Article
Nanoscience & Nanotechnology
Vitor M. Miguel, Maria Paula de S. Rodrigues, Adriano H. Braga, Susana I. Cordoba de Torresi
Summary: This study demonstrates that the catalytic activity of MnO2 can be greatly improved by the localized surface plasmon resonance (LSPR) effect when decorated with gold nanoparticles (Au NPs). Under visible light irradiation, the gold decorated nanowires show higher sensitivity and increased current for H2O2 oxidation. The improved performance is attributed to more efficient charge separation by plasmonic generated hot electrons and holes.
ACS APPLIED NANO MATERIALS
(2022)
Article
Materials Science, Ceramics
Lei Chen, Wenting Sun, Zhiying Xu, Minghui Hao, Baojing Li, Xin Liu, Jingjing Ma, Liang Wang, Chunhu Li, Wentai Wang
Summary: This study reports a binary catalyst Cu/P-TiO2 for low-temperature electrocatalytic reduction of nitric oxide (NORR). The catalyst takes advantages of Cu electrocatalysts and porous TiO2, exhibiting excellent electrocatalytic activity and high Faraday efficiency.
CERAMICS INTERNATIONAL
(2022)
Article
Engineering, Environmental
Yaru Li, Yong-Chen Miao, Chen Yang, Yu-Xin Chang, Yu Su, Hong Yan, Sailong Xu
Summary: Developing low-cost and high-performance electrocatalysts is crucial for advancing hydrogen production. In this study, a composite of Ir nanodots decorated Ni3Fe alloy on reduced graphene oxide (Ir/Ni3Fe/rGO) is prepared as a bifunctional electrocatalyst for water splitting. The composite exhibits attractive electrocatalytic performances, requiring low overpotentials for the oxygen and hydrogen evolution reactions. Furthermore, an electrolyzer assembled with this electrocatalyst achieves a high cell voltage for overall water splitting, outperforming other catalysts. The results provide an effective strategy for designing low-cost and promising electrocatalysts for water splitting.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Analytical
Juyoung Kang, Hyungjun Jang, Gyuho Yeom, Min-Gon Kim
Summary: The study developed a protein detection method based on a heterogeneous sandwich-type sensing platform, which can achieve high specificity and sensitivity. This method can detect biomarkers in various infectious diseases, including SARS-CoV-2, with low cross-reactivity. Clinical sample testing confirmed the effectiveness of the proposed method.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Ahmed Gamal El-Shamy
Summary: A Schottky device based on carbon dots decorated magnesium oxide nanoparticles has been engineered for H2S gas sensing applications, displaying high response and sensitivity due to reduced barrier height between crystals.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Multidisciplinary
Yi Zhang, Zongyi You, Chunsheng Hou, Liangliang Liu, Aiping Xiao
Summary: The novel electrochemical sensor Fe3O4-NH2-GN/GCE, prepared for detection of CBD, showed good detection limit and linear range, with results consistent with HPLC method for CBD detection in Cannabis sativa leaf extract.
Article
Chemistry, Analytical
Patrycja Plocienniczak, Tomasz Rebis, Marek Nowicki, Grzegorz Milczarek
Summary: This study developed a green and simple method for fabricating multi-walled carbon nanotubes decorated with silver nanoparticles using lignosulfonate assistance. The silver nanoparticles showed strong electrocatalytic properties towards hydrogen peroxide reduction and enabled a wide linear range for detection. The material exhibited promising electrochemical performance for hydrogen peroxide sensing applications.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Liran Tian, Xiangwei Song, Tianjiao Liu, Anfeng Li, Yang Ning, Xiuyi Hua, Deming Dong, Dapeng Liang
Summary: A UV-Visible and fluorescence detection method was designed for the determination of acetamiprid based on the specific identification ability of aptamers. The presence of acetamiprid could be clearly determined through the aggregation of gold nanoparticles and the redshifting of the UV-vis absorption peak. This combined method showed a wide detection range and a low detection limit, making it a potential simple method for the determination of acetamiprid residues in natural water bodies.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Analytical
Chia-Ying Chin, Cheng-cheung Chen, Xin-an Chen, Hui-ju Yen, Hsin-lun Hsien, Jenn-jong Young, Yin-chuan Chen
Summary: An extremely sensitive and ultra-low-cost PVDF-based SERS substrate has been developed for trace-level detection of small molecules and bacterial spores. The simple fabrication process allows for laboratory-scale use and industrial applications, with impressive detection limits and signal enhancement. The substrate shows potential for rapid, sensitive, and high-throughput detection in a cost-effective manner.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Multidisciplinary
Simone Brannetti, Serena Gentile, Alejandro Chamorro-Garcia, Luca Barbero, Erica Del Grosso, Francesco Ricci
Summary: In this study, we have developed Lateral Flow Assays (LFAs) using DNA-based structures decorated with reporter tags and recognition elements as functional elements. By re-engineering tile-based DNA tubular structures, we can decorate them with recognition elements of different nature and orthogonal fluorescent dyes, enabling the detection of a wide range of targets with nanomolar sensitivity and high specificity using sandwich and competitive multiplex lateral flow platforms.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Biophysics
Chunlan Deng, Qilai Zhao, Yichuan Gan, Changsheng Yang, Hongbo Zhu, Shiman Mo, Junjie Zheng, Jialong Li, Kui Jiang, Zhouming Feng, Xiaoming Wei, Qinyuan Zhang, Zhongmin Yang, Shanhui Xu
Summary: This study presents a novel strategy for high-sensitivity hemoglobin detection, utilizing polarization-differential spectrophotometry and high-performance single-frequency green fiber laser. By accurately extracting the two-dimensional information of intensity and polarization during the interaction between laser and hemoglobin, and reducing scattered disturbance, the detection sensitivity of trace hemoglobin content has been significantly improved. This technology holds promising applications in precision medicine and early diagnosis.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Chemistry, Physical
Ling Ouyang, Luchao Yue, Qin Liu, Qian Liu, Zerong Li, Shengjun Sun, Yongsong Luo, Abdulmohsen Ali Alshehri, Mohamed S. Hamdy, Qingquan Kong, Xuping Sun
Summary: This work proposes a high-active catalyst, Cu nanoparticles decorated juncus-derived carbon, for the conversion of nitrite to ammonia, achieving high Faradaic efficiency and satisfactory yield. The study also provides insightful understanding of the internal catalytic mechanism through computational calculations.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Nagesh Bhat, Shareefraza J. Ukkund, Momin Ashraf, Krishnaraja Acharya, Naveenkumar J. Ramegouda, Prasad Puthiyillam, Mohd Abul Hasan, Saiful Islam, Vinaya B. Koradoor, Adarsh D. Praveen, Mohammad Amir Khan
Summary: Gas sensors based on graphene oxide (GO) and copper oxide (CuO) semiconductor nanomaterials were prepared and used for the detection of carbon dioxide. The sensor showed a good sensing response of 60% when tested with an Arduino microcontroller detection unit.
Article
Chemistry, Physical
Ravari Kandy Aparna, Vishnu Surendran, Diptendu Roy, Biswarup Pathak, Manikoth M. Shaijumon, Sukhendu Mandal
Summary: In this study, silver nanoparticle (Ag NP)-incorporated defective, thiol-functionalized UiO-66 metal-organic frameworks (MOFs) were used as a catalyst for the electrocatalytic conversion of CO2 to CO. The Ag@UiO-66-SH catalyst exhibited a high Faradaic efficiency (FE) of 74% and a partial current density of 19.5 mA cm-2 at -1.1 V vs a reversible hydrogen electrode. It showed excellent catalytic stability and a mass-specific activity of 218 A g-1. Density functional theory calculations supported the enhanced catalytic CO2 reduction reaction (CO2RR) activity of Ag@UiO-66-SH compared to the pristine MOFs.
ACS APPLIED ENERGY MATERIALS
(2023)
Article
Chemistry, Analytical
Suzan Yanik, Deniz Emre, Meltem Alp, Fatih Algi, Selehattin Yilmaz, Ali Bilici, Dilsat Ozkan-Ariksoysal
Summary: The study demonstrates the performance of a newly developed nanomaterial-based biosensor for the analysis of drug-DNA interaction. The nanomaterial-modified sensor showed significantly higher sensitivity compared to the bare electrode. The developed nanobiosensor system provided highly specific determination between the anticancer drug Mitomycin C and the drug Acyclovir by discriminating their interactions with double-stranded DNA.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2023)
Article
Chemistry, Inorganic & Nuclear
Karmel S. Gkika, Sara Noorani, Naomi Walsh, Tia E. Keyes
Summary: This study shows that cell permeability can be promoted by non-contiguous sequences of arginine residues bridged across the metal center. The bis-tetraarginine conjugate exhibited excellent cellular uptake and accumulation in two 2D monolayer cell lines, as well as remarkable in-depth penetration of 3D MCTSs in pancreatic cancer cells.
INORGANIC CHEMISTRY
(2021)
Article
Chemistry, Physical
Keshav Kumar Jha, Amrutha Prabhakaran, Christopher S. Burke, Marcus Schulze, Ulrich S. Schubert, Tia E. Keyes, Michael Jaeger, Benjamin Dietzek Ivansic
Summary: Triplet-triplet annihilation upconversion is an emerging technology that has the potential to convert long-wavelength photons to higher photon energies. Transferring the upconversion system from solution to solid matrices is a challenge, but various approaches have been established. This study investigates the effect of integrating molecular sensitizers into a PMMA polymer on the upconversion process, and compares the results to those using a monomeric annihilator.
JOURNAL OF PHYSICAL CHEMISTRY C
(2022)
Article
Chemistry, Physical
Sean Hennessey, Christopher S. Burke, Roberto Gonzalez-Gomez, Debobroto Sensharma, Wenming Tong, Amal, Cherian Kathalikkattil, Fabio Cucinotta, Wolfgang Schmitt, Tia E. Keyes, Pau Farras
Summary: A new multimetallic photoactive coordination polymer with high photostability and unique optical properties has been successfully synthesized.
Article
Chemistry, Inorganic & Nuclear
Komala Pandurangan, Anthony B. Carter, Paulo N. Martinho, Brendan Gildea, Tibebe Lemma, Shang Shi, Aizuddin Sultan, Tia E. Keyes, Helge Mueller-Bunz, Grace G. Morgan
Summary: This study reports the structural and magnetic properties of a new spin crossover complex in lattices with different counterions. Comparison experiments show that alkylation effectively inhibits the thermal spin crossover pathway. Further investigations confirm the stability of the high spin state in dilute environments.
Article
Chemistry, Multidisciplinary
Nirod Kumar Sarangi, Amrutha Prabhakaran, Tia E. Keyes
Summary: Quinacrine is a versatile drug with antimalarial, antianthelmintic, antiprotozoan, and multidrug resistance combating properties. By using microcavity-suspended lipid bilayers as in vitro models, the influence of cholesterol and mixed-lipid composition on the membrane interactions of quinacrine was investigated. Label-free surface-sensitive techniques, such as electrochemical impedance spectroscopy and surface-enhanced Raman spectroscopy, were utilized to study drug permeability and binding behavior.
Review
Chemistry, Multidisciplinary
Karmel S. Gkika, David Cullinane, Tia E. Keyes
Summary: Metal complex luminophores have been widely applied as imaging probes in cell imaging due to the use of peptide-facilitated delivery. The conjugation of cell-permeating or signal peptides to metal complex luminophores allows efficient transportation across the cell membrane. This article discusses the rationale behind using metal complexes as probes and sensors in cell imaging and highlights the advantages of using peptides as carriers for complex luminophores. The article also presents progress in applying peptides in metal complex peptide-driven conjugates for cell permeation and targeting.
TOPICS IN CURRENT CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Daniel Obitz, Karmel S. Gkika, Marvin Heller, Tia E. Keyes, Nils Metzler-Nolte
Summary: A lanthanide(iii) complex connected to a light harvesting antenna was synthesized and tested as a potential photosensitizer in photodynamic therapy. The complex showed significant phototoxic activity on cancer cells upon irradiation, with ROS production identified as the compound's phototoxic mode of action. In cell viability assays, a 10-fold decrease in IC50 value was observed compared to the dark control.
CHEMICAL COMMUNICATIONS
(2023)
Article
Chemistry, Inorganic & Nuclear
Lorcan Holden, Karmel S. Gkika, Christopher S. Burke, Conor Long, Tia E. Keyes
Summary: This study reports a Ru(II) complex (Ru-PDC3) that combines the light switch capability of a Ru(II) dipyridylphenazine complex with the well-known G4-selective ligand Phen-DC3 into a single structure. The complex exhibits the expected light switch effect and strong affinity for G4 structures, while also possessing a powerful G4 disrupting capability. Additionally, the complex is fully water-soluble and readily permeable to live cells.
INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Physical
Jack Robinson, Nirod Kumar Sarangi, Tia E. Keyes
Summary: The study shows that Aβ(1-42) induces oligomerization on the outer leaflet of membranes containing DOPS, leading to membrane damage and solute leakage, with the effects dependent on the concentrations of DOPS and Aβ(1-42) as well as time.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2023)
Article
Chemistry, Multidisciplinary
Ruben Arturo Arellano-Reyes, Amrutha Prabhakaran, Rengel Cane E. Sia, Julien Guthmuller, Keshav Kumar Jha, Tingxiang Yang, Benjamin Dietzek-Ivansic, Vickie McKee, Tia E. Keyes
Summary: BODIPY heterochromophores with perylene and/or iodine substituents at the 2 and 6 positions were investigated for their potential as sensitizers in triplet-triplet annihilation up conversion (TTA-UC). The compounds exhibited strong charge transfer absorption and emission properties, and were effective sensitizers for TTA-UC with perylene annihilator in dioxane and DMSO solvents. The emission profiles remained characteristic of charge transfer transition across all solvents tested.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Rafaela T. Marques, Liliana P. Ferreira, Clara S. B. Gomes, Catia S. D. Lopes, Carlos E. S. Bernardes, Nirod Kumar Sarangi, Tia E. Keyes, Paulo N. Martinho
Summary: The storage of guest molecules in nonporous single crystals is an important development in the field of smart materials. We describe the synthesis and characterization of the new spin crossover Fe(III) compound [Fe(3-Br,5-ClsalEen)2]BPh4 center dot CH3CN center dot H2O (salEen = N-ethyl-N-(2-aminoethyl)salicylaldiminate) and its reversible single-crystal-to-single-crystal transformation upon desolvation and resolvation of the crystals. This compound behaves as a spin crossover sponge, and the desolvation/resolvation dynamics were studied through kinetic analysis.
CRYSTAL GROWTH & DESIGN
(2023)
Article
Chemistry, Physical
Arpita Roy, Nirod Kumar Sarangi, Surajit Ghosh, Amrutha Prabhakaran, Tia E. Keyes
Summary: Antimicrobial peptides (AMPs) have significant potential in combating antibiotic resistance by targeting microbial membrane without harming mammalian cells. This study investigated the interactions and synergistic effects of two AMPs, magainin 2 and PGLa, on bacterial and mammalian membrane models. The combined AMPs formed toroidal pores, while individual AMPs only affected the exterior leaflet of the bacterial model. The impact on a ternary, mammalian mimetic membrane was much weaker.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2023)
Article
Chemistry, Inorganic & Nuclear
Rhianne C. C. Curley, Christopher S. S. Burke, Karmel S. S. Gkika, Sara Noorani, Naomi Walsh, Tia E. E. Keyes
Summary: Parent and peptide conjugates of bistridentate Ru(II) complexes with expanded bite angles demonstrate high phototoxicity and exceptional permeability in both 2D and 3D cell models for potential use in photodynamic therapy. The Ru(II) complexes show enhanced emission quantum yields and lifetimes, promoting their photoinduced singlet oxygen production. The complexes exhibit significant phototoxicity toward pancreatic cancer cell monolayers, with phototoxic indices ranging from 580 to 760.
INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Inorganic & Nuclear
Meenaxi Saini, Tia E. Keyes
Summary: Pt1 selectively emits luminescence when binding to G-quadruplex rather than duplex DNA, with enhanced effect on parallel and hybrid G-quadruplex structures. The kinetics of binding are studied for c-myc and the response is partially reversible in a displacement assay.
DALTON TRANSACTIONS
(2023)
Article
Chemistry, Multidisciplinary
Chao-Yi Yao, Hong-Yu Lin, Philip Morgenfurt, Tia E. Keyes, A. Prasanna de Silva
Summary: This article introduces shape-switchable cyclophane hosts that can capture and release reactive polypyridineRu(ii) complexes in water. This leads to a network of host-guest binding, acid-base reactions, and chemical redox interconversions. The study of (2-(2'-pyridyl)imidazole)Ru(ii) complexes reveals the emergence of molecular logic gate arrays of varying complexity. The luminescence switching in neutral solution is attributed to the features of the aromatic hosts, including enhanced radiative decay and suppressed nonradiative decay involving deprotonation by reducing the water content within the deep host cavity. These findings demonstrate the control of nanometric coordination chemistry/physics through inclusion in an open box. The shape-switching mechanism of wall collapse/erection is also influenced by the aromatic units of the macrocycle.