p53-Dependent and Cell Specific Epigenetic Regulation of the Polo-like kinases under Oxidative Stress

The expression of Nek7, FoxM1, and Plk1 in gallbladder cancer and their relationships to clinicopathologic features and survival

(2013) R. Wang et al.   Clinical & Translational Oncology

SAPK pathways and p53 cooperatively regulate PLK4 activity and centrosome integrity under stress

(2013) Takanori Nakamura et al.   Nature Communications

Oxidative stress and cancer: An overview

(2012) Venus Sosa et al.   AGEING RESEARCH REVIEWS

Mutant p53 oncogenic functions are sustained by Plk2 kinase through an autoregulatory feedback loop

(2012) Fabio Valenti et al.   CELL CYCLE

Liver Cancer and Alcohol

(2012) Priya Grewal et al.   Clinics in Liver Disease

Polo-Like Kinases Inhibitors

(2012) L. Garuti et al.   CURRENT MEDICINAL CHEMISTRY

Methylation of RASSF1A gene promoter is regulated by p53 and DAXX

(2012) Hailong Zhang et al.   FASEB JOURNAL

Apparent versus true gene expression changes of three hypoxia-related genes in autopsy derived tissue and the importance of normalisation

(2012) Antje Huth et al.   INTERNATIONAL JOURNAL OF LEGAL MEDICINE

Discrimination of genotoxic and non-genotoxic hepatocarcinogens by statistical analysis based on gene expression profiling in the mouse liver as determined by quantitative real-time PCR

(2012) Takashi Watanabe et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Downregulation of Polo-Like Kinase 4 in Hepatocellular Carcinoma Associates with Poor Prognosis

(2012) Lili Liu et al.   PLoS One

Clinical Results With the DNA Hypomethylating Agent 5-Aza-2′-Deoxycytidine (Decitabine) in Patients With Myelodysplastic Syndromes: An Update

(2012) Tina E. Joeckel et al.   SEMINARS IN HEMATOLOGY

Epigenetic changes induced by oxidative stress in colorectal cancer cells: methylation of tumor suppressor RUNX3

(2012) Kyoung Ah Kang et al.   TUMOR BIOLOGY

Aberrant methylation of Polo-like kinase CpG islands in Plk4 heterozygous mice

(2011) Alejandra Ward et al.   BMC CANCER

Oxidative Damage Targets Complexes Containing DNA Methyltransferases, SIRT1, and Polycomb Members to Promoter CpG Islands

(2011) Heather M. O'Hagan et al.   CANCER CELL

Polo-like Kinase Plk2 Is an Epigenetic Determinant of Chemosensitivity and Clinical Outcomes in Ovarian Cancer

(2011) N. Syed et al.   CANCER RESEARCH

The p53 target Plk2 interacts with TSC proteins impacting mTOR signaling, tumor growth, and chemosensitivity under hypoxic conditions

(2011) Elizabeth M. Matthew et al.   CELL CYCLE

From Plk1 to Plk5

(2011) Guillermo de Cárcer et al.   CELL CYCLE

PLK1 as an oncology target: current status and future potential

(2011) Campbell McInnes et al.   DRUG DISCOVERY TODAY

Hypoxia-Induced Epigenetic Regulation and Silencing of the BRCA1 Promoter

(2011) Y. Lu et al.   MOLECULAR AND CELLULAR BIOLOGY

Plk5, a Polo Box Domain-Only Protein with Specific Roles in Neuron Differentiation and Glioblastoma Suppression

(2011) G. de Carcer et al.   MOLECULAR AND CELLULAR BIOLOGY

Plk1-targeted small molecule inhibitors: molecular basis for their potency and specificity

(2011) Ravichandran N. Murugan et al.   MOLECULES AND CELLS

Reactive Oxygen Species (ROS)––Induced genetic and epigenetic alterations in human carcinogenesis

(2011) Dominique Ziech et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Analysis of p53 mutation status in human cancer cell lines: a paradigm for cell line cross-contamination

(2010) Hanna Berglind et al.   CANCER BIOLOGY & THERAPY

p53-dependent repression of polo-like kinase-1 (PLK1)

(2010) Lynsey McKenzie et al.   CELL CYCLE

A Seven-Gene Set Associated with Chronic Hypoxia of Prognostic Importance in Hepatocellular Carcinoma

(2010) H. van Malenstein et al.   CLINICAL CANCER RESEARCH

Dnmt3/transcription factor interactions as crucial players in targeted DNA methylation

(2010) Eric Hervouet et al.   Epigenetics

Multivalent epigenetic marks confer microenvironment-responsive epigenetic plasticity to ovarian cancer cells

(2010) Sharmila A. Bapat et al.   Epigenetics

Ischemia dysregulates DNA methyltransferases andp16INK4amethylation in human colorectal cancer cells

(2010) Karolina Skowronski et al.   Epigenetics

Inflammation, HIF-1, and the Epigenetics That Follows

(2010) Claudio Brigati et al.   MEDIATORS OF INFLAMMATION

The novel mouse Polo-like kinase 5 responds to DNA damage and localizes in the nucleolus

(2010) Zdenek Andrysik et al.   NUCLEIC ACIDS RESEARCH

Gene expression patterns in heterozygous Plk4 murine embryonic fibroblasts

(2009) Alan Morettin et al.   BMC GENOMICS

Microenvironmental regulation of cancer development

(2008) Min Hu et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Epigenetic Changes Induced by Reactive Oxygen Species in Hepatocellular Carcinoma: Methylation of the E-cadherin Promoter

(2008) Seung-Oe Lim et al.   GASTROENTEROLOGY