Raf Kinase Inhibitor Protein (RKIP) Dimer Formation Controls Its Target Switch from Raf1 to G Protein-coupled Receptor Kinase (GRK) 2

A New Model for Raf Kinase Inhibitory Protein Induced Chemotherapeutic Resistance

(2012) Fahd Al-Mulla et al.   PLoS One

Raf Kinase Inhibitor Protein RKIP Enhances Signaling by Glycogen Synthase Kinase-3β

(2011) Fahd Al-Mulla et al.   CANCER RESEARCH

G Protein Coupled Receptor Kinases as Therapeutic Targets in Cardiovascular Disease

(2011) Stephen L. Belmonte et al.   CIRCULATION RESEARCH

Molecular Mechanism of Selectivity among G Protein-Coupled Receptor Kinase 2 Inhibitors

(2011) D. M. Thal et al.   MOLECULAR PHARMACOLOGY

Raf kinases in cancer–roles and therapeutic opportunities

(2011) G Maurer et al.   ONCOGENE

G protein-coupled receptor kinases: More than just kinases and not only for GPCRs

(2011) Eugenia V. Gurevich et al.   PHARMACOLOGY & THERAPEUTICS

Phosphorylation in Protein-Protein Binding: Effect on Stability and Function

(2011) Hafumi Nishi et al.   STRUCTURE

Analysis of Monomeric and Dimeric Phosphorylated Forms of Protein Kinase R

(2010) Eric Anderson et al.   BIOCHEMISTRY

GRK2 as a novel gene therapy target in heart failure

(2010) Giuseppe Rengo et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Characterization of the Raf Kinase Inhibitory Protein (RKIP) Binding Pocket: NMR-Based Screening Identifies Small-Molecule Ligands

(2010) Anne N. Shemon et al.   PLoS One

Mechanisms of protein oligomerization, the critical role of insertions and deletions in maintaining different oligomeric states

(2010) K. Hashimoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Raf Kinase Inhibitor Protein Enhances Neuronal Differentiation in Human SH-SY5Y Cells

(2009) Julian Hellmann et al.   DEVELOPMENTAL NEUROSCIENCE

Cardiac hypertrophy: Targeting Raf/MEK/ERK1/2-signaling

(2009) Kristina Lorenz et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Evolution of Protein Binding Modes in Homooligomers

(2009) Judith E. Dayhoff et al.   JOURNAL OF MOLECULAR BIOLOGY

Raf kinase inhibitory protein: a signal transduction modulator and metastasis suppressor

(2008) Alexey E Granovsky et al.   CELL RESEARCH

The RKIP (Raf-1 Kinase Inhibitor Protein) conserved pocket binds to the phosphorylated N-region of Raf-1 and inhibits the Raf-1-mediated activated phosphorylation of MEK

(2008) Oliver Rath et al.   CELLULAR SIGNALLING

G Protein–Coupled Receptor Kinase 2 Ablation in Cardiac Myocytes Before or After Myocardial Infarction Prevents Heart Failure

(2008) Philip W. Raake et al.   CIRCULATION RESEARCH

Raf kinase inhibitory protein (RKIP): A physiological regulator and future therapeutic target

(2008) Lingchun Zeng et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Raf Kinase Inhibitory Protein Function Is Regulated via a Flexible Pocket and Novel Phosphorylation-Dependent Mechanism

(2008) A. E. Granovsky et al.   MOLECULAR AND CELLULAR BIOLOGY

A new type of ERK1/2 autophosphorylation causes cardiac hypertrophy

(2008) Kristina Lorenz et al.   NATURE MEDICINE

Built-in loops allow versatility in domain-domain interactions: Lessons from self-interacting domains

(2008) E. Akiva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA