microbial-generated amyloids and Alzheimer's disease (AD)

(2015) James M. Hill et al.   Frontiers in Aging Neuroscience

Induction of the pro-inflammatory NF-kB-sensitive miRNA-146a by human neurotrophic viruses

(2015) James M. Hill et al.   Frontiers in Microbiology

Increase in NF-κB-sensitive miRNA-146a and miRNA-155 in multiple sclerosis (MS) and pro-inflammatory neurodegeneration

(2015) Deidre J. Devier et al.   Frontiers in Molecular Neuroscience

Role of MicroRNAs in innate neuroprotection mechanisms due to preconditioning of the brain

(2015) Eva M. Jimenez-Mateos   Frontiers in Neuroscience

The emerging role of microRNAs in Alzheimer's disease

(2015) Grazia D. Femminella et al.   Frontiers in Physiology

Emerging Roles of Exosomes in Normal and Pathological Conditions: New Insights for Diagnosis and Therapeutic Applications

(2015) Julieta De Toro et al.   Frontiers in Immunology

Pathogenic microRNAs Common to Brain and Retinal Degeneration; Recent Observations in Alzheimer’s Disease and Age-Related Macular Degeneration

(2015) James M. Hill et al.   Frontiers in Neurology

NF-κB in Innate Neuroprotection and Age-Related Neurodegenerative Diseases

(2015) Annamaria Lanzillotta et al.   Frontiers in Neurology

microRNA-Based Biomarkers and the Diagnosis of Alzheimer’s Disease

(2015) Yuhai Zhao et al.   Frontiers in Neurology

Plasma Exosomal miRNAs in Persons with and without Alzheimer Disease: Altered Expression and Prospects for Biomarkers

(2015) Giovanni Lugli et al.   PLoS One

Deciphering the Function and Regulation of microRNAs in Alzheimer’s Disease and Parkinson’s Disease

(2014) Lifeng Qiu et al.   ACS Chemical Neuroscience

MicroRNA (miRNA): Sequence and stability, viroid-like properties, and disease association in the CNS

(2014) Aileen I. Pogue et al.   BRAIN RESEARCH

A Functional SNP Catalog of Overlapping miRNA-Binding Sites in Genes Implicated in Prion Disease and Other Neurodegenerative Disorders

(2014) Reuben Saba et al.   HUMAN MUTATION

Beta-Amyloid Precursor Protein (βAPP) Processing in Alzheimer’s Disease (AD) and Age-Related Macular Degeneration (AMD)

(2014) Yuhai Zhao et al.   MOLECULAR NEUROBIOLOGY

Causes and Consequences of MicroRNA Dysregulation in Neurodegenerative Diseases

(2014) Lin Tan et al.   MOLECULAR NEUROBIOLOGY

Role of nuclear factor kappa B in central nervous system regeneration

(2014) Ronny Haenold et al.   Neural Regeneration Research

Variability of CSF Alzheimer’s Disease Biomarkers: Implications for Clinical Practice

(2014) Stephanie J. B. Vos et al.   PLoS One

Microdissection and transcriptional profiling

(2014) Anna Majer et al.   Prion

Regulating amyloidogenesis through the natural triggering receptor expressed in myeloid/microglial cells 2 (TREM2)

(2014) Brandon M. Jones et al.   Frontiers in Cellular Neuroscience

Deficits in the miRNA-34a-regulated endogenous TREM2 phagocytosis sensor-receptor in Alzheimer's disease (AD); an update

(2014) Surjyadipta Bhattacharjee et al.   Frontiers in Aging Neuroscience

MicroRNAs in the Neural Retina

(2014) Kalina Andreeva et al.   International Journal of Genomics

miRNAs and viroids utilize common strategies in genetic signal transfer

(2014) James M. Hill et al.   Frontiers in Molecular Neuroscience

A non-canonical landscape of the microRNA system

(2014) Gabriel A. Cipolla   Frontiers in Genetics

Identification of active transcription factor and miRNA regulatory pathways in Alzheimer’s disease

(2013) Wei Jiang et al.   BIOINFORMATICS

Expression of the phagocytosis-essential protein TREM2 is down-regulated by an aluminum-induced miRNA-34a in a murine microglial cell line

(2013) Peter N. Alexandrov et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Regulation of Neurotropic Signaling by the Inducible, NF-kB-Sensitive miRNA-125b in Alzheimer's Disease (AD) and in Primary Human Neuronal-Glial (HNG) Cells

(2013) Yuhai Zhao et al.   MOLECULAR NEUROBIOLOGY

Regulation of TREM2 expression by an NF-кB-sensitive miRNA-34a

(2013) Yuhai Zhao et al.   NEUROREPORT

TREM2 signaling, miRNA-34a and the extinction of phagocytosis

(2013) Yuhai Zhao et al.   Frontiers in Cellular Neuroscience

Variability in micro RNA (miRNA) abundance, speciation and complexity amongst different human populations and potential relevance to Alzheimer's disease (AD)

(2013) Walter J. Lukiw   Frontiers in Cellular Neuroscience

Studying micro RNA Function and Dysfunction in Alzheimer’s Disease

(2013) Walter J. Lukiw et al.   Frontiers in Genetics

Antagonism of NF-κB-up-regulated micro RNAs (miRNAs) in sporadic Alzheimer's disease (AD)—anti-NF-κB vs. anti-miRNA strategies

(2013) Walter J. Lukiw   Frontiers in Genetics

MicroRNAs, new effectors and regulators of NF-κB

(2012) Mark P. Boldin et al.   IMMUNOLOGICAL REVIEWS

Regulation of Complement Factor H (CFH) by Multiple miRNAs in Alzheimer’s Disease (AD) Brain

(2012) Walter J. Lukiw et al.   MOLECULAR NEUROBIOLOGY

MicroRNA turnover: when, how, and why

(2012) Stefan Rüegger et al.   TRENDS IN BIOCHEMICAL SCIENCES

NF-κB-regulated, proinflammatory miRNAs in Alzheimer's disease

(2012) Walter J Lukiw   Alzheimers Research & Therapy

MicroRNA degradation and turnover: regulating the regulators

(2012) Zhuo Zhang et al.   Wiley Interdisciplinary Reviews-RNA

Evolution and Complexity of Micro RNA in the Human Brain

(2012) Walter J. Lukiw   Frontiers in Genetics

NF-кB-regulated micro RNAs (miRNAs) in primary human brain cells

(2011) Walter J. Lukiw   EXPERIMENTAL NEUROLOGY

Up-regulation of NF-kB-sensitive miRNA-125b and miRNA-146a in metal sulfate-stressed human astroglial (HAG) primary cell cultures

(2011) Aileen I. Pogue et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Upregulation of Micro RNA-146a (miRNA-146a), A Marker for Inflammatory Neurodegeneration, in Sporadic Creutzfeldt–Jakob Disease (sCJD) and Gerstmann–Straussler–Scheinker (GSS) Syndrome

(2011) W. J. Lukiw et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

MicroRNAs can generate thresholds in target gene expression

(2011) Shankar Mukherji et al.   NATURE GENETICS

miRNA-155 upregulation and complement factor H deficits in Down’s syndrome

(2011) Yuan Y. Li et al.   NEUROREPORT

Differential expression of miRNA-146a-regulated inflammatory genes in human primary neural, astroglial and microglial cells

(2011) Yuan Yuan Li et al.   NEUROSCIENCE LETTERS

Differential Regulation of Interleukin-1 Receptor-associated Kinase-1 (IRAK-1) and IRAK-2 by MicroRNA-146a and NF-κB in Stressed Human Astroglial Cells and in Alzheimer Disease

(2010) Jian Guo Cui et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mammalian microRNAs predominantly act to decrease target mRNA levels

(2010) Huili Guo et al.   NATURE

Acyclovir or Aβ42 peptides attenuate HSV-1-induced miRNA-146a levels in human primary brain cells

(2010) Walter J. Lukiw et al.   NEUROREPORT

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

HSV-1 infection of human brain cells induces miRNA-146a and Alzheimer-type inflammatory signaling

(2009) James M. Hill et al.   NEUROREPORT

Micro-RNA abundance and stability in human brain: Specific alterations in Alzheimer's disease temporal lobe neocortex

(2009) Prerna Sethi et al.   NEUROSCIENCE LETTERS

Selectivity of the NF- B Response

(2009) R. Sen et al.   Cold Spring Harbor Perspectives in Biology

An NF-κB-sensitive Micro RNA-146a-mediated Inflammatory Circuit in Alzheimer Disease and in Stressed Human Brain Cells

(2008) Walter J. Lukiw et al.   JOURNAL OF BIOLOGICAL CHEMISTRY