Article
Chemistry, Multidisciplinary
Luis Zamora-Peredo, Josue Ismael Garcia-Ramirez, Amado Carlos Garcia-Velasco, Julian Hernandez-Torres, Leandro Garcia-Gonzalez, Monserrat Bizarro, Adriana Baez-Rodriguez
Summary: This study fabricated ZnO microspheres and Ag/ZnO microspheres using hydrothermal and photodeposition methods, and found that the SERS substrate grown at 9.8 mM during 30 min showed the best SERS activity, with the ability to detect methylene blue at 10(-9) M concentration.
Article
Chemistry, Multidisciplinary
Thi Thuy Nguyen, Fayna Mammeri, Souad Ammar, Thi Bich Ngoc Nguyen, Trong Nghia Nguyen, Thi Ha Lien Nghiem, Nguyen Thi Thuy, Thi Anh Ho
Summary: This study reports the formation of silver nanopetal-Fe3O4 poly-nanocrystals assemblies and their application as active substrates for Surface Enhanced Raman Spectroscopy (SERS). The engineered Fe3O4-Ag architectures exhibit plasmonic properties that offer a rough surface with plenty of hot spots for enhancing electrical fields, making them valuable for ultra-sensitive SERS sensing with magnetically assisted collection. Successful detection of trace amounts of Rhodamine 6G (R6G) down to 10(-10) M in water at room temperature was achieved.
Article
Chemistry, Multidisciplinary
Rajeev K. Sinha
Summary: This study reported the fabrication of a surface-enhanced Raman spectroscopy (SERS) substrate on a simple hydrophobic surface and compared two different preparation methods. It was found that a specific preparation method resulted in smaller dried spot size and higher sensitivity to detect target molecules in SERS experiments.
Article
Chemistry, Analytical
Cheng-Ju Sung, Szu-Han Chao, Shih-Chieh Hsu
Summary: This report summarizes the development of biosensors for Rhodamine 6G and in vitro glucose detection based on surface-enhanced Raman scattering technology. The use of NPS-AuFON as the sensor platform, combined with potentiostatic technique and electrochemical adsorption, allowed for optimal detection of low concentrations of glucose. The surface modification technology achieved the goal of detecting a glucose concentration of 11.1 mmol/L (mg/dL) to determine diabetic status, as set by the World Health Organization.
Article
Spectroscopy
Shaoyun Chen, Qi Li, Du Tian, Pai Ke, Xinxin Yang, Qingyun Wu, Jian Chen, Chenglong Hu, Hongbing Ji
Summary: The evaporation-induced aggregation was used to assemble long silver nanowires into a highly aligned structure to achieve uniform hot spots for SERS detection. The glass slide with well-aligned silver nanowires acted as a high sensitivity and excellent reproducibility SERS substrate for detecting analytes.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Physical
Nazar Riswana Barveen, Tzyy-Jiann Wang, Yu-Hsu Chang, Zhe Yuan-Liu
Summary: The study constructed semiconductor/noble-metal heterostructure flower-like ZnO@Ag nanostructures with high SERS activity for detecting multiple food colorants with high sensitivity and excellent uniformity.
JOURNAL OF ALLOYS AND COMPOUNDS
(2021)
Article
Chemistry, Physical
Ilya Korolkov, A. Shumskaya, Artem L. Kozlovskiy, Malik E. Kaliyekperov, Lana Lissovskaya, Maxim Zdorovets
Summary: The paper describes the synthesis of a substrate for surface enhanced Raman spectroscopy (SERS) using magnetic nickel nanotubes (Ni NTs) and its application in quantitative analysis of organic molecules. The success of the substrate is achieved by depositing a gold layer on the Ni NTs and the purity and uniformity of the gold layer are confirmed through various analysis methods. The study shows that the magnetic properties of the obtained magnetic Ni-Au NTs remain unchanged compared to the initial Ni nanotubes, and the substrates exhibit high SERS enhancement efficiency.
JOURNAL OF ALLOYS AND COMPOUNDS
(2022)
Article
Chemistry, Physical
P. Varasteanu, A. M. Bujor, C. Pachiu, G. Craciun, I. Mihalache, V. Tucureanu, C. Romanitan, R. Pascu, A. Boldeiu
Summary: Silver-based nanostructures, especially anisotropic ones such as triangular nanoplates, nanorods, nanocubes or silver nanowires, are used as Surface enhanced Raman scattering substrates for different analytes sensing, with outstanding results, in terms of the limit of detection (LOD) and the enhancement factor (EF). These nanostructures have shown great applicability in early clinical cancer diagnosis, trace level detection of organic pollutants, pesticide detection, and even explosives.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Environmental Sciences
Kandi Sridhar, Baskaran Stephen Inbaraj, Bing-Huei Chen
Summary: This study developed a paper-based SERS method using grape skin-gold nanoparticles/graphene oxide as a substrate, which showed high sensitivity and stability for detecting organic toxins. It can be applied to real water and food samples with good recovery rates.
Article
Materials Science, Multidisciplinary
Yongxing Lin, Pengfei Qi, Jincheng Liu, Yizhi Zhuo, Cheng Cai, Haibao Zhang, Xiangyang Li, Xianglan Liu, Lin Chen, Sihai Luo, Xingyou Tian
Summary: Large-area gold-coated polyamide 66 nanopillar arrays (PA66NP@Au) with secondary lamellar structures and sub-10-nm gaps were fabricated for surface-enhanced Raman spectroscopy (SERS) using anodized aluminum oxide template, solution-phase growth of PA66 lamellae, and Au sputtering. These closely packed PA66NP@Au arrays exhibited high SERS sensitivity for detection of rhodamine 6g (R6G) molecules with concentration down to 10(-14) m and a large Raman analytical enhancement factor (AEF) of & AP;10(10). Moreover, the PA66NP@Au arrays showed highly sensitive detection of carbendazim, a commonly found pesticide residue, with a limit of detection (LOD) of 0.05 mg L-1 (0.05 ppm), which is lower than the maximum residue limit allowed in Europe Union.
ADVANCED MATERIALS TECHNOLOGIES
(2023)
Article
Chemistry, Physical
O. E. Cigarroa-Mayorga, S. Gallardo-Hernandez, P. Talamas-Rohana
Summary: In this study, SERS substrates were synthesized by growing Au nanoparticles layer over porous anodized aluminum oxide support, with the strongest effect observed in a 50 nm Au precursor layer. The method is highly reproducible and has a homogeneous size distribution compared to other methods and substrates.
APPLIED SURFACE SCIENCE
(2021)
Article
Nanoscience & Nanotechnology
Xin Wang, Seokgyun Ham, Wei Zhou, Rui Qiao
Summary: In this study, molecular dynamics simulations were used to investigate the adsorption of rhodamine 6G and choline molecules on gold electrodes with different surface charges. The results show that both molecules can adsorb on gold surfaces at all surface charge densities, but the adsorption mechanisms and configurations may vary.
Article
Nanoscience & Nanotechnology
Jyh-hwa Kau, Xin-an Chen, Chia-ying Chin, Cheng-cheung Chen, Shun-lin Chiu, Hui-ju Yen, Jenn-jong Young
Summary: In this study, silver nanocubes were successfully synthesized via the silver mirror reaction within 1 minute. The sharp-edge nanocubes quickly transformed into small spherical nanoparticles and aggregates to extend the reaction time. A membrane-based surface-enhanced Raman scattering (SERS) substrate with high sensitivity and reproducibility was developed, and the fabrication process was completed within 30 minutes. The substrate demonstrated attomolar sensitivity to R6G and could detect various analytes with low limits of detection. However, the substrate's sensitivity decreased after 3 days.
ACS APPLIED NANO MATERIALS
(2023)
Article
Spectroscopy
Dipanwita Majumdar, Subhajit Jana, Samit Kumar Ray
Summary: In this study, a nanohybrid SERS platform was developed by decorating two-dimensional WSe2 flakes with zero-dimensional Au NPs. The hybrid structure exhibited promising SERS activity with a detection limit as low as 10(-9) M, along with reliable signal stability and reproducibility. These results indicate the great potential of the nanohybrid structure in SERS applications.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Multidisciplinary
Chulsoo Kim, Byungyou Hong, Wonseok Choi
Summary: Surface-enhanced Raman scattering (SERS) is a highly sensitive technique for detecting DNA, proteins, and single molecules. The study utilized carbon nanowall and embedded plasmonic nanoparticles to increase hotspot density, resulting in robust Raman signals.
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)